Protein Alignment Klp98A and AT3G10180

DIOPT Version :10

• Sequence 1: NP_524532.2
• Gene: Klp98A / 43310
• FlyBaseID: FBgn0004387
• Length: 1265
• Species: Drosophila melanogaster
• Sequence 2: NP_187629.3
• Gene: AT3G10180 / 820180
• AraportID: AT3G10180
• Length: 1273
• Species: Arabidopsis thaliana
• Alignment Length: 1324
• Identity: 316/1324 - (23%)
• Similarity: 527/1324 - (39%)
• Gaps: 365/1324 - (27%)

  Fly     1 MSSLKVAVRVRPFNSREIDMDAQLIMEMENKKTRLLKPRLQSIRDAGRDNHHDFTFDYSYWSFDA 65
            |..:.|:||.||.:|             |:.||...|....||   ...||....|:     ||.
plant     1 MERIHVSVRARPLSS-------------EDAKTSPWKISSDSI---FMPNHSSLAFE-----FDR 44

  Fly    66 EDPHFATQEQVYSDLGNDVVDCAYEGYNACVFAYGQTGSGKTFTMMGTPNNPGLIPRICEELFAR 130
            .........|||.....::|..|..|:|..|||||||.||||.||.|:|..||:||....:||.
plant    45 IFREDCKTVQVYEARTKEIVSAAVRGFNGTVFAYGQTNSGKTHTMRGSPIEPGVIPLAVHDLFD- 108

  Fly   131 MRVGQESGTGYRTHASYLEIYNERVKDLLAAQSTGHGLRVREHRSLGPYVENLSQHAVSDFDEIQ 195
             .:.|::...:....||||||||.:.||||.:.  ..|::.|:...|.:|..|.:..|:...::.
plant   109 -TIYQDASREFLLRMSYLEIYNEDINDLLAPEH--RKLQIHENLEKGIFVAGLREEIVASPQQVL 170

  Fly   196 ECIARGNAQRTTASTNMNDTSSRSHAIFTITFVQAVFM------NDMPSETVSKIHLVDLAGSER 254
            |.:..|.:.|....||||..|||||.||.:.......|      |...:..||.::|||||||||
plant   171 EMMEFGESHRHIGETNMNLYSSRSHTIFRMIIESRQKMQDEGVGNSCDAVRVSVLNLVDLAGSER 235

  Fly   255 ANATGATGQRLKEGAHINKSLVTLGSVISALAE--QTGGGHNSSSSALATTPNGASKRVLYIPYR 317
            |..|||.|.|||||:||||||:|||:||..|:|  :|.|||                    :|||
plant   236 AAKTGAEGVRLKEGSHINKSLMTLGTVIKKLSEGVETQGGH--------------------VPYR 280

  Fly   318 DSILTWLLKDSLGGNSKTIMIAALSPADCNYSETLSTLRYANRAKNIINKPTVNED-TNVKLIRE 381
            ||.||.:|:.:||||:.|.:|..::.|..:..||.|:|::|:||..:.|...|||. |:..|::.
plant   281 DSKLTRILQPALGGNANTAIICNITLAPIHADETKSSLQFASRALRVTNCAHVNEILTDAALLKR 345

  Fly   382 LREEINKLKSML--AGDIHSLQPSLKVLADLQKKEAQ-EKVLTEEWTEKWKVAQ--SILQEQ-KS 440
            .::||.:|:|.|  :...||.:..|.:...|.|.|.: |::..|...||...||  .:|||| |.
plant   346 QKKEIEELRSKLKTSHSDHSEEEILNLRNTLLKSELERERIALELEEEKKAQAQRERVLQEQAKK 410

  Fly   441 LGLRKSGVGVVLDS------EMPHL----------IG-IHNDVTT---------GVTLYSLK-EG 478
            :   |:...:||.|      |..|.          || :..|.|:         |.:|.|.: |.
plant   411 I---KNLSSMVLLSNRDEKREQDHFKKGKRRDTWCIGKLSRDSTSEDQSNVLSRGSSLESARSER 472

  Fly   479 ET---------------RIGSEDAD-VAQDIELAGDGIRAQHCSIFLKGGVVTLHPWPLAQCWVN 527
            ||               .|..||.| :...:|   |.:....|::                  ||
plant   473 ETGPLLPFSELVNEPLYNINEEDEDSIEGTLE---DSVLPDPCAL------------------VN 516

  Fly   528 AHLIDEPKQISQGDIILLGRTNIFRFNNPAEAAKLRKD----LSRSQLDMSRLSLITSSKENLLT 588
            .....:|....:..:::  ...:.|.....||..|:.:    :|..|::..::.|
plant   517 VTSRKKPSIKQKNPVVV--ENELDRIQREYEALLLQYETERIISEIQIECLKVKL---------- 569

  Fly   589 CSIYSDEDGAS---PYKRPE---RQYYPQRPMSRDDPELQDENRKILDTIENALKQLNVERVQMH 647
                 .|||.|   ..|:.|   ..:..:..::..|||      .||     .:|||. |::.|.
plant   570 -----GEDGLSGDAKCKQSEVVGNVHCEEHVVNLRDPE------AIL-----LIKQLQ-EKINML 617

  Fly   648 DQYKTKVRKLTEELIRLE--------------QEEMDGLQLLNCREQELIARKDMLLWEKNNEKV 698
            :..|:...:..::|:.:.              |||:..     .||:..:||:.::    :.|..
plant   618 ELEKSSSNRNLDDLVMVATEQNICAREKFAEIQEEIHA-----AREEAQVAREQLV----SKESE 673

  Fly   699 QIDIVCRQISAF---QTQLDSKKRDFSEYVAKELQELQDCGKLDEMGMKIEEG-------TPLND 753
            .||::....::.   .|:::..:.:|.:|.|          .::.:...:.||       :||..
plant   674 VIDVINENFNSLVNVATEIEVLESEFQKYKA----------SVETISSVMNEGLQDFAFFSPLIH 728

  Fly   754 ELLLQVSDSLDLFAAQFIKDTVRRNNEEIRKLDE-QIAEKERILNASTTKIAKVDETMLEIQAQL 817
            :..|            |::.:..:::..|..... |.:.|:::|:....|:. :.|....:|:|:
plant   729 DFTL------------FVRQSSEQHDSLINSYQTVQSSLKKKVLDVENEKLL-LQEQCAGLQSQI 780

  Fly   818 ERLRLERAESEAESQAMRAKKQNMK---------LQLGNKSMSTSTSTNEADDVSKSDTYETCDT 873
            |.|..|..:.|...:.:....::.:         |:....|:|:|:...|.:::.| |..:|...
plant   781 EELNQEAQKHETSLKMLSEHHESERSDLLSHIECLEKDIGSLSSSSLAKEKENLRK-DFEKTKTK 844

  Fly   874 FHTAQSNL-SLVSSPTITEGQQSPLSNCSCDAEDEAEDTRKDDLSGSSEETSRTCTAGPSSGSGS 937
            ....:|.| :.:...|..|.:::       .||.|.:...........:.:.:...||.
plant   845 LKDTESKLKNSMQDKTKLEAEKA-------SAERELKRLHSQKALLERDISKQESFAGK------ 896

  Fly   938 GSVGIGGSGSAPSCTPSSQAIMSDSGVCLDSRNQAILQNGHLNNYKQ------------------ 984
                                 ..||.:...|.||::.:     .:||
plant   897 ---------------------RRDSLLVERSANQSLQE-----EFKQLEVLAFEMETTIASLEEE 935

  Fly   985 -AVRTSDEDTGSCSSCELG----------RHSDVARPYCPLHSLRRKIAAQKALI------MKNL 1032
             |....:::...|.:..||          .||:.     .|..|:..:...|..:      .:.|
plant   936 LAAERGEKEEALCRNDGLGSEITDLTEKLEHSNT-----KLEHLQNDVTELKTRLEVSSSDQQQL 995

  Fly  1033 ETDL-----NKAQLDEHIAD----------------------LQDLQRRY--IQME---QEMLQS 1065
            ||::     .|.:|..|:|:                      :::..|.|  ||:|   :||.:.
plant   996 ETNVKQLLEEKEELAMHLANSLLEMEEEKAIWSSKEKALTEAVEEKIRLYKNIQIESLSKEMSEE 1060

  Fly  1066 VQDLEA-HAQC--------CADERSGMERQYELASSI--------MRSS-VMSPTSME--ESTSQ 1110
            .::||: ..:|        |::|.:..:::..|..|:        :||: .:|..|.|  :|...
plant  1061 KKELESCRLECVTLADRLRCSEENAKQDKESSLEKSLEIDRLGDELRSADAVSKQSQEVLKSDID 1125

  Fly  1111 IYSPSMTRSCPSMREFPEGEHFIT 1134
            |....:..:|.....|.....::|
plant  1126 ILKSEVQHACKMSDTFQREMDYVT 1149

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp98A	NP_524532.2	KISc_KIF1A_KIF1B	2..371	CDD:276816	141/376 (38%)
		Kinesin_assoc	370..478	CDD:465047	40/141 (28%)
		FHA_KIF16	449..556	CDD:438760	26/149 (17%)
		SMC_N	624..>864	CDD:481474	46/273 (17%)
		PX_KIF16B_SNX23	1131..1259	CDD:132784	1/4 (25%)
AT3G10180	NP_187629.3	KISc_CENP_E	4..327	CDD:276825	140/367 (38%)
		sbcc	<335..904	CDD:129705	127/688 (18%)
		SMC_prok_B	644..>1268	CDD:274008	96/583 (16%)