Protein Alignment Klp98A and ZCF125

DIOPT Version :10

• Sequence 1: NP_524532.2
• Gene: Klp98A / 43310
• FlyBaseID: FBgn0004387
• Length: 1265
• Species: Drosophila melanogaster
• Sequence 2: NP_564744.1
• Gene: ZCF125 / 842245
• AraportID: AT1G59540
• Length: 823
• Species: Arabidopsis thaliana
• Alignment Length: 975
• Identity: 251/975 - (25%)
• Similarity: 418/975 - (42%)
• Gaps: 231/975 - (23%)

  Fly     1 MSSLKVAVRVRPFNSREIDMDAQLIMEMENKKTRLLKPRLQSIRDAGRDNHHDFTFDYSYWSFDA 65
            |..:.|||||||    ....:...:.::|:.:..|.|.....|..|  .:..|..||.|
plant     1 MEKICVAVRVRP----PAPENGASLWKVEDNRISLHKSLDTPITTA--SHAFDHVFDES------ 53

  Fly    66 EDPHFATQEQVYSDLGNDVVDCAYEGYNACVFAYGQTGSGKTFTMMGTPNNPGLIPRICEELFAR 130
                 :|...||..|..|::..|.||:|...||||||.|||||||.|:..:||:|.|...::|.|
plant    54 -----STNASVYELLTKDIIHAAVEGFNGTAFAYGQTSSGKTFTMTGSETDPGIIRRSVRDVFER 113

  Fly   131 MRVGQESGTGYRTHASYLEIYNERVKDLLAAQSTGHGLRVREHRSLGPYVENLSQHAVSDFDEIQ 195
            :.:  .|...:....||:|||||.:.||||.::  ..|::.||...|.:|..|.:..|||.::|.
plant   114 IHM--ISDREFLIRVSYMEIYNEEINDLLAVEN--QRLQIHEHLERGVFVAGLKEEIVSDAEQIL 174

  Fly   196 ECIARGNAQRTTASTNMNDTSSRSHAIFTITFVQAVFMNDMPSET--VSKIHLVDLAGSERANAT 258
            :.|..|...|....||||..|||||.||.:. :::...::..|:.  ||.::|||||||||...|
plant   175 KLIDSGEVNRHFGETNMNVHSSRSHTIFRMV-IESRGKDNSSSDAIRVSVLNLVDLAGSERIAKT 238

  Fly   259 GATGQRLKEGAHINKSLVTLGSVISALAEQTGGGHNSSSSALATTPNGASKRVLYIPYRDSILTW 323
            ||.|.||:||.:|||||:.||:||:.|::.|                   |...:||||||.||.
plant   239 GAGGVRLQEGKYINKSLMILGNVINKLSDST-------------------KLRAHIPYRDSKLTR 284

  Fly   324 LLKDSLGGNSKTIMIAALSPADCNYSETLSTLRYANRAKNIINKPTVNED-TNVKLIRELREEIN 387
            :|:.:||||:||.:|..::|.:.:..|:..||::|:|||.|.|...|||. |:..|::..:.||.
plant   285 ILQPALGGNAKTCIICTIAPEEHHIEESKGTLQFASRAKRITNCAQVNEILTDAALLKRQKLEIE 349

  Fly   388 KLKSMLAGDIHS--LQPSLKVLADLQKKEAQE----KVLTEEWTEKWKVAQSILQEQKSLGLRKS 446
            :|:..|.|. |:  |:..:..|::...|...|    |...||...|.|..::.::||:.
plant   350 ELRMKLQGS-HAEVLEQEILNLSNQMLKYELECERLKTQLEEEKRKQKEQENCIKEQQM------ 407

  Fly   447 GVGVVLDSEMPHLIGIHNDVTTGVTLYSLKEGETRIGSEDADVAQDIELAGDGIRAQHCSIFLKG 511
                       .:..::|.||..    ..|..:    |||..:::.   ..||:    |::....
plant   408 -----------KIENLNNFVTNS----DFKRNQ----SEDFIISRK---TPDGL----CNVNDTS 446

  Fly   512 GVVTLHPWPLAQCWVNAHLIDEPKQISQGDIILLGRTNIFRFNNPAEAAKLRKDLSRSQLDMSRL 576
            .|      |...|:         |..|:..::.       |.||.:              .:|..
plant   447 DV------PGTPCF---------KSASRSFVVA-------RSNNYS--------------GLSDF 475

  Fly   577 SLITSSKENLLTCSIYSDEDGASPYKR------PERQYYP-----QRPMSRDDPELQDENRKILD 630
            |.:..|..::      :|||......:      .:.|:.|     ..|:|....|...||...::
plant   476 SPMVHSLGDV------ADEDTWMKLNKGFVADLDQIQFTPAVKCQPTPLSIATTECPRENHSEVE 534

  Fly   631 TIENALKQLNVERVQMHDQYKTKV---RKLTEELIRLEQEEMDGLQL--------LNCRE--QEL 682
            .:::.::.|..|...:..::..:|   ..|.:|:..|:||.:...::        .||::  :::
plant   535 DLKSRIQLLTNENDSLQVKFNEQVLLSNNLMQEMSELKQETLTVKEIPNRLSESVANCKDVYKDV 599

  Fly   683 IARKDMLLWEKNNEKVQI-----DIVCRQISAFQTQ----LDSKK---------RDFSEYVAKEL 729
            |.....|:.:|.:....:     :|....::..:||    :|.:|         .|..|.:...|
plant   600 IVTMKSLITDKESPTANLLLGTTEITTSLLATLETQFSMIMDGQKTGSSIDHPLSDHWETLRVNL 664

  Fly   730 QE-----LQDCGKLDEM------GMK---IEEGTPLNDELLLQVSDSLDLFAAQFIKDTVRRNNE 780
            :.     |.|....||.      |.:   :|| ..|..||::                 ::....
plant   665 KNTTTLLLSDAQAKDEFLNSHNKGQETAALEE-KKLKSELII-----------------IKERYN 711

  Fly   781 EIRK---LDEQIAEKERILNASTTKIAKVDETMLE--------IQAQLERLRLERAESEAESQAM 834
            |:.|   ||:|:.|..|   .|..|:.|..:.:.|        |....:|||:..::.|...:.:
plant   712 ELEKELCLDKQLLEASR---ESHEKLIKEVQFLKEERDSLDRKISQSTQRLRVIASDKENALKDL 773

  Fly   835 RA---KKQNMKLQLGNKSMSTSTSTNEADDVSKSDTYETCDTFHTAQSNLSLVSSPTITEGQQSP 896
            ..   ::::|:.::  |.:|.:.:|.....||          ||   |.:........|:..::|
plant   774 NVEVKRRKDMEEEI--KHISIAFATRHKSFVS----------FH---SEIKSKMQKLTTQNSKAP 823

  Fly   897  896
            plant   824  823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp98A	NP_524532.2	KISc_KIF1A_KIF1B	2..371	CDD:276816	139/370 (38%)
		Kinesin_assoc	370..478	CDD:465047	26/114 (23%)
		FHA_KIF16	449..556	CDD:438760	17/106 (16%)
		SMC_N	624..>864	CDD:481474	54/298 (18%)
		PX_KIF16B_SNX23	1131..1259	CDD:132784
ZCF125	NP_564744.1	KISc_CENP_E	3..325	CDD:276825	137/362 (38%)
		Cortex-I_coil	711..787	CDD:312712	17/78 (22%)