DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tusp and TLP11

DIOPT Version :9

Sequence 1:	NP_001263014.1	Gene:	Tusp / 43317	FlyBaseID:	FBgn0039530	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_197369.2	Gene:	TLP11 / 831986	AraportID:	AT5G18680	Length:	389	Species:	Arabidopsis thaliana

Alignment Length:	437	Identity:	95/437 - (21%)
Similarity:	165/437 - (37%)	Gaps:	112/437 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  1028 TKLSSKEH------EQVVRKL---QEISDSSACSSAANTLCFKCRNNMSPSSACKRCQPSASSVL 1083
            |.:||:::      |:::|::   .|.:|.....|.        |:.::.:..|:..:     :|
plant    30 TSVSSQDYRWSEIPEELLREILIRVEAADGGGWPSR--------RSVVACAGVCRGWR-----LL 81

  Fly  1084 DEITAVVPAVEPAKESPAVQAKPAPKKRFDVITSFTDSPLFTRKHRFGIGRSKETAGTENSTPLL 1148
            ...|.|||.:......|....:|.|  |..::..|......|:.:...:|.:...  |::...||
plant    82 MNETVVVPEISSKLTFPISLKQPGP--RDSLVQCFIKRNRITQSYHLYLGLTNSL--TDDGKFLL 142

  Fly  1149 GR---KQDNGFSFVKQLSEVRWRRKEQPAQAQVNGSSNASTLERQPQPEITGAACGTVEATPVEA 1210
            ..   |......::..|......|:.|                         |..|.|.:..:..
plant   143 AACKLKHTTCTDYIISLRSDDMSRRSQ-------------------------AYVGKVRSNFLGT 182

  Fly  1211 KASVSLHTQALTTLENIISRLRDLDEGRLTPPSTPQRLPRSSPASPAASKKNKRQQSNSPIRHI- 1274
            |.:|.                    :|.|.|.:...:|.:|...:| |....|....:.|:.||
plant   183 KFTVF--------------------DGNLLPSTGAAKLRKSRSYNP-AKVSAKVPLGSYPVAHIT 226

  Fly  1275 --LNSPLLNRRQRKKQSIIESSDDEGNQTNGSGEESNNAGNGKQYRDLETFQKAQLRQKLKRGKI 1337
              || .|.:|..||.|.::::......:..|...|.:.            |.....|..|.|.:.
plant   227 YELN-VLGSRGPRKMQCLMDTIPTSTMEPQGVASEPSE------------FPLLGTRSTLSRSQS 278

  Fly  1338 EP-NGSASCANPAPVRREFVMHNKAPMWNEMSQVYQLDFGGRVTQESAKNFQIEFRG-------- 1393
            :| ..|:|.....|:    |:.||.|.|:|..:.:.|:|.||||..|.||||:...|
plant   279 KPLRSSSSHLKETPL----VLSNKTPRWHEQLRCWCLNFHGRVTVASVKNFQLVAAGASCGSGTG 339

  Fly  1394 --------KQVMQFGRIDGNAYTLDFQYPFSALQAFAVALANVTQRL 1432
                    :.::|||::..:.:|:|:.||.||.||||:.|::...|:
plant   340 MSPERQSERIILQFGKVGKDMFTMDYGYPISAFQAFAICLSSFETRI 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tusp	NP_001263014.1	WD40	51..>295	CDD:225201
		WD40	81..359	CDD:295369
		WD40 repeat	91..126	CDD:293791
		WD40 repeat	132..168	CDD:293791
		WD40 repeat	173..208	CDD:293791
		WD40 repeat	216..263	CDD:293791
		WD40 repeat	270..333	CDD:293791
		Tub	<588..>644	CDD:279506
		Tub	<1355..1426	CDD:279506	31/86 (36%)
TLP11	NP_197369.2	Tub	103..384	CDD:395929	78/347 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1445357at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16517
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.980