DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Klp98A and ncd

DIOPT Version :9

Sequence 1:	NP_524532.2	Gene:	Klp98A / 43310	FlyBaseID:	FBgn0004387	Length:	1265	Species:	Drosophila melanogaster
Sequence 2:	NP_001287592.1	Gene:	ncd / 43517	FlyBaseID:	FBgn0002924	Length:	700	Species:	Drosophila melanogaster

Alignment Length:	393	Identity:	127/393 - (32%)
Similarity:	196/393 - (49%)	Gaps:	71/393 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SLKVAVRVRPFNSREIDMDAQLIMEMENKKTRLL---------KPRLQSIRDAGRDNHHDFTFDY 58
            :::|..|:||              .:|:::.|:.         ...||||     |.........
  Fly   348 NIRVFCRIRP--------------PLESEENRMCCTWTYHDESTVELQSI-----DAQAKSKMGQ 393

  Fly    59 SYWSFDAEDPHFATQEQVYSDLGNDVVDCAYEGYNACVFAYGQTGSGKTFTMMGTPNNPGLIPRI 123
            ..:|||......::|..:: ::.:.::..|.:|||.|:|||||||||||:||.|.|.:.|:|||.
  Fly   394 QIFSFDQVFHPLSSQSDIF-EMVSPLIQSALDGYNICIFAYGQTGSGKTYTMDGVPESVGVIPRT 457

  Fly   124 CEELFARMRVGQESGTGYRTHASYLEIYNERVKDLLAAQSTGHGLRVREHRSLGPYVENLSQHAV 188
            .:.||..:|..:..|..|...|::||||||.:.|||:.:.....:|:.::.....||.|:::..|
  Fly   458 VDLLFDSIRGYRNLGWEYEIKATFLEIYNEVLYDLLSNEQKDMEIRMAKNNKNDIYVSNITEETV 522

  Fly   189 SDFDEIQECIARGNAQRTTASTNMNDTSSRSHAIFTITFVQAVFMNDMPSE-TVSKIHLVDLAGS 252
            .|.:.::..:......|.||||..|:.||||||   :|.::.:..:....| :|..|:|||||||
  Fly   523 LDPNHLRHLMHTAKMNRATASTAGNERSSRSHA---VTKLELIGRHAEKQEISVGSINLVDLAGS 584

  Fly   253 ERANATGATGQRLKEGAHINKSLVTLGSVISALAEQTGGGHNSSSSALATTPNGASKRVLYIPYR 317
            |    :..|..|:.|..:||:||..|.:||.||.::..                      :||||
  Fly   585 E----SPKTSTRMTETKNINRSLSELTNVILALLQKQD----------------------HIPYR 623

  Fly   318 DSILTWLLKDSLGGNSKTIMIAALSP-ADCNYSETLSTLRYA--------NRAK--NIINKPTVN 371
            :|.||.||..||||||||:|...:|| .|| :.|::.:||:|        .:||  ..:|....|
  Fly   624 NSKLTHLLMPSLGGNSKTLMFINVSPFQDC-FQESVKSLRFAASVNSCKMTKAKRNRYLNNSVAN 687

  Fly   372 EDT 374
            ..|
  Fly   688 SST 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klp98A	NP_524532.2	KISc_KIF1A_KIF1B	2..371	CDD:276816	125/388 (32%)
		KISc	3..371	CDD:214526	125/388 (32%)
		Kinesin_assoc	370..478	CDD:292801	2/5 (40%)
		FHA	456..555	CDD:238017
		PX_KIF16B_SNX23	1131..1259	CDD:132784
ncd	NP_001287592.1	KISc_C_terminal	346..672	CDD:276817	122/373 (33%)
ncd	NP_001287592.1	KISc	348..678	CDD:214526	124/379 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437731
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930