DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG5646 and SLC25A15

DIOPT Version :10

Sequence 1:NP_651568.1 Gene:CG5646 / 43311 FlyBaseID:FBgn0039525 Length:303 Species:Drosophila melanogaster
Sequence 2:NP_055067.1 Gene:SLC25A15 / 10166 HGNCID:10985 Length:301 Species:Homo sapiens


Alignment Length:292 Identity:92/292 - (31%)
Similarity:129/292 - (44%) Gaps:21/292 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 DFVAGCFGGACGVLVAHPLDTIKVWQQASNS---SVVTAIQQIYSRNNGVNGFYRGMFFPFISTG 69
            |..||..||...||...|.||:||..|....   .:.....:.||: .|..|||:|.....|:..
Human    12 DLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQ-VGFRGFYKGTSPALIANI 75

  Fly    70 AINSLLFGIYGNHLRQLRKVCHSDYQREQLEYHNMFLAGSVAGFVQSFIACPMELIKVRLQTATY 134
            |.||:||..||...:.:|||...|.|.:..:..|. .|||.|....:.:.||.||:|.|||  |.
Human    76 AENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNA-AAGSFASAFAALVLCPTELVKCRLQ--TM 137

  Fly   135 Y----SDYLYGQRRTAFGTFKRILKTDGISGLYRGLLPMMCRDVLPYGIYMLAYRQGVDYMDRRD 195
            |    |..:...:.|.:...|.||:.||..|.|.||...:.|:|..|..:...|...      |.
Human   138 YEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELS------RS 196

  Fly   196 FVRRRRSQSDGSSVNLLVTTLAGAWAGVISWVCVIPFDVVKTLMQA-DENHKYRGIFHCVRVQYR 259
            |....||:.:...|.|:   |:|...|:..|:.|.|.|.:|:.:|. ..:.|..|.........:
Human   197 FFASGRSKDELGPVPLM---LSGGVGGICLWLAVYPVDCIKSRIQVLSMSGKQAGFIRTFINVVK 258

  Fly   260 AYGWRSIFRGSWMLVARAVPFNAATFLGYEYA 291
            ..|..:::.|....:.||.|.|.|.||.|||:
Human   259 NEGITALYSGLKPTMIRAFPANGALFLAYEYS 290

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5646NP_651568.1 Mito_carr 5..79 CDD:395101 26/73 (36%)
Mito_carr 97..191 CDD:395101 30/97 (31%)
Mito_carr 207..294 CDD:395101 25/86 (29%)
SLC25A15NP_055067.1 Solcar 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 7..91 28/79 (35%)
Mito_carr 9..94 CDD:395101 28/82 (34%)
Solcar 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 104..197 31/101 (31%)
Mito_carr <122..198 CDD:395101 26/83 (31%)
Mito_carr 205..296 CDD:395101 25/89 (28%)
Solcar 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 207..293 25/87 (29%)

Return to query results.
Submit another query.