DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tusp and TLP9

DIOPT Version :9

Sequence 1:	NP_001263014.1	Gene:	Tusp / 43317	FlyBaseID:	FBgn0039530	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_187289.1	Gene:	TLP9 / 819812	AraportID:	AT3G06380	Length:	380	Species:	Arabidopsis thaliana

Alignment Length:	483	Identity:	107/483 - (22%)
Similarity:	177/483 - (36%)	Gaps:	155/483 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   996 RKRQQQEDARRHKLQQTGKSKSLDSCDLLSLQTKLSSKEHEQVVRKL---QEISDSSACSSAANT 1057
            |...|:..:|.|::.....| :.:|.|..|.     |:..|:::|::   .|..|.....|.
plant     4 RSLLQEMRSRPHRVVHAAAS-TANSSDPFSW-----SELPEELLREILIRVETVDGGDWPSR--- 59

  Fly  1058 LCFKCRNNMSPSSACKRCQPSASSVLDEITAVVPAVEPAKESPAVQAKPAPKKRFDVITSFTDSP 1122
                 ||.::.:..|:..:     :|.:....||........|....:..|  |..::..|....
plant    60 -----RNVVACAGVCRSWR-----ILTKEIVAVPEFSSKLTFPISLKQSGP--RDSLVQCFIKRN 112

  Fly  1123 LFTRKHRFGIGRSKETAGTENSTPLLGRKQDNGFSFVKQLSEVRWRRKEQPAQAQVNGSSNASTL 1187
            ..|:.:...:|.:  |:.|:|...||.                                  ||.|
plant   113 RNTQSYHLYLGLT--TSLTDNGKFLLA----------------------------------ASKL 141

  Fly  1188 ERQPQPEITGAACGTVEATPVEAKASVSLHTQALTTLEN-IISRLRD--------LDEGRLTPPS 1243
            :|        |.|         ....:||.:..::...| .:.|:|.        :.:|..|..:
plant   142 KR--------ATC---------TDYIISLRSDDISKRSNAYLGRMRSNFLGTKFTVFDGSQTGAA 189

  Fly  1244 TPQRLPRS-----SPASPAASKKNKRQQSNSPIRHILNSPLLN-------RRQR-----KKQSII 1291
            ..|:...|     ||..|         |.:.||.||  |..||       ||.|     ...||:
plant   190 KMQKSRSSNFIKVSPRVP---------QGSYPIAHI--SYELNVLGSRGPRRMRCIMDTIPMSIV 243

  Fly  1292 ESSDDEGNQTNGSGEESNNAGNGKQYRDLETFQKAQLRQKLKRGKIEP--NGSASCANPA----- 1349
            ||          .|..::.:.:....|....|          |...:|  :.||||::..
plant   244 ES----------RGVVASTSISSFSSRSSPVF----------RSHSKPLRSNSASCSDSGNNLGD 288

  Fly  1350 -PVRREFVMHNKAPMWNEMSQVYQLDFGGRVTQESAKNFQI---------EFRGKQVMQFGRIDG 1404
             |:    |:.||||.|:|..:.:.|:|.||||..|.||||:         :...:.::|||::..
plant   289 PPL----VLSNKAPRWHEQLRCWCLNFHGRVTVASVKNFQLVAVSDCEAGQTSERIILQFGKVGK 349

  Fly  1405 NAYTLDFQYPFSALQAFAVALANVTQRL 1432
            :.:|:|:.||.||.||||:.|::...|:
plant   350 DMFTMDYGYPISAFQAFAICLSSFETRI 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tusp	NP_001263014.1	WD40	51..>295	CDD:225201
		WD40	81..359	CDD:295369
		WD40 repeat	91..126	CDD:293791
		WD40 repeat	132..168	CDD:293791
		WD40 repeat	173..208	CDD:293791
		WD40 repeat	216..263	CDD:293791
		WD40 repeat	270..333	CDD:293791
		Tub	<588..>644	CDD:279506
		Tub	<1355..1426	CDD:279506	31/79 (39%)
TLP9	NP_187289.1	F-box	31..77	CDD:395521	11/63 (17%)
TLP9	NP_187289.1	Tub	97..375	CDD:395929	85/367 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1445357at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16517
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.980