Protein Alignment Klp98A and sub

DIOPT Version :9

• Sequence 1: NP_524532.2
• Gene: Klp98A / 43310
• FlyBaseID: FBgn0004387
• Length: 1265
• Species: Drosophila melanogaster
• Sequence 2: NP_001286548.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Alignment Length: 631
• Identity: 154/631 - (24%)
• Similarity: 221/631 - (35%)
• Gaps: 225/631 - (35%)

  Fly    30 NKKTRLLKPRLQSIRDAGRDNHHDFTFDYSYWSFD-----------AEDPHFATQEQVY------ 77
            |||.||. ..:|...:.....:.|...:|.|.|.:           |:..:..|..||:
  Fly    34 NKKMRLF-DNIQESEEESFSEYSDTESEYKYQSSEATEGASCATSAADSSNVETGPQVFLRLRPV 97

  Fly    78 ---------SDLGNDVV-DCAYEG---------------------------YNACV--------- 96
                     |:..|.:: .|..:.                           |:.||
  Fly    98 KDASKAYIVSEEANVLITSCKVDSTSNNVNRMEKHFGFTSIFDSTVGQRDIYDTCVGPKIMEEEC 162

  Fly    97 ---FAYGQTGSGKTFTMMGTPNNPGLIPRICEELFA----------------------------- 129
               ..||.:|||||:|::|.....|:|||..|.:|.
  Fly   163 VTIMTYGTSGSGKTYTLLGDDVRAGIIPRALENIFTIYQDTVFRSPKLKLINGSIVFLQDDASLK 227

  Fly   130 --------------------RMRVGQESGTGYRTHA----------SYLEIYNERVKDLLAAQST 164
                                |::...:....:.|.|          |::|||||.|.||||....
  Fly   228 ELQIRKKLLDLCPDISAHHQRLKQVIDGDHMFETKASTDVSVLVWVSFVEIYNELVYDLLAIPPK 292

  Fly   165 GHGLRVREHRSL-------GPYVENLSQHAVSDFDEIQECIARGNAQRTTASTNMNDTSSRSHAI 222
            ...|.....::|       ..:::.|:...|:..:|....:..|..:.|.|||::|..|||||.:
  Fly   293 QDKLGEVPRKNLKIVGNKGHVFIKGLTSVFVTSSEEALRLLRLGQQRSTYASTSVNANSSRSHCV 357

  Fly   223 FTITFVQAVFMNDMPSETVSKIHLVDLAGSERANATGATGQRLKEGAHINKSLVTLGSVISALAE 287
            ||:..::   .|.....|.|.....|||||||.|.||.:|.||||..:||.||:.||..:.|
  Fly   358 FTVDILK---YNRSGITTQSSYKFCDLAGSERVNNTGTSGLRLKEAKNINTSLMVLGRCLDA--- 416

  Fly   288 QTGGGHNSSSSALATTPNGASKRVLYIPYRDSILTWLLKDSLGGNSKTIMIAALSPADCNYSETL 352
                         |:|.. ..|....||||||.||.||:.:|.|..|..||..::|.|..|.|.|
  Fly   417 -------------ASTVQ-KKKNADIIPYRDSKLTMLLQAALLGKEKLAMIVTVTPLDKYYEENL 467

  Fly   353 STLRYANRAKNIINK-PTVN---------------------------EDTNVKLIRELREEINKL 389
            :.|.:|:.|||||.| |.:.                           ||.||:    |:.||.:|
  Fly   468 NVLNFASIAKNIIFKEPVIKQHRVSYCGFMEFSKMSTCEGGDYTKELEDENVR----LQLEIEQL 528

  Fly   390 KSMLAGDIHSLQPSLKVLADLQKKEAQEKVLTEEWTEKWKVAQSILQEQKSLGLRKSGVGVVLDS 454
            |.     .|.||..|     |::|..:|...|         .|.|:|..|..
  Fly   529 KY-----DHVLQMQL-----LEEKLRRELTAT---------YQEIIQNNKKQ------------- 561

  Fly   455 EMPHLIGIHNDVTTGVTLYSLKEGETRIGSEDADVAQDIELAGDGI 500
                    :.|......|.:.:|.|..:.|:.....:.||...|.|
  Fly   562 --------YEDECEKKLLIAQRESEFMLSSQRRRYEEQIEDLKDEI 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp98A	NP_524532.2	KISc_KIF1A_KIF1B	2..371	CDD:276816	124/473 (26%)
		KISc	3..371	CDD:214526	124/473 (26%)
		Kinesin_assoc	370..478	CDD:292801	23/134 (17%)
		FHA	456..555	CDD:238017	9/45 (20%)
		PX_KIF16B_SNX23	1131..1259	CDD:132784
sub	NP_001286548.1	KISc	89..477	CDD:276812	105/407 (26%)
		Kinesin	93..479	CDD:278646	105/405 (26%)
		GBP_C	<512..603	CDD:303769	30/132 (23%)
		coiled coil	576..586	CDD:293879	3/9 (33%)
		coiled coil	592..603	CDD:293879	4/8 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437721
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030