Protein Alignment CG5611 and CDYL

DIOPT Version :10

• Sequence 1: NP_651574.1
• Gene: CG5611 / 43318
• FlyBaseID: FBgn0039531
• Length: 326
• Species: Drosophila melanogaster
• Sequence 2: NP_001355054.1
• Gene: CDYL / 9425
• HGNCID: 1811
• Length: 598
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 53/214 - (24%)
• Similarity: 93/214 - (43%)
• Gaps: 31/214 - (14%)

  Fly    26 TVRNAESESQEGAPARTVLVEKDSHITLIGLN-REQQRNSIDANTAEQLTEAISQFEADDTSPVG 89
            :||..||..:    .|.::|.|....|.|.|: :..:.||::.....::..|:|...|||:..|
Human   331 SVRQTESAYR----YRDIVVRKQDGFTHILLSTKSSENNSLNPEVMREVQSALSTAAADDSKLV- 390

  Fly    90 VLYGIGGSFCAGYDL-------------EELE-AEAQRGSLNFLLRHEGSVGPTRRHLRKPLVCG 140
            :|..:|..||.|.|.             |..: |||.|..:|..::           .:||::..
Human   391 LLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVNTFIQ-----------FKKPIIVA 444

  Fly   141 ISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIATGRRI 205
            ::|..:..|..:..:||:....:.|.........|.......||.....:|.::|.|::.:||::
Human   445 VNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKL 509

  Fly   206 YSGEARRIGLVNRVVATGT 224
            .:.||...|||::|...||
Human   510 TAQEACGKGLVSQVFWPGT 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5611	NP_651574.1	crotonase-like	39..256	CDD:474030	49/201 (24%)
CDYL	NP_001355054.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..76
		Interaction with EZH2. /evidence=ECO:0000269|PubMed:22009739	61..309
		CD_CDY	62..111	CDD:349284
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	112..149
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..226
		crotonase-like	344..540	CDD:119339	48/197 (24%)
		Acetyl-CoA-binding domain. /evidence=ECO:0000255	362..594		43/179 (24%)