Protein Alignment wdb and PPP2R5C

DIOPT Version :9

• Sequence 1: NP_001368946.1
• Gene: wdb / 43312
• FlyBaseID: FBgn0027492
• Length: 709
• Species: Drosophila melanogaster
• Sequence 2: XP_005267876.1
• Gene: PPP2R5C / 5527
• HGNCID: 9311
• Length: 584
• Species: Homo sapiens
• Alignment Length: 587
• Identity: 341/587 - (58%)
• Similarity: 410/587 - (69%)
• Gaps: 38/587 - (6%)

  Fly   147 GGAADQFPVASVKN-KAGKLNTTQTATETAIDSNEPKSEKMS----SGTFVDRIDPFAKRSLKKK 206
            |.:.::...|.::: ||||...:....:..::|.:....|.|    ..|...:|.....:.:.||
Human     3 GTSREELRKAELESPKAGKSGKSSKEGQDTVESEQISVRKNSLVAVPSTVSAKIKVPVSQPIVKK 67

  Fly   207 GKKSQGSSRYRNSQDVELQQLPPLKADCSSLEQEELFIRKLRQCCVSFDFM-DPVTDLKGKEIKR 270
            .|: |.|||:..|.:.|||:||.|| |....:||:|||:|||||||.|||: ||::|||.||:||
Human    68 DKR-QNSSRFSASNNRELQKLPSLK-DVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKR 130

  Fly   271 AALNDLSTYITHGRGVLTEPVYPEIIRMISCNLFRTLPPSENP---DFDPEEDDPTLEASWPHLQ 332
            |||:::..||||.|.|:|||:|||::.|.:.|:|||||||.||   :||||||:|||||:|||||
Human   131 AALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQ 195

  Fly   333 LVYEVFLRFLESQDFQATIGKRVIDQKFVLQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFI 397
            ||||.|||||||.|||..|.|:.||||||||||||||||||||||||||.|||||||||||||:|
Human   196 LVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYI 260

  Fly   398 RKQINNIFLRFIYETEHFNGVGELLEILGSIINGFALPLKAEHKQFLVKVLLPLHKVKCLSLYHA 462
            ||||||||.||||||||.||:.||||||||||||||||||.|||.||:||||||||||.||:||.
Human   261 RKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHP 325

  Fly   463 QLAYCIVQFLEKDPFLTEPVVRGLLKFWPKTCSQKEVMFLGEIEEILDVIDPPQFVKIQEPLFRQ 527
            |||||:|||||||..||||||..|||:||||.|.||||||.|:|||||||:|.:||||.||||||
Human   326 QLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ 390

  Fly   528 IAKCVSSPHFQVAERALYLWNNEYAMSLIEENNAVIMPIMFPALYRISKEHWNQTIVALVYNVLK 592
            :|||||||||||||||||.|||||.||||.:|.|.|:|||||:|||.||.|||:||..|:||.||
Human   391 LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALK 455

  Fly   593 TFMEMNSKLFDELTSSYKAERQKEKKRERDREELWKKLHELESNRSSGRTAGGSATTSNSAASAA 657
            .|||||.||||:.|..:|||:.|||.:.::|||.|.|:..|           ..|....:..|.|
Human   456 LFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENL-----------AKANPQYTVYSQA 509

  Fly   658 STSLQPPS----------------SAGLNSHQQQSNSGSSGSLSSGGAGGDNNPATTNAKIKQDK 706
            ||...|.:                :....:||.|.:......|:...:....:|.|..|.....:
Human   510 STMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCR 574

  Fly   707 AD 708
            ||
Human   575 AD 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wdb	NP_001368946.1	B56	235..633	CDD:396263	298/401 (74%)
PPP2R5C	XP_005267876.1	PLN00122	41..>153	CDD:215064	56/113 (50%)
		B56	94..497	CDD:279883	299/413 (72%)
		PLN00122	<402..502	CDD:215064	62/110 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2085
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54502
OrthoDB	1	1.010	-	-		D345293at33208
OrthoFinder	1	1.000	-	-		FOG0000226
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100293
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3
SonicParanoid	1	1.000	-	-		X167
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.760