Protein Alignment CG5611 and HIBCH

DIOPT Version :10

• Sequence 1: NP_651574.1
• Gene: CG5611 / 43318
• FlyBaseID: FBgn0039531
• Length: 326
• Species: Drosophila melanogaster
• Sequence 2: NP_055177.2
• Gene: HIBCH / 26275
• HGNCID: 4908
• Length: 386
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 81/322 - (25%)
• Similarity: 137/322 - (42%)
• Gaps: 61/322 - (18%)

  Fly     1 MSRFVYKLLQSANQTSSGCRRISLATVRNAESESQEGAPARTVLVEKDSHITLIGLNREQQRNSI 65
            ||||     .:..:|::....:.::...:|..|         ||:||.....:|.|||.:..|::
Human    10 MSRF-----NAFKRTNTILHHLRMSKHTDAAEE---------VLLEKKGCTGVITLNRPKFLNAL 60

  Fly    66 DANTAEQLTEAISQFEADDTSPVGVLYGIGG-SFCAGYDLEEL-EAE-AQRGSLNFLLRHEGSVG 127
            ..|...|:...:.::|.|..:.:.::.|.|| :||||.|:..: ||| |::.......|.|..:.
Human    61 TLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLN 125

  Fly   128 PTRRHLRKPLVCGISGFCVAGGLELALMCDLRV--------MEDTAVLGFFNRRLGVPLSDGG-- 182
            ......:||.|..|.|..:.||:.|::....||        |.:||: |.|      |...||
Human   126 NAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAI-GLF------PDVGGGYF 183

  Fly   183 TVRLAAAVGYSNALEIIATGRRIYSGEARRIGLVNRVV-ATGTALGQAVNLAF-SIAKFPMASLM 245
            ..||...:||..||    ||.|:...:..|.|:....| :...|:.:...||. |.:|..:||::
Human   184 LPRLQGKLGYFLAL----TGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVL 244

  Fly   246 ----------HDRNAVLENANAYNKPGFHVASYNEIM--NVTSDMITDMQEGVKRFKNSEIK 295
                      .|::.:||.         |:...|...  |...::|.::|:....|...::|
Human   245 ENYHTESKIDRDKSFILEE---------HMDKINSCFSANTVEEIIENLQQDGSSFALEQLK 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5611	NP_651574.1	crotonase-like	39..256	CDD:474030	67/241 (28%)
HIBCH	NP_055177.2	ECH_2	46..376	CDD:465024	70/272 (26%)