Protein Alignment Klp98A and kif1ca

DIOPT Version :10

• Sequence 1: NP_524532.2
• Gene: Klp98A / 43310
• FlyBaseID: FBgn0004387
• Length: 1265
• Species: Drosophila melanogaster
• Sequence 2: XP_068077671.2
• Gene: kif1ca / 570771
• ZFINID: ZDB-GENE-200303-1
• Length: 1185
• Species: Danio rerio
• Alignment Length: 1075
• Identity: 354/1075 - (32%)
• Similarity: 518/1075 - (48%)
• Gaps: 289/1075 - (26%)

  Fly     2 SSLKVAVRVRPFNSREIDMDAQLIMEMENKKTRLLKPRLQSIRDAGRDNHHDFTFDYSYWSFDA- 65
            ||:|||||||||||||.:..|:.:::|::|.|.:..|:      ..:::..:|||||||||..:
Zfish     4 SSVKVAVRVRPFNSRETNRGAKCVIQMQDKSTCITNPK------QPKESPKNFTFDYSYWSHSSE 62

  Fly    66 EDPHFATQEQVYSDLGNDVVDCAYEGYNACVFAYGQTGSGKTFTMMG--TPNNPGLIPRICEELF 128
            |||.||:|.:||.|:|.:::..|:||||.|:|||||||:||::||||  .|...|:||::||:||
Zfish    63 EDPSFASQRKVYQDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQDPGQQGIIPQMCEDLF 127

  Fly   129 ARMRVGQESGTGYRTHASYLEIYNERVKDLLAAQSTGHGLRVREHRSLGPYVENLSQHAVSDFDE 193
            .:.....:....:....||:|||.|||:|||..:|.| .||||||..:|||||:||:.||:::.:
Zfish   128 RQTAENTDPDLSFSVEVSYMEIYCERVRDLLNPKSKG-ALRVREHPIMGPYVEDLSKMAVTNYSD 191

  Fly   194 IQECIARGNAQRTTASTNMNDTSSRSHAIFTITFVQ--AVFMNDMPSETVSKIHLVDLAGSERAN 256
            |.:.:..||..||.|:||||:|||||||:|||.|.|  ...|..:.:|.||||.||||||||||:
Zfish   192 IADLMDTGNKARTVAATNMNETSSRSHAVFTILFTQHRHDHMTSLDTEKVSKISLVDLAGSERAD 256

  Fly   257 ATGATGQRLKEGAHINKSLVTLGSVISALAEQTGGGHNSSSSALATTPNGASK--RVLYIPYRDS 319
            ::||.|.||||||:|||||.|||.||||||:            :.:.|...||  |..:||||||
Zfish   257 SSGAKGMRLKEGANINKSLTTLGKVISALAD------------MVSPPQHGSKKRRSDFIPYRDS 309

  Fly   320 ILTWLLKDSLGGNSKTIMIAALSPADCNYSETLSTLRYANRAKNIINKPTVNEDTNVKLIRELRE 384
            :|||||:::|||||:|.|||||||||.||.|||||||||:|||.|.....:|||.|.:|:|||:|
Zfish   310 VLTWLLRENLGGNSRTAMIAALSPADINYEETLSTLRYADRAKQIKCNAVINEDPNARLVRELKE 374

  Fly   385 EINKLKSML------------------------AGDIHSLQPSLKVLAD---------------- 409
            |:|:||.:|                        .|:.|  ||||..:..
Zfish   375 EVNRLKELLLSQGLSNLITASGSETGHPALAGVLGEPH--QPSLSYVQSTSDAPMEGVTPTSPSE 437

  Fly   410 -LQKKEAQEKV---------LTEEWTEKWKVAQSILQEQKSL------GLRKSG--VGVVLDSEM 456
             :.|:||.|::         |.|.|.||.:..:.|.|:::||      .:::.|  |||....:.
Zfish   438 PISKEEAAERLKETEKIIAELNETWEEKLRKTEEIRQDRESLLAEMGVSVKEDGGTVGVFSPKKT 502

  Fly   457 PHLIGIHND-VTTGVTLYSLKEGETRIGSEDADVAQDIELAGDGIRAQHCSIFL------KGGVV 514
            |||:.::.| :.:...:|.:|:|.||:|.||.    ||.|:|..|:..|| :|.      ...||
Zfish   503 PHLVNLNEDPLMSECLIYYIKDGVTRVGQEDV----DIRLSGQFIKELHC-VFCSEINENNEVVV 562

  Fly   515 TLHPWPLAQCWVNAHLIDEPKQISQGDIILLGRTNIFRFNNPAEAAKLRKDLSRSQ--------- 570
            ||.|...|:.:||...:.|...:.||:.|::|:.::||||:| |.|:|.::.|.:|
Zfish   563 TLEPLVGAETYVNGKQVTEGVVLKQGNRIVMGKNHVFRFNHP-EQARLERERSATQEQQGEPVDW 626

  Fly   571 ----------------------------------------LDMSRL------------------- 576
                                                    |:..||
Zfish   627 SYAQKELLEKQGIDIKQEMEKRLQDLENQYRKEKEEADQILEQQRLYADSDSGDDSDKRSCEESW 691

  Fly   577 SLITSSKENL---------LTCSIYSDEDGASPYKRPERQYYPQRPMSRDDPELQDENRKILDTI 632
            .||:|.:|.|         ..|.:.|    :...:.|.|.|  |.|..|..|..|:...::  ::
Zfish   692 RLISSLREKLPANKMQSIVKKCGLPS----SGKRREPLRVY--QIPQRRRIPATQESKHRL--SV 748

  Fly   633 E----NALKQLNVERVQMHDQYKTKVRKLTEELIRLEQEEMDGLQLLNCREQELIARKDMLLWEK 693
            |    .|:|::..| |.:.|...|:             :|::.|.::..:|
Zfish   749 EELRTQAVKEICYE-VALGDFKHTR-------------QEIEALAIVRMKE-------------- 785

  Fly   694 NNEKVQIDIVCRQISAFQTQLDSKKRDFSEYVAKELQELQDCGKLDEMGMKIEEG---------- 748
                     :||.    ..|.|.::|:..:.|||::.|        .:|:..|||
Zfish   786 ---------LCRT----YCQKDPQERETWKSVAKDVCE--------TVGIGEEEGDREDRIAAAA 829

  Fly   749 ---------TPLNDELLLQVSDSLDLFAAQFIKDTVRRNNEEIRKLDEQIAEKERILNASTTKI- 803
                     |.:.| |...:....|:.  |.:|......:||||.|.:::.:.|:|........
Zfish   830 AVGGSEGGKTDMGD-LKAHIDKLTDIL--QEVKLQNNMKDEEIRSLRDRMVKMEKIFPVDVKGDD 891

  Fly   804 -------AKVDETMLEIQAQLERLRLERAE-----SEAESQAMRAKKQNMKLQLGNKSMSTSTST 856
                   |:|:|...::..:.|.....|..     .|......|.|..|.:......:..|..|.
Zfish   892 EDVEFGGARVEEPTAQVNRRNEDSGYRRGRHRWQYPEKYHDPKRRKGANNQPNNALYTPPTGHSQ 956

  Fly   857 NEADDVSKSDTYETCDTFHTAQ---SNLSLVSSPT 888
            |              :.|:||.   ||.|..|.|:
Zfish   957 N--------------NPFNTASSRPSNPSFNSQPS 977

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp98A	NP_524532.2	KISc_KIF1A_KIF1B	2..371	CDD:276816	200/375 (53%)
		Kinesin_assoc	370..478	CDD:465047	43/166 (26%)
		FHA_KIF16	449..556	CDD:438760	39/113 (35%)
		SMC_N	624..>864	CDD:481474	48/275 (17%)
		PX_KIF16B_SNX23	1131..1259	CDD:132784
kif1ca	XP_068077671.2	None