Protein Alignment Klp98A and AT3G12020

DIOPT Version :10

• Sequence 1: NP_524532.2
• Gene: Klp98A / 43310
• FlyBaseID: FBgn0004387
• Length: 1265
• Species: Drosophila melanogaster
• Sequence 2: NP_001189866.1
• Gene: AT3G12020 / 820376
• AraportID: AT3G12020
• Length: 1044
• Species: Arabidopsis thaliana
• Alignment Length: 1067
• Identity: 270/1067 - (25%)
• Similarity: 442/1067 - (41%)
• Gaps: 241/1067 - (22%)

  Fly     3 SLKVAVRVRPFNSREIDMDAQLIMEMENKKTRLLKPRLQSIRDAGRDNHHDFTFDYSYWSFDAED 67
            ::.|.||.||.:.|||....::....:.:..         :|     |.|:.|..|:|      |
plant    69 NVTVTVRFRPLSPREIRQGEEVAWYADGETI---------VR-----NEHNPTIAYAY------D 113

  Fly    68 PHF---ATQEQVYSDLGNDVVDCAYEGYNACVFAYGQTGSGKTFTMMGTPNNPGLIPRICEELFA 129
            ..|   .|...||....:.||:.|.||.|..:||||.|.||||.||.|...:||:||...::.|:
plant   114 RVFGPTTTTRNVYDIAAHHVVNGAMEGINGTIFAYGVTSSGKTHTMHGDQRSPGIIPLAVKDAFS 178

  Fly   130 RMRVGQES-GTGYRTHASYLEIYNERVKDLLAAQSTGHGLRVREHRSLGPYVENLSQHAVSDFDE 193
               :.||: ...:....||:|||||.|.|||  ...||.||:||.:. |.:||.:.:..|.....
plant   179 ---IIQETPNREFLLRISYMEIYNEVVNDLL--NPAGHNLRIREDKQ-GTFVEGIKEEVVLSPAH 237

  Fly   194 IQECIARGNAQRTTASTNMNDTSSRSHAIFTITFVQAVFMNDMPSETV--SKIHLVDLAGSERAN 256
            ....||.|..||...|||.|..|||||.|||:|...:...:....|.|  |:::|||||||| ::
plant   238 ALSLIAAGEEQRHVGSTNFNLLSSRSHTIFTLTIESSPLGDKSKGEAVHLSQLNLVDLAGSE-SS 301

  Fly   257 ATGATGQRLKEGAHINKSLVTLGSVISALAEQTGGGHNSSSSALATTPNGASKRVLYIPYRDSIL 321
            ....:|.|.|||::|||||:|||:|||.|.:                     .|..::|||||.|
plant   302 KVETSGVRRKEGSYINKSLLTLGTVISKLTD---------------------VRASHVPYRDSKL 345

  Fly   322 TWLLKDSLGGNSKTIMIAALSPADCNYSETLSTLRYANRAKNI-----INKPTVNEDTNVKL--- 378
            |.:|:.||.|:.:..:|..::||..:..||.:||::|:|||:|     .|| .::|.:.:|.
plant   346 TRILQSSLSGHDRVSLICTVTPASSSSEETHNTLKFAHRAKHIEIQAEQNK-IIDEKSLIKKYQR 409

  Fly   379 -IRELREEINKLKSML----------AGDIHSLQPSL-----KVLADLQKKEAQEKVLTEEWTEK 427
             ||:|:||:.:||..:          |.||..|:..|     |:.:.|:::|..:..|.......
plant   410 EIRQLKEELEQLKQEIVPVPQLKDIGADDIVLLKQKLEDGQVKLQSRLEEEEEAKAALLSRIQRL 474

  Fly   428 WKVAQSILQEQKSLGL-------RKSGVGVVLDSEMPHLIGIHNDVTTG--VTLYSLKEGETRIG 483
            .|:.....:..::..|       |:...|   :.|:.:|.....|:...  :.||...||...|
plant   475 TKLILVSTKNPQASRLPHRFNPRRRHSFG---EEELAYLPYKRRDMMDDEQLDLYVSVEGNHEI- 535

  Fly   484 SEDADVAQDIELAGDGI--------RAQHCSIFLKGGVVTLHPWPLAQCWVNAHLIDEPKQISQG 540
             .|....::.:....|:        |....|...:..||..:..|.......:||..| .::|:|
plant   536 -RDNAYREEKKTRKHGLLNWLKPKKRDHSSSASDQSSVVKSNSTPSTPQGGGSHLHTE-SRLSEG 598

  Fly   541 DIILLGRTNIFRFNNPAEAAKLRKDLSR------------SQLDMSRLSLITSSKENLLTCSI-- 591
            ..::      .:.:.|.|..:..:|.|.            .:||:.|......|:|..|..|.
plant   599 SPLM------EQLSEPREDREALEDSSHEMEIPETSNKMSDELDLLREQKKILSEEAALQLSSLK 657

  Fly   592 -YSDEDGASPYKRPERQYYPQRPMSRDDPELQDE-----NRKILD---TIENALKQLNVER--VQ 645
             .|||...||   ...:...:..:..||.:.:::     .|:|:|   |...||.:.::.:  .:
plant   658 RMSDEAAKSP---QNEEINEEIKVLNDDIKAKNDQIATLERQIMDFVMTSHEALDKSDIMQAVAE 719

  Fly   646 MHDQYKTKVRKLTEELIRL---------EQEEMDGLQLLNCREQELIARKDMLLWEKNNEKVQID 701
            :.||...|..:|  |:|.|         ..|..||..:...|   |.......|....|:...:.
plant   720 LRDQLNEKSFEL--EVIELFLFMQFFFIYAEVRDGFAIAWIR---LFILAQYYLSSYLNKVSSVY 779

  Fly   702 IVCRQISAFQTQLDSK-----------------KRDFSEYVAKELQELQ-DCGKLDEMGMKIEEG 748
            |:..|.|..||.|..|                 |...:..:.:.|.|.. :|..|.|....:::
plant   780 IIKYQYSKRQTILTMKLMVCSTLFSHSSSCLQVKAADNRIIQQTLNEKTCECEVLQEEVANLKQ- 843

  Fly   749 TPLNDELLLQVSDSLDLFAAQFIKDTVRRNNEEI-----------RKLDEQIAEKERILNASTTK 802
                     |:|::|:|.....||: ::::.:|:           |||.|:.:..:.:.:|:..:
plant   844 ---------QLSEALELAQGTKIKE-LKQDAKELSESKEQLELRNRKLAEESSYAKGLASAAAVE 898

  Fly   803 IAKVDETMLEIQAQLERLRLE------------------------RAES-----EAESQAMRAKK 838
            :..:.|.:.::..|.|||..|                        |.||     |.:|.:|..|:
plant   899 LKALSEEVAKLMNQNERLAAELATQKSPIAQRNKTGTTTNVRNNGRRESLAKRQEHDSPSMELKR 963

  Fly   839 Q---------NMKLQLGNKSMSTSTSTNEADDVSKSDTYETCDTFHTAQSNL-SLVSSPTITEGQ 893
            :         :.:..||.|....:......::..:.:.|     .....:|: .|||....::|.
plant   964 ELRMSKERELSYEAALGEKEQREAELERILEETKQREAY-----LENELANMWVLVSKLRRSQGA 1023

  Fly   894 QSPLSNCSCDAEDEAEDTRKDDLSGSS 920
            .|.:|       |...:||:.:.:..|
plant  1024 DSEIS-------DSISETRQTEQTEGS 1043

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp98A	NP_524532.2	KISc_KIF1A_KIF1B	2..371	CDD:276816	137/378 (36%)
		Kinesin_assoc	370..478	CDD:465047	27/135 (20%)
		FHA_KIF16	449..556	CDD:438760	21/116 (18%)
		SMC_N	624..>864	CDD:481474	61/325 (19%)
		PX_KIF16B_SNX23	1131..1259	CDD:132784
AT3G12020	NP_001189866.1	KISc_CENP_E	69..388	CDD:276825	134/366 (37%)
		SMC_prok_B	<372..>1041	CDD:274008	143/712 (20%)