DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5611 and CDYL2

DIOPT Version :10

Sequence 1:NP_651574.1 Gene:CG5611 / 43318 FlyBaseID:FBgn0039531 Length:326 Species:Drosophila melanogaster
Sequence 2:XP_011521168.1 Gene:CDYL2 / 124359 HGNCID:23030 Length:540 Species:Homo sapiens


Alignment Length:286 Identity:64/286 - (22%)
Similarity:108/286 - (37%) Gaps:75/286 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 FVYKLLQSANQTSSGCRRISLATVRNAESESQEGAPARTVLVEKDSHITLIGLNRE-QQRNSIDA 67
            |..:|..|..|..|.||                   .|.::|.|:...|.|.|:.: ...|::..
Human   266 FDKRLRYSVRQNESNCR-------------------FRDIVVRKEEGFTHILLSSQTSDNNALTP 311

  Fly    68 NTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEEL--------------EAEAQRGSLNF 118
            ...:::..|:.....|| |.:.:|..:|..||:|.|...|              .|||.|..:..
Human   312 EIMKEVRRALCNAATDD-SKLLLLSAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVKA 375

  Fly   119 LLRHEGSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGT 183
            .::           .:||:|..|:|..:..|..:..:||:....:.|   :|.    .|.:   |
Human   376 FIQ-----------FKKPIVVAINGPALGLGASILPLCDIVWASEKA---WFQ----TPYA---T 419

  Fly   184 VRLAAA----------VGYSNALEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAK 238
            :||..|          :|.:.|.|::..||::.:.||...|||::|. ..|...|.|.|......
Human   420 IRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSRGLVSQVF-WPTTFSQEVMLRVKEMA 483

  Fly   239 FPMASLMHDR--------NAVLENAN 256
            ...|.::.:.        .:|||:.|
Human   484 SCSAVVLEESKCLVRSFLKSVLEDVN 509

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5611NP_651574.1 crotonase-like 39..256 CDD:474030 56/249 (22%)
CDYL2XP_011521168.1 CD_CDY 42..91 CDD:349284
crotonase-like 286..482 CDD:119339 51/218 (23%)
Blue background indicates that the domain is not in the aligned region.

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