Protein Alignment Tusp and Tub

DIOPT Version :10

• Sequence 1: NP_001263014.1
• Gene: Tusp / 43317
• FlyBaseID: FBgn0039530
• Length: 1433
• Species: Drosophila melanogaster
• Sequence 2: XP_063138137.1
• Gene: Tub / 25609
• RGDID: 3918
• Length: 548
• Species: Rattus norvegicus
• Alignment Length: 603
• Identity: 143/603 - (23%)
• Similarity: 216/603 - (35%)
• Gaps: 155/603 - (25%)

  Fly   925 QSPTPTPSS-SSMKRTPTVVSIAPAL-PDSITRSCSVGYLDSVAITPSDEALSALRKDAPNKRLI 987
            ||....|:. ::.:|.|:.....|.: |.:.:|:...|       ..|...||..|....:   :
  Rat     3 QSSARAPAGPAARERAPSPAQPPPTVEPQAQSRTEMEG-------VSSHRTLSYSRWSYDS---V 57

  Fly   988 LVDKKRNRRKRQQQEDARRHKLQQTGKSKSLDSCDLLSLQTKLSSKEHEQVVRKLQEISD--SSA 1050
            |.|:..|  .|||:.|.:|..|:|..|.|..:.   |.:|.....:...:..|:.:|.:.  .|.
  Rat    58 LDDEGSN--LRQQKLDRQRALLEQKQKKKRQEP---LMVQANADGRPRSRRARQSEEQAPLVESY 117

  Fly  1051 CSSAANTLCFKCRNNMSPSSACKRCQPSASSVLDEITAVVPAVEPAKESPAVQAK----PAPKKR 1111
            .||:.:|     ...:..:.:....||.|:.        .||...||::....|.    .||:|.
  Rat   118 LSSSGST-----SYQVQEADSLASVQPGATR--------PPAPASAKKTKGAAASGGQGGAPRKE 169

  Fly  1112 FDVITSFTDSPLFTRKHR---------FGIGRSK------ETAGTENSTP----LLGRKQDNGFS 1157
            .......|..|....:.:         ..:|:|.      |||....:.|    |....|..|.|
  Rat   170 KKGKHKGTSGPATLAEDKSEAQGPVQILTVGQSDHAKDAGETAAGGGAQPSGQDLRATMQRKGIS 234

  Fly  1158 FVKQLSEVRWRRKEQPAQAQVNGSSN-ASTLERQPQPEITGAACGTVEATPVEAKASVSLHTQAL 1221
            ......|.....:...:.:|:|.::. :|...|:...|...|........||:.:
  Rat   235 SSMSFDEEEDEDENSSSSSQLNSNTRPSSATSRKSTREAASAPSPAAPEPPVDIE---------- 289

  Fly  1222 TTLENIISRLRDLDEGRLTPPSTPQ------RLPRSSPASPAASKKNKRQQSNSPIRHILNSP-- 1278
                     ::||:|..|.|  .||      |:.|.       .|...|....:...|:....
  Rat   290 ---------VQDLEEFALRP--APQGITIKCRITRD-------KKGMDRGMYPTYFLHLDREDGK 336

  Fly  1279 ---LLNRRQRKKQSI------IESSD-DEGNQTNGSGEESNNAG-------NG--KQYRDLETFQ 1324
               ||..|:|||...      ::.:| ..|..:......||..|       ||  .|.....|.:
  Rat   337 KVFLLAGRKRKKSKTSNYLISVDPTDLSRGGDSYIGKLRSNLMGTKFTVYDNGVNPQKASSSTLE 401

  Fly  1325 KAQLRQKL----------------KRGKIEPN----GSASCANPAPVRRE--------------- 1354
            ...|||:|                |...|.|.    ....|..|   |.|
  Rat   402 SGTLRQELAAVCYETNVLGFKGPRKMSVIVPGMNMVHERVCIRP---RNEHETLLARWQNKNTES 463

  Fly  1355 -FVMHNKAPMWNEMSQVYQLDFGGRVTQESAKNFQIEFRGKQ----VMQFGRIDGNAYTLDFQYP 1414
             ..:.||.|:||:.:|.|.|:|.|||||.|.||||| ..|..    ||||||:..:.:|:|:.||
  Rat   464 IIELQNKTPVWNDDTQSYVLNFHGRVTQASVKNFQI-IHGNDPDYIVMQFGRVAEDVFTMDYNYP 527

  Fly  1415 FSALQAFAVALANVTQRL 1432
            ..||||||:||::...:|
  Rat   528 LCALQAFAIALSSFDSKL 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tusp	NP_001263014.1	WD40	<81..221	CDD:441893
		WD40 repeat	91..126	CDD:293791
		WD40 repeat	132..168	CDD:293791
		WD40 repeat	173..208	CDD:293791
		WD40 repeat	216..263	CDD:293791
		WD40 repeat	270..333	CDD:293791
		Tub	<1249..1426	CDD:460094	68/237 (29%)
Tub	XP_063138137.1	None