DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tusp and TLP1

DIOPT Version :9

Sequence 1:	NP_001263014.1	Gene:	Tusp / 43317	FlyBaseID:	FBgn0039530	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_001319391.1	Gene:	TLP1 / 844025	AraportID:	AT1G76900	Length:	455	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	112/521 - (21%)
Similarity:	173/521 - (33%)	Gaps:	186/521 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly  1017 SLDSCDLLSLQTKLSS--KE------------HEQVVRKLQEISDSSACSSAANTLCFKCRNNMS 1067
            |:.|....|...||||  ||            .||:|..:||...:                |:.
plant    13 SIGSLSRRSFDFKLSSLNKEGGKSRGSVQDSHEEQLVVTIQETPWA----------------NLP 61

  Fly  1068 PS---SACKRCQPSASSVLDEITAVVPAVEPAKESPAVQAKPAPKKRFDVITSFTDSPLFTRKHR 1129
            |.   ...||.:.|.|            |.||:......|......| |:......||..:.|..
plant    62 PELLRDVIKRLEESES------------VWPARRHVVACASVCRSWR-DMCKEIVQSPELSGKIT 113

  Fly  1130 FGIGRSKETAGTENSTPLLGRKQDNG---FSFVKQLSEVRWRRKEQPAQAQVNGS--SNASTLER 1189
            |.:  |.:..|..::|.....|:|..   :.....||         ||....||.  .:|..:.|
plant   114 FPV--SLKQPGPRDATMQCFIKRDKSNLTYHLYLCLS---------PALLVENGKFLLSAKRIRR 167

  Fly  1190 QPQPEITGAACGTVEATPVEAKASVSLHTQALTTLEN-IISRLRDLDEGRL-----TPPSTPQRL 1248
            ....|..                 :|:|...::...| .|.::|....|..     |.|:....:
plant   168 TTYTEYV-----------------ISMHADTISRSSNTYIGKIRSNFLGTKFIIYDTQPAYNSNI 215

  Fly  1249 PRS---------------SPASPAASKKNKRQQSNSPIRHILNSPLLNRRQRKK-----QSIIES 1293
            .|:               ||..|:.|.|      .:.:.:.||  :|..|..::     .||..|
plant   216 ARAVQPVGLSRRFYSKRVSPKVPSGSYK------IAQVSYELN--VLGTRGPRRMHCAMNSIPAS 272

  Fly  1294 SDDEGNQTNGSGE-------------------------ESNNAGNGKQYRD----LETFQKAQLR 1329
            |..||....|..:                         :.:|..:..::.|    |...|:..|.
plant   273 SLAEGGTVPGQPDIIVPRSILDESFRSITSSSSRKITYDYSNDFSSARFSDILGPLSEDQEVVLE 337

  Fly  1330 QKLKRGKIEPNGSASCANPAPVRREFVMHNKAPMWNEMSQVYQLDFGGRVTQESAKNFQI----- 1389
            :..:|            |..|:    |:.||.|.|:|..|.:.|:|.||||..|.||||:
plant   338 EGKER------------NSPPL----VLKNKPPRWHEQLQCWCLNFRGRVTVASVKNFQLIAANQ 386

  Fly  1390 -----------------------EFRGKQVMQFGRIDGNAYTLDFQYPFSALQAFAVALANVTQR 1431
                                   :...|.::|||::..:.:|:||:||.||.||||:.|::...:
plant   387 PQPQPQPQPQPQPLTQPQPSGQTDGPDKIILQFGKVGKDMFTMDFRYPLSAFQAFAICLSSFDTK 451

  Fly  1432 L 1432
            |
plant   452 L 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tusp	NP_001263014.1	WD40	51..>295	CDD:225201
		WD40	81..359	CDD:295369
		WD40 repeat	91..126	CDD:293791
		WD40 repeat	132..168	CDD:293791
		WD40 repeat	173..208	CDD:293791
		WD40 repeat	216..263	CDD:293791
		WD40 repeat	270..333	CDD:293791
		Tub	<588..>644	CDD:279506
		Tub	<1355..1426	CDD:279506	33/98 (34%)
TLP1	NP_001319391.1	F-box-like	57..>99	CDD:372399	12/70 (17%)
TLP1	NP_001319391.1	Tub	120..450	CDD:366500	80/379 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1445357at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16517
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.980