Protein Alignment Klp98A and kif19

DIOPT Version :10

• Sequence 1: NP_524532.2
• Gene: Klp98A / 43310
• FlyBaseID: FBgn0004387
• Length: 1265
• Species: Drosophila melanogaster
• Sequence 2: XP_005156460.1
• Gene: kif19 / 565913
• ZFINID: ZDB-GENE-080215-2
• Length: 1015
• Species: Danio rerio
• Alignment Length: 1132
• Identity: 297/1132 - (26%)
• Similarity: 471/1132 - (41%)
• Gaps: 270/1132 - (23%)

  Fly     4 LKVAVRVRPFNSREIDMDAQLIM-EMENKKTRLLKPR------LQSIRDAGRDNHHDFTFDYSYW 61
            |.||:|:||.:..|::..|.:|. :::::...||.|.      |::.|...:....|..||||
Zfish    12 LTVALRIRPLSDAELEEGATIIAHKVDDQMVVLLDPMEDPDDILRAHRSREKTYMFDVAFDYS-- 74

  Fly    62 SFDAEDPHFATQEQVYSDLGNDVVDCAYEGYNACVFAYGQTGSGKTFTMMGTPNNPGLIPRICEE 126
                     |||::||......:::....||||.|||||.||.|||:||:||...||:..|...:
Zfish    75 ---------ATQDEVYRYTTKGLIEGLISGYNATVFAYGPTGCGKTYTMLGTDREPGIYVRTLND 130

  Fly   127 LFARMRVGQESGTGYRTHASYLEIYNERVKDLLAAQSTGHGLRVREHRSLGPYVENLSQHAVSDF 191
            ||..:....:. ..|....||||||||.::||| ..|:|. |.:||.......|..:::.:..:.
Zfish   131 LFKAIEETSDD-MQYSVSMSYLEIYNEMIRDLL-NPSSGF-LDLREDSKGEIQVAGITEVSTINA 192

  Fly   192 DEIQECIARGNAQRTTASTNMNDTSSRSHAIFTITFVQAVFMNDMPSET-VSKIHLVDLAGSERA 255
            .||.|.:.:||.|||...|..|.|||||||:..:...|.....|:..|. .:::.::||||||||
Zfish   193 REIMELLMKGNKQRTQEPTAANQTSSRSHAVLQVVVRQQSRCRDILQEVRFARLFMIDLAGSERA 257

  Fly   256 NATGATGQRLKEGAHINKSLVTLGSVISALAEQTGGGHNSSSSALATTPNGASKRVLYIPYRDSI 320
            :.|...|||||||||||:||:.||:.|:||:|:.|.                    .|:.||||.
Zfish   258 SQTQNRGQRLKEGAHINRSLLALGNCINALSEKNGN--------------------KYVNYRDSK 302

  Fly   321 LTWLLKDSLGGNSKTIMIAALSPADCNYSETLSTLRYANRAKNI---INKPTVNEDTNV----KL 378
            ||.||||||||||:|:|||.:|||...:.::.:||.||:|||:|   :.:..:|...::    .:
Zfish   303 LTRLLKDSLGGNSRTVMIAHISPASLAFEDSRNTLTYADRAKSIRTRVKRNLLNVSYHIAQYTSI 367

  Fly   379 IRELREEINKLKSMLAG-----------DIHSLQPSLKVLADLQKKEAQEKVLTEEWTEKWKVAQ 432
            |.:||.||.:||..:|.           ||..:|..::..:. |:..|:...|.|:..:.::...
Zfish   368 ISDLRSEIQRLKKKIADQASRQINPDRTDIRHVQAEVQAHSS-QQSRAEMDQLREQLIDAFRQQM 431

  Fly   433 SILQEQKSLGLRKSGVGVVLDSEMPHLIGIHNDVTTGVTLYSLKEGETRIGS-------EDADVA 490
            .|  .::.:.|..|.:.:.:|:. .||:.|.:............:||.|..|       :|:|..
Zfish   432 DI--RKRLMELDNSNMEIQIDTS-KHLLTIADWEQERFRRRKKWQGERRKESFNKDESEKDSDSP 493

  Fly   491 QDIELAGDGIRAQHCSIFLKGGVVTLHPWPLAQCWVNAHLIDEPKQISQGDIILLGRTNIFRFNN 555
            :.:.   |....|..:| .:..:||              |:.|.|:|.:....|..|
Zfish   494 ESLP---DSTETQEVAI-ARENLVT--------------LMAEQKKIQKQKAGLEQR-------- 532

  Fly   556 PAEAAKLRKDLSRSQLDMSRLSLITSSKENL-LTCSIYSDEDGASPYKRPERQYYPQRPMSRDDP 619
               .|:||:...|.:..:.|.......:|.| |.|.::
Zfish   533 ---LAELREKARRLEELLPRRVSSEEQREVLCLLCKVH--------------------------- 567

  Fly   620 ELQDENRKILDTI---ENALKQLNVERVQMHDQYKTKVRKLTEELIRLEQEEMDGLQLL---NCR 678
            ||:.||.::..:.   :|.::|.||. ||..:|:    |.|..|:|:.:::.:|...||   :.:
Zfish   568 ELEIENAEMQSSALLKDNVIRQKNVV-VQRFEQH----RHLCHEIIQQQRQFIDDHSLLVPPHLQ 627

  Fly   679 EQELIARKDMLLWEKNNEK-VQID-------IVCRQISAFQTQLDSKKRDFSEYVAKELQEL-QD 734
            |...:..|:|  .|||.:: |.:|       .|..:.|..:..|.|:.||       .|||| .|
Zfish   628 ELYEMYMKEM--DEKNLDRVVALDKFTIRTLKVHHEGSLPKITLPSRGRD-------PLQELDSD 683

  Fly   735 CGKLDEMGMKIEEG-TPLNDELL---LQVSDSLDLFAAQF--IKDTV----------RRNNEEIR 783
            ...:..:.....:| |.|....|   |...|...:|.:..  :|:||          .:.|.|:
Zfish   684 QESVRTLASDNRQGRTKLRRHTLPPILPEPDGERVFKSSHKQMKNTVVMTPPPIHINGQGNREL- 747

  Fly   784 KLDEQIAEKERILNASTTKIAKVDETMLEIQAQLERLRLERAESEAESQAMRAKKQNMKLQLGNK 848
             |...:.|..|..:.|.:..:.:|.:              ...||..:.|....|:..::..|.:
Zfish   748 -LPSVLDEALRCSHLSHSMSSHLDSS--------------PESSENGTDAPLTPKERQQILRGVQ 797

  Fly   849 SMSTSTSTN-----EADDVSKSDTYETCDTFHTAQSNLSLVSS----PTITEGQQ-SP------- 896
            :::...:..     |.|.:.........|. ...:|||||..:    |.:..|:| ||
Zfish   798 NIAVKAARRRSKVLEIDALRLPPPPSPLDP-KKHKSNLSLSEAPPKGPVLRRGRQPSPELRHATS 861

  Fly   897 ---LSNCSCDA----------------------EDEAEDTRKDDLSGSSEETSRTCTAG------ 930
               ||:.:.|.                      |.:.|..|:...|.|.|.|.:..:..
Zfish   862 DDNLSSSTGDGPAPNGTWTRPRNRQAVRNAGPREQDFEGRRRKRRSRSFEVTGQALSQAKNTNQR 926

  Fly   931 --PSSGSGSGSVGIGGSGSAPSCTPSSQAIMSDSGVCLDSRNQAILQNGH-LNNYKQAVRTSDED 992
              |...:....:.|.|...||...|..:|             ||.|.... .:|..|
Zfish   927 FRPLDSTSDPHLHINGHPPAPLLRPQHRA-------------QAQLTKARPSHNIHQ-------- 970

  Fly   993 TGSCSSCELGRHSDVARPYCPLHSLRR 1019
            |||.        :||.....|.|.::|
Zfish   971 TGST--------ADVTSSNPPSHLIKR 989

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp98A	NP_524532.2	KISc_KIF1A_KIF1B	2..371	CDD:276816	146/377 (39%)
		Kinesin_assoc	370..478	CDD:465047	23/122 (19%)
		FHA_KIF16	449..556	CDD:438760	21/113 (19%)
		SMC_N	624..>864	CDD:481474	59/275 (21%)
		PX_KIF16B_SNX23	1131..1259	CDD:132784
kif19	XP_005156460.1	KISc_KIP3_like	11..346	CDD:276821	145/367 (40%)
		EnvC	340..>558	CDD:443969	50/250 (20%)