DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tusp and TLP7

DIOPT Version :9

Sequence 1:	NP_001263014.1	Gene:	Tusp / 43317	FlyBaseID:	FBgn0039530	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_564627.1	Gene:	TLP7 / 841766	AraportID:	AT1G53320	Length:	379	Species:	Arabidopsis thaliana

Alignment Length:	389	Identity:	96/389 - (24%)
Similarity:	152/389 - (39%)	Gaps:	116/389 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1144 STPLLGRKQDNGFSFVKQLSEVRWRRKEQPAQAQVNGSSNASTLERQPQPEITGAACGTVEAT-- 1206
            |..||.|:..|.|.|.:..:......:..|..:.:.|||:.|.:    .||:.|.....||.|
plant     4 SRSLLSRRISNSFRFHQGETTTAPESESIPPPSNMAGSSSWSAM----LPELLGEIIRRVEETED 64

  Fly  1207 ------PVEAKASVSLHTQALTTLENIISRLRDLDEGRLTPPSTPQRLPRSSP---ASPAASKKN 1262
                  .|...|.||...:.:|   :..:| ..|:.|::|.||. .:||  .|   ::....|:|
plant    65 RWPQRRDVVTCACVSKKWREIT---HDFAR-SSLNSGKITFPSC-LKLP--GPRDFSNQCLIKRN 122

  Fly  1263 KRQQSNSPIRHILNSP---------LLNRRQRK---KQSIIESSDDEGNQ--------------- 1300
            |:  :::...::..:|         |..||.|.   .:.||....|:.:|
plant   123 KK--TSTFYLYLALTPSFTDKGKFLLAARRFRTGAYTEYIISLDADDFSQGSNAYVGKLRSDFLG 185

  Fly  1301 TNGSGEES----NNA--GNGKQYRDLETFQKAQLRQKLKRGKIE---------------PNGSAS 1344
            ||.:..:|    |.|  .|||..|   .|...|:..::..|..|               |....|
plant   186 TNFTVYDSQPPHNGAKPSNGKASR---RFASKQISPQVPAGNFEVGHVSYKFNLLKSRGPRRMVS 247

  Fly  1345 ---CANPAPVRRE--------------------------FVMHNKAPMWNEMSQVYQLDFGGRVT 1380
               |.:|:|....                          .::.||||.|:|..|.:.|:|.||||
plant   248 TLRCPSPSPSSSSAGLSSDQKPCDVTKIMKKPNKDGSSLTILKNKAPRWHEHLQCWCLNFHGRVT 312

  Fly  1381 QESAKNFQI-------EFRGK-----QVMQFGRIDGNAYTLDFQYPFSALQAFAVALANVTQRL 1432
            ..|.||||:       :..||     .::|||::..:.:|:|::.|.||.||||:.|.:...:|
plant   313 VASVKNFQLVATVDQSQPSGKGDEETVLLQFGKVGDDTFTMDYRQPLSAFQAFAICLTSFGTKL 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tusp	NP_001263014.1	WD40	51..>295	CDD:225201
		WD40	81..359	CDD:295369
		WD40 repeat	91..126	CDD:293791
		WD40 repeat	132..168	CDD:293791
		WD40 repeat	173..208	CDD:293791
		WD40 repeat	216..263	CDD:293791
		WD40 repeat	270..333	CDD:293791
		Tub	<588..>644	CDD:279506
		Tub	<1355..1426	CDD:279506	32/82 (39%)
TLP7	NP_564627.1	F-box	42..89	CDD:395521	13/53 (25%)
TLP7	NP_564627.1	Tub	108..374	CDD:395929	65/272 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1445357at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16517
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.980