Protein Alignment CG5646 and SLC25A45

DIOPT Version :10

• Sequence 1: NP_651568.1
• Gene: CG5646 / 43311
• FlyBaseID: FBgn0039525
• Length: 303
• Species: Drosophila melanogaster
• Sequence 2: NP_872362.4
• Gene: SLC25A45 / 283130
• HGNCID: 27442
• Length: 288
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 104/302 - (34%)
• Similarity: 152/302 - (50%)
• Gaps: 35/302 - (11%)

  Fly     8 DFVAGCFGGACGVLVAHPLDTIKVWQQASNS--SVVTAIQQIYSRNNGVNGFYRGMFFPFISTGA 70
            :||||...||.|:::.||.||:||..|...:  .:|..:.:|| |:..:.||::||.||..|...
Human     5 EFVAGWISGALGLVLGHPFDTVKVRLQTQTTYRGIVDCMVKIY-RHESLLGFFKGMSFPIASIAV 68

  Fly    71 INSLLFGIYGNHLRQLRKVCHSDYQREQLEYHNMFLAGSVAGFVQSFIACPMELIKVRLQTATYY 135
            :||:|||:|.|.|..|....|.:.:.:...|.::||||...||:|::...|.:|||||||..|
Human    69 VNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYCLAPFDLIKVRLQNQT-- 131

  Fly   136 SDYLYGQRRTAFGT-----------FKRILKTDGISGLYRGLLPMMCRDVLPYGIYMLAYRQGVD 189
                  :.|...|:           ...|.:.:|..||:||...:..||....|||.:.| :|:
Human   132 ------EPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRDTPTVGIYFITY-EGL- 188

  Fly   190 YMDRRDFVRRRRSQSDGSSVNLLVTTLAGAWAGVISWVCVIPFDVVKTLMQAD--ENHKYRGIFH 252
                     .|:...:|.:.:.....:||.:||:.|||...|.|::|:.||.|  ....|:|:..
Human   189 ---------CRQYTPEGQNPSSATVLVAGGFAGIASWVAATPLDMIKSRMQMDGLRRRVYQGMLD 244

  Fly   253 CVRVQYRAYGWRSIFRGSWMLVARAVPFNAATFLGYEYALEW 294
            |:....|..|....|||..:..|||.|.||.|||.|||.|.|
Human   245 CMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYLLRW 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5646	NP_651568.1	Mito_carr	5..79	CDD:395101	30/72 (42%)
		Mito_carr	97..191	CDD:395101	32/104 (31%)
		Mito_carr	207..294	CDD:395101	34/88 (39%)
SLC25A45	NP_872362.4	Solcar 1	1..83		33/78 (42%)
		Mito_carr	2..77	CDD:395101	30/72 (42%)
		Mito_carr	95..186	CDD:395101	31/99 (31%)
		Solcar 2	97..191		32/112 (29%)
		Mito_carr	197..288	CDD:395101	35/90 (39%)
		Solcar 3	199..286		34/86 (40%)