DRSC/TRiP Functional Genomics Resources

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Protein Alignment dsd and PAFAH1B3

DIOPT Version :9

Sequence 1:NP_001263013.1 Gene:dsd / 43315 FlyBaseID:FBgn0039528 Length:1323 Species:Drosophila melanogaster
Sequence 2:NP_001139411.1 Gene:PAFAH1B3 / 5050 HGNCID:8576 Length:231 Species:Homo sapiens


Alignment Length:255 Identity:51/255 - (20%)
Similarity:79/255 - (30%) Gaps:82/255 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   322 VGGESYGRGKLMSTYDFNGN-VWETVHPEDGSEVPDKRYGASTVMYGDKIFM------------- 372
            :.||.....|.....|..|: .|.::|....::..||.  ...|..||.:..             
Human     1 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKE--PEVVFIGDSLVQLMHQCEIWRELFS 63

  Fly   373 ------YGGVVKGHGISNELWAFDVSARTWANISVRADPSCNATGGTTAMCGPLHVV-------- 423
                  :|  :.|.|..:.||..:                    .|......|..||        
Human    64 PLHALNFG--IGGDGTQHVLWRLE--------------------NGELEHIRPKIVVVWVGTNNH 106

  Fly   424 GHTATLVPG-------YGDKNNYQYMVVIFGHSPNYGYLNTVQEFNFASREWRIVPTTGYVVKGG 481
            ||||..|.|       ..::...|..||:.|..|...:.|.::|.|....|         :|:..
Human   107 GHTAEQVTGGIKAIVQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNE---------LVRAA 162

  Fly   482 Y-GHSAAYDFLTEKVYVYG-GIVSESESSQVLSSRLYAYEPATRVWSLLSAAPSARLLHT 539
            . ||..|:....:..:|:. |.:|..:        :|.|...:|    |...|..|.||:
Human   163 LAGHPRAHFLDADPGFVHSDGTISHHD--------MYDYLHLSR----LGYTPVCRALHS 210

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dsdNP_001263013.1 CUB 86..212 CDD:238001
PLN02153 290..582 CDD:177814 51/255 (20%)
KELCH repeat 308..349 CDD:276965 7/27 (26%)
Kelch_5 355..391 CDD:290565 10/54 (19%)
KELCH repeat 358..420 CDD:276965 9/80 (11%)
KELCH repeat 424..474 CDD:276965 15/56 (27%)
KELCH repeat 482..531 CDD:276965 10/50 (20%)
KELCH repeat 535..588 CDD:276965 3/5 (60%)
PSI 821..870 CDD:279745
EGF_Lam 948..994 CDD:238012
EGF_Lam 995..1040 CDD:238012
PAFAH1B3NP_001139411.1 PAF_acetylesterase_like 7..205 CDD:238858 46/242 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1388
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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