| Sequence 1: | NP_001263013.1 | Gene: | dsd / 43315 | FlyBaseID: | FBgn0039528 | Length: | 1323 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001258867.1 | Gene: | MEGF8 / 1954 | HGNCID: | 3233 | Length: | 2845 | Species: | Homo sapiens |
| Alignment Length: | 1356 | Identity: | 309/1356 - (22%) |
|---|---|---|---|
| Similarity: | 445/1356 - (32%) | Gaps: | 504/1356 - (37%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 77 GWQGPECQFCGGKVRMYHPMGTIHDGWGNYSVSVKCSWLIDARHPHWNRRHNTNPSRTANIRIHL 141
Fly 142 REFATECGWDHLYIYDGDSVDSPLLAVFSGLMYRGNFSIRRVPQVIATSGTALVHFFSDDAYNMS 206
Fly 207 GFNLTYKMNSCPSDSDEVECSGHGKCR-DGDCICDPMYRGEACNIAACPNNCFESKNQGHCRLDQ 270
Fly 271 ERCSCYEGFAGDDCS----QISAHGAWSTVHPKHSPAPAGSASHGAT----IWRDTLHIVGGESY 327
Fly 328 GR--GKLMSTYDFNGNVWETVHPEDGSEVPDKRYGASTVMYGDKIFMYGGVVKGHGISNELWAFD 390
Fly 391 VSAR-TWANISVRADPSCNATGGTTAMCGPLHVVGHTATLVPGYGDKNNYQYMVVIFGHSPNYGY 454
Fly 455 LNTVQEFNFASRE---WRIVPTTGYVVKGGYGHSAAYDFLTEKVYVYGGIVSESE--SSQVLSSR 514
Fly 515 LYAYEPATRVWSLLSA-----APSARLLHTANFVNQGLMMVFGGNTHNDTSQSYGAKCYSQDLLV 574
Fly 575 YDVYCDSW----HYHPMPGHLQADLA----RFGHSSVVFEES-LYIYGGFNGQLLNDMLRYQ--- 627
Fly 628 -----PG------YCSYYTKQEKCT----------------------AARPGVKCI--------- 650
Fly 651 --------------------WDVQKMRCI--------------------------------AITQ 663
Fly 664 -------------------------------------------VQRSAIY--------------- 670
Fly 671 -----------------------------------------------------GRE--------- 673
Fly 674 QYDYVACPSKSRLTLT---------SEL---LHDVHR---CQELASCQSCVSTAFGCTYC-GNGV 722
Fly 723 CSKER----CRETTSMASVFFESSTQMAVSTASPPLNAKHLDSCPISEEYLVSSVCDQLHNCRAC 783
Fly 784 SANLACRWDSEHNR-----CKSYTSYGGLALNRTQDEVACSPSCASLTNCQNC--TEDECIWCQN 841
Fly 842 EQRCVDRNAYTASFPYGQCREWTTFT---AKCRSAPIQSTALAVGSTTALSSAQCGYYNSCQMCL 903
Fly 904 DDPACGWCDNGSNTGLGRCVVGGALAPYDDTECAL-------------KHWFFTSCP-------- 947
Fly 948 --RC---------------------------NCN-------GHSYCND----------------- 959
Fly 960 ---------------------QQHCEQ-------PCNNLTTGAHCEKCRTGYWGNPINGGKCQRC 996
Fly 997 DCNGQG----VYCHPDTGKCFCT--TKGIVGDHCEKCDSQNHYHGDP-LKGSCYYE 1045 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| dsd | NP_001263013.1 | CUB | 86..212 | CDD:238001 | 48/125 (38%) |
| PLN02153 | 290..582 | CDD:177814 | 78/308 (25%) | ||
| KELCH repeat | 308..349 | CDD:276965 | 13/46 (28%) | ||
| Kelch_5 | 355..391 | CDD:290565 | 9/35 (26%) | ||
| KELCH repeat | 358..420 | CDD:276965 | 13/62 (21%) | ||
| KELCH repeat | 424..474 | CDD:276965 | 12/52 (23%) | ||
| KELCH repeat | 482..531 | CDD:276965 | 13/55 (24%) | ||
| KELCH repeat | 535..588 | CDD:276965 | 17/56 (30%) | ||
| PSI | 821..870 | CDD:279745 | 16/53 (30%) | ||
| EGF_Lam | 948..994 | CDD:238012 | 20/124 (16%) | ||
| EGF_Lam | 995..1040 | CDD:238012 | 19/51 (37%) | ||
| MEGF8 | NP_001258867.1 | CUB | 49..139 | CDD:238001 | 44/109 (40%) |
| Kelch_4 | 227..276 | CDD:290154 | 15/52 (29%) | ||
| KELCH repeat | 228..275 | CDD:276965 | 14/50 (28%) | ||
| Kelch 1 | 241..287 | 15/49 (31%) | |||
| KELCH repeat | 279..331 | CDD:276965 | 12/61 (20%) | ||
| Kelch 2 | 290..338 | 13/57 (23%) | |||
| Kelch 3 | 346..399 | 11/52 (21%) | |||
| Kelch 4 | 402..453 | 13/52 (25%) | |||
| KELCH repeat | 448..510 | CDD:276965 | 20/66 (30%) | ||
| Kelch 5 | 459..511 | 16/55 (29%) | |||
| Kelch 6 | 525..575 | 13/49 (27%) | |||
| PSI | 950..998 | CDD:279745 | 16/47 (34%) | ||
| vWFA | 1011..>1035 | CDD:294047 | 11/23 (48%) | ||
| EGF_3 | 1078..1112 | CDD:289699 | 2/33 (6%) | ||
| EGF_Lam | 1210..1259 | CDD:238012 | 20/53 (38%) | ||
| Kelch 7 | 1522..1570 | ||||
| KELCH repeat | 1566..1612 | CDD:276965 | |||
| Kelch 8 | 1580..1626 | ||||
| KELCH repeat | 1620..1669 | CDD:276965 | |||
| Kelch_3 | 1630..1680 | CDD:290151 | |||
| Kelch 9 | 1632..1679 | ||||
| KELCH repeat | 1672..1720 | CDD:276965 | |||
| Kelch 10 | 1685..1735 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1726..1745 | ||||
| KELCH repeat | 1785..1838 | CDD:276965 | |||
| Kelch 11 | 1796..1843 | ||||
| Kelch 12 | 1852..1898 | ||||
| Plasmod_Pvs28 | <2189..2314 | CDD:283826 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2523..2564 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2817..2845 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1388 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D32816at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.820 | |||||