Protein Alignment Klp98A and KIP3

DIOPT Version :9

• Sequence 1: NP_524532.2
• Gene: Klp98A / 43310
• FlyBaseID: FBgn0004387
• Length: 1265
• Species: Drosophila melanogaster
• Sequence 2: NP_011299.1
• Gene: KIP3 / 852655
• SGDID: S000003184
• Length: 805
• Species: Saccharomyces cerevisiae
• Alignment Length: 817
• Identity: 222/817 - (27%)
• Similarity: 339/817 - (41%)
• Gaps: 229/817 - (28%)

  Fly     2 SSLKVAVRVRPFNSREIDM----------------DAQLIMEMEN-----------------KKT 33
            ||:.||:|||||.|.|...                |:.||:.|.|                 |:.
Yeast     9 SSIVVAIRVRPFTSMEKTRLVNEASGAEANFPGLGDSSLILPMSNNSDSDIDIDAEEGSTRSKRN 73

  Fly    34 RLLKPR------------------------------------LQSIR------DAGRDNHHDFTF 56
            .||:.:                                    |.|:|      .|...|:.:.|.
Yeast    74 SLLRRKVIRPEGIRKIVDCVDDRMLIFDPADRNPLNKVSDQVLNSMRARATKATASSINNSNATN 138

  Fly    57 DYS----------YWSFDAEDPHFATQEQVYSDLGNDVVDCAYEGYNACVFAYGQTGSGKTFTMM 111
            .:|          .:.||......::|.:||.:..:.::|...:|:|:.|||||.||.|||:|:.
Yeast   139 KFSSQRRRHGGEIKFVFDKLFDETSSQARVYKETTSPLLDSVLDGFNSTVFAYGATGCGKTYTVS 203

  Fly   112 GTPNNPGLIPRICEELFARMRVGQESGTGYRTHASYLEIYNERVKDLLAAQSTGHGLRVREHRSL 176
            |||:.||:|....||||.:: ...:....:....|||||||||::|||..::....|.:||....
Yeast   204 GTPSQPGIIFLAMEELFNKI-TDLKDEKDFEISLSYLEIYNERIRDLLKPETPSKRLVIREDTQN 267

  Fly   177 GPYVENLSQHAVSDFDEIQECIARGNAQRTTASTNMNDTSSRSHAIFTITFVQAVFMNDMPSE-T 240
            ...|.|||.|..:..:::.:.:.:||..|||:.|..|:.||||||:..|..:|...:.|:.|: |
Yeast   268 HIKVANLSYHHPNTVEDVMDLVVQGNINRTTSPTEANEVSSRSHAVLQIHIMQTNKLVDLTSQHT 332

  Fly   241 VSKIHLVDLAGSERANATGATGQRLKEGAHINKSLVTLGSVISALAEQTGGGHNSSSSALATTPN 305
            .:.:.::||||||||.||...|.||.|||:||:||:.||:.|:||....|
Yeast   333 FATLSIIDLAGSERAAATRNRGIRLHEGANINRSLLALGNCINALCLNDG--------------- 382

  Fly   306 GASKRVLYIPYRDSILTWLLKDSLGGNSKTIMIAALSPADCNYSETLSTLRYANRAKNIINKPTV 370
               .|..:||||||.||.|||.|||||.||:||..:||:..:|.|||:||:||||||.|..|...
Yeast   383 ---SRSCHIPYRDSKLTRLLKFSLGGNCKTVMIVCISPSSSHYDETLNTLKYANRAKEIKTKIIR 444

  Fly   371 NED-------TNVKLIRELREEINKLKSMLAGDIHSLQPSLKVLADLQKKEAQEKVLTE------ 422
            |:.       :.:|:|.|.:.:|.:|:     :......|||:......||..:..:.|
Yeast   445 NQQSLSRHVGSYLKMITEQKRQIEELR-----EREEKMISLKLTKYKLNKEKIQLAINECVNRVQ 504

  Fly   423 ---EWTEKWKVAQSILQEQKSLGLRKSGVGVVLDSEMPHLI------------------------ 460
               ...|.::||:::    |||.|.|.....::..|:.:||
Yeast   505 QTYAGVETYQVAKTL----KSLILCKRRFLQMVKLEVDNLILLFEREESTAAEMQPVISNCRMIS 565

  Fly   461 -----GIHN-----DVTT----------GVTLYSLKEGETRIGSEDADVAQDIELAGDGIRAQHC 505
                 .||.     |.|.          .:.|..|:|      .||.|...|:
Yeast   566 GQLYNKIHELEMKFDETDTLSSVIHQVHSIDLNKLRE------MEDWDETYDL------------ 612

  Fly   506 SIFLKGGVVTLHPWPLAQCWVNAHLIDEPKQISQGDIILLGRTNIFRF------NNPAEAAKLRK 564
             ::|:..:..:......:..||:.::.| |.:|..     |..:.|:|      |.......:.:
Yeast   613 -VYLESCLNQISELQRNEILVNSSIMTE-KLMSDP-----GLNSRFKFLSKWLMNRTPNIESIIQ 670

  Fly   565 DLSR--SQLDMSRLSLITSSKENLLTCSI----YSDEDGASPYKRPERQYYPQR----------- 612
            ||..  .:.:....:.|.:...|....:|    .:..|.|.|.:..:||.:.|:
Yeast   671 DLVHIDEEFESFARTFIANPDSNFTNTNINIINTTAADLAVPAETLQRQNFSQKKVKWTSPDLSP 735

  Fly   613 -PMSRDDPELQDENRKILDTIENALKQLNVERVQMHD 648
             ||....|||:.|..:..|.|.:.:.      |.|.|
Yeast   736 SPMIEPQPELEPELHQDQDAIASEVD------VSMQD 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp98A	NP_524532.2	KISc_KIF1A_KIF1B	2..371	CDD:276816	156/454 (34%)
		KISc	3..371	CDD:214526	155/453 (34%)
		Kinesin_assoc	370..478	CDD:292801	29/167 (17%)
		FHA	456..555	CDD:238017	22/148 (15%)
		PX_KIF16B_SNX23	1131..1259	CDD:132784
KIP3	NP_011299.1	KISc_KIP3_like	82..438	CDD:276821	135/374 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910