Protein Alignment dsd and Pafah1b3

DIOPT Version :10

• Sequence 1: NP_651571.3
• Gene: dsd / 43315
• FlyBaseID: FBgn0039528
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: NP_032802.1
• Gene: Pafah1b3 / 18476
• MGIID: 108414
• Length: 232
• Species: Mus musculus
• Alignment Length: 231
• Identity: 43/231 - (18%)
• Similarity: 67/231 - (29%)
• Gaps: 77/231 - (33%)

  Fly   343 WETVHPEDGSEVPDKRYGASTVMYGDKIFM-------------------YGGVVKGHGISNELWA 388
            |.::|....::..||.  ...|..||.:..                   :|  :.|....:.||.
Mouse    24 WMSLHHRFVADSKDKE--PEVVFIGDSLVQLMHQCEIWRELFSPLHALNFG--IGGDSTQHVLWR 84

  Fly   389 FDVS---------ARTWANISVRADPSCNATGGTTAMCGPLHVVGHTATLVPGYGDKNNYQYMVV 444
            .:..         ...|...:..:..:...|||..|:          ..||    :|...|..||
Mouse    85 LENGELEHIRPKIVVVWVGTNNHSHTAEQVTGGIKAI----------VQLV----NKLQPQARVV 135

  Fly   445 IFGHSPNYGYLNTVQEFNFASREWRIVPTTGYV------VKGGYGHSAAYDFLTEKVYVYGGIVS 503
            :.|..|...:.|.::|.|....|.......||.      ...|:.||             .|.:|
Mouse   136 VLGLLPRGQHPNPLREKNRQVNELVRAALAGYPRAHFLDADPGFVHS-------------DGTIS 187

  Fly   504 ESESSQVLSSRLYAYEPATRVWSLLSAAPSARLLHT 539
            ..:        :|.|...:|    |...|..|.||:
Mouse   188 HHD--------MYDYLHLSR----LGYTPVCRALHS 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dsd	NP_651571.3	CUB	86..212	CDD:238001
		NanM	<288..391	CDD:442289	11/66 (17%)
		KELCH repeat	308..349	CDD:276965	2/5 (40%)
		NanM	343..614	CDD:442289	43/231 (19%)
		KELCH repeat	358..420	CDD:276965	12/89 (13%)
		KELCH repeat	424..474	CDD:276965	12/49 (24%)
		KELCH repeat	482..531	CDD:276965	8/48 (17%)
		KELCH repeat	535..588	CDD:276965	3/5 (60%)
		PSI	821..870	CDD:396154
		EGF_Lam	948..994	CDD:238012
		EGF_Lam	995..1040	CDD:238012
Pafah1b3	NP_032802.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		PAF_acetylesterase_like	8..206	CDD:238858	40/224 (18%)