DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wdb and AT3G21650

DIOPT Version :9

Sequence 1:	NP_001368946.1	Gene:	wdb / 43312	FlyBaseID:	FBgn0027492	Length:	709	Species:	Drosophila melanogaster
Sequence 2:	NP_001326520.1	Gene:	AT3G21650 / 821719	AraportID:	AT3G21650	Length:	546	Species:	Arabidopsis thaliana

Alignment Length:	606	Identity:	252/606 - (41%)
Similarity:	348/606 - (57%)	Gaps:	83/606 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 KIFGWLRKTRNKRPVEILNSDFGEDGDEGVGEGKGQGAGEGGGAAASAAGGAADQFPVASVKNKA 162
            :|||.|    .::|.:.|.:|               ..||||                  |.|..
plant     4 QIFGKL----PRKPSKSLQND---------------SNGEGG------------------VNNSY 31

  Fly   163 GKLNTTQTA----TETAIDSNEPKSEKMSSGTFVDRIDPFAKRSLKKKGKKSQGSSRYRNSQDVE 223
            ...|::.|:    :.|:..|:.....::::||       .|..|:......:||.........|:
plant    32 YASNSSTTSISKPSSTSSKSSSASGSRVANGT-------LAPNSMSSNRNTNQGKKPLGGDAVVQ 89

  Fly   224 LQQLP---------PLKADCSSLEQEELFIRKLRQCCVSFDFMDPVTDLKGKEIKRAALNDLSTY 279
            ....|         |...|....|:..|||.||..|||.|||.||..:||.|||||..|.:|..|
plant    90 AGPFPSSGGVYEALPSFRDVPISEKPNLFIGKLSMCCVVFDFSDPSKNLKEKEIKRQTLLELVDY 154

  Fly   280 ITHGRGVLTEPVYPEIIRMISCNLFRTLPPSENPD-----FDPEEDDPTLEASWPHLQLVYEVFL 339
            :........:....|:.:|::.|||||.|.:.:..     .|.::::|:||.:|||:|:|||:.|
plant   155 VASVGFKFNDVSMQELTKMVAVNLFRTFPSANHESKILEIHDMDDEEPSLEPAWPHVQVVYEILL 219

  Fly   340 RFLESQDFQATIGKRVIDQKFVLQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNI 404
            ||:.|....|.:.||.||..|||:||:||||||.|||::|||:|||:||||:..|.:|||.||||
plant   220 RFVASPMTDAKLAKRYIDHSFVLKLLDLFDSEDQREREYLKTILHRVYGKFMVHRPYIRKAINNI 284

  Fly   405 FLRFIYETEHFNGVGELLEILGSIINGFALPLKAEHKQFLVKVLLPLHKVKCLSLYHAQLAYCIV 469
            |.|||.|||..||:.||||||||||||||||||.|||.||::.|:||||.||.|:||.||:||||
plant   285 FYRFISETEKHNGIAELLEILGSIINGFALPLKEEHKLFLLRALIPLHKPKCSSVYHQQLSYCIV 349

  Fly   470 QFLEKDPFLTEPVVRGLLKFWPKTCSQKEVMFLGEIEEILDVIDPPQFVKIQEPLFRQIAKCVSS 534
            ||:|||..|.:.|:|||||:||.|.|.||||||||:||:|:.....:|.:...||.||||:|::|
plant   350 QFVEKDFKLADTVIRGLLKYWPVTNSSKEVMFLGELEEVLEATQAAEFQRCMVPLSRQIARCLNS 414

  Fly   535 PHFQVAERALYLWNNEYAMSLIEENNAVIMPIMFPALYRISKEHWNQTIVALVYNVLKTFMEMNS 599
            .|||||||||:||||::..:||.:|:.|||||:||||.|.::.||||.:.:|..||.|...|::.
plant   415 SHFQVAERALFLWNNDHIRNLITQNHKVIMPIVFPALERNTRGHWNQAVQSLTINVRKVLCEIDQ 479

  Fly   600 KLFDELTSSYKAERQKEKKRERDREELWKKLHELESNRSSGRTAGGSATTSNSAASAASTSLQP- 663
            .||||..:.::.|...:.:.:..||..|::|.:|.::::         ..:|.|.      |.|
plant   480 VLFDECLAKFQVEEVNKTEVKAKRERTWQRLEDLATSKT---------VVTNEAV------LVPR 529

  Fly   664 -PSSAGLNSHQQQSNSGSSGS 683
             .||..|.:    |:|.|:||
plant   530 FVSSVNLTT----SSSESTGS 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wdb	NP_001368946.1	B56	235..633	CDD:396263	212/402 (53%)
AT3G21650	NP_001326520.1	B56	58..>122	CDD:421517	14/70 (20%)
AT3G21650	NP_001326520.1	B56	110..514	CDD:396263	212/403 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	507	1.000	Domainoid score	I70
eggNOG	1	0.900	-	-		E1_KOG2085
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	472	1.000	Inparanoid score	I350
OMA	1	1.010	-	-		QHG54502
OrthoDB	1	1.010	-	-		D890437at2759
OrthoFinder	1	1.000	-	-		FOG0000226
OrthoInspector	1	1.000	-	-		mtm982
orthoMCL	1	0.900	-	-		OOG6_100293
Panther	1	1.100	-	-	O	PTHR10257
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X167
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.880