DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wdb and ppp2r5a

DIOPT Version :9

Sequence 1:	NP_001368946.1	Gene:	wdb / 43312	FlyBaseID:	FBgn0027492	Length:	709	Species:	Drosophila melanogaster
Sequence 2:	NP_001072157.1	Gene:	ppp2r5a / 447953	XenbaseID:	XB-GENE-943352	Length:	476	Species:	Xenopus tropicalis

Alignment Length:	451	Identity:	337/451 - (74%)
Similarity:	391/451 - (86%)	Gaps:	4/451 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 MSSGTFVDRIDPFAKRSLKKKGK--KSQGSSRYR-NSQDVELQQLPPLKADCSSLEQEELFIRKL 247
            ||:.:..:::|.|.::|::|..:  :|||||::| ....|||..||||| |.:|.:|::||.:||
Frog     1 MSAISAAEKVDGFTRKSVRKAQRRGRSQGSSQFRGQGPPVELSPLPPLK-DATSNDQQDLFCQKL 64

  Fly   248 RQCCVSFDFMDPVTDLKGKEIKRAALNDLSTYITHGRGVLTEPVYPEIIRMISCNLFRTLPPSEN 312
            :||||.|||||.::|||.||||||.||:|..|::..||||.|..||:||:||..|:|||||||:|
Frog    65 QQCCVLFDFMDSISDLKSKEIKRATLNELVEYVSINRGVLVESAYPDIIKMICSNIFRTLPPSDN 129

  Fly   313 PDFDPEEDDPTLEASWPHLQLVYEVFLRFLESQDFQATIGKRVIDQKFVLQLLELFDSEDPRERD 377
            ||||||||:|||||||||:|||||.|||||||.|||.:|.||.:|||||.|||||||||||||||
Frog   130 PDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRFVDQKFVQQLLELFDSEDPRERD 194

  Fly   378 FLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVGELLEILGSIINGFALPLKAEHKQ 442
            |||||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||
Frog   195 FLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQ 259

  Fly   443 FLVKVLLPLHKVKCLSLYHAQLAYCIVQFLEKDPFLTEPVVRGLLKFWPKTCSQKEVMFLGEIEE 507
            ||:|||:|:|..|.|:|:|||||||:|||||||..||:||:|||||||||||||||||:||||||
Frog   260 FLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTDPVIRGLLKFWPKTCSQKEVMYLGEIEE 324

  Fly   508 ILDVIDPPQFVKIQEPLFRQIAKCVSSPHFQVAERALYLWNNEYAMSLIEENNAVIMPIMFPALY 572
            |||||:|.||.|||||||:||:|||||.||||||||||.|||||.:||||||...|:||||.:||
Frog   325 ILDVIEPTQFKKIQEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFGSLY 389

  Fly   573 RISKEHWNQTIVALVYNVLKTFMEMNSKLFDELTSSYKAERQKEKKRERDREELWKKLHEL 633
            :|||||||.||||||||||||.||||.|||||||.|||||||:|||:|.:|||||::|.:|
Frog   390 KISKEHWNPTIVALVYNVLKTLMEMNGKLFDELTGSYKAERQREKKKELEREELWRRLDDL 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wdb	NP_001368946.1	B56	235..633	CDD:396263	315/397 (79%)
ppp2r5a	NP_001072157.1	B56	53..431	CDD:366725	303/377 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D345293at33208
OrthoFinder	1	1.000	-	-		FOG0000226
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X167
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010