Protein Alignment Klp98A and pav

DIOPT Version :9

• Sequence 1: NP_524532.2
• Gene: Klp98A / 43310
• FlyBaseID: FBgn0004387
• Length: 1265
• Species: Drosophila melanogaster
• Sequence 2: NP_477025.1
• Gene: pav / 38515
• FlyBaseID: FBgn0011692
• Length: 887
• Species: Drosophila melanogaster
• Alignment Length: 1087
• Identity: 235/1087 - (21%)
• Similarity: 395/1087 - (36%)
• Gaps: 382/1087 - (35%)

  Fly     4 LKVAVRVRPFNSREIDMDAQLI-MEMENKKTRLLKPRLQSIRDAGRDNHH----------DFTFD 57
            :.|..||||..|     ||.|. :.::|..|..|.|:.|.::      ||          .:.|.
  Fly    37 VNVFCRVRPLQS-----DADLTSLRVKNSTTIALNPQDQLLQ------HHKPHNGAQREVQYIFK 90

  Fly    58 YSYWSFDAEDPHFATQEQVYSDLGNDVVDCAYEGYNACVFAYGQTGSGKTFTMMGTPNNPGLIPR 122
            :.:      .|. |||:.||:.:...:|:...:|.|:.:|.||.||||||:||.|...:.|::||
  Fly    91 HVF------QPD-ATQQDVYAAVAQPLVENLLKGRNSLLFTYGVTGSGKTYTMTGNLRHRGIMPR 148

  Fly   123 ICEELFARMR------------------------------------------------------- 132
            ..:.||..:.
  Fly   149 CLDVLFRTISDYQAKKFVFKPDKLNGFEILSEEDALLERQHEMNQRFAGSGRFAFRHKDSDPEIA 213

  Fly   133 ----------VGQESGTGYRTHASYLEIYNERVKDLL---AAQSTGHGLRVREHRSLGPYVENLS 184
                      :|.:....|....:|:||||..|.|||   ..|.|.....:||..:...:|..::
  Fly   214 SQASVEPIPLLGLDEDNMYSVFVTYIEIYNNSVYDLLEDSGIQKTLQSKIIREDANRHMFVHGVT 278

  Fly   185 QHAVSDFDEIQECIARGNAQRTTASTNMNDTSSRSHAIFTITFVQAV-------FMNDMPSETVS 242
            :..|...::..|....|..::....|.:|..|||||::|.|..|||.       .:.|..:.|||
  Fly   279 EVEVKTVEDALEVFQMGQKRKRMGHTVLNAESSRSHSVFNIRLVQAPTDSQGENVVQDRQNITVS 343

  Fly   243 KIHLVDLAGSERANATGATGQRLKEGAHINKSLVTLGSVISALAEQTGGGHNSSSSALATTPNGA 307
            ::.|||||||||::.|..||.||:|..:||.||:||.:.:..|.|          :.||.:...|
  Fly   344 QLSLVDLAGSERSSRTKNTGVRLREAGNINNSLMTLRTCLEYLRE----------NQLAASNGLA 398

  Fly   308 SKRVLYIPYRDSILTWLLKDSLGGNSKTIMIAALSPADCNYSETLSTLRYANRAKNI-INKPT-V 370
            .|:|   |||||.:|.:.|:...|..:..||..::|...:|.|.:..:::|...:.: |.:.| :
  Fly   399 PKKV---PYRDSKITHMFKNYFDGEGQVSMIVCINPRIEDYDENMQVMKFAEMTQEVQIARATPM 460

  Fly   371 NEDTNVKLIRELREEINKLKSMLAGDIHSLQPSLKVLADLQKKEAQEKVLTEEWTEKWKVAQSIL 435
            .:|..   :...|.:.|||                                      :|:|.:.|
  Fly   461 KQDLG---LTPGRRKANKL--------------------------------------FKIAVNNL 484

  Fly   436 QEQKSLGLRKSGVGVVLDSEMPHLIGIHNDVTTGVTLYSLKEGETRIGSEDADVAQDIELAGDGI 500
            .|   ||:.:                                            |:|:|:.
  Fly   485 NE---LGIPE--------------------------------------------AKDLEVD---- 498

  Fly   501 RAQHCSIFLKGGVVTLHP-WPLAQCWVNAHLIDEPK-QISQGDIILLGRTNIFRFNNPAEAAKLR 563
                     .|.|.:|.| :|       |:.:|.|: ||...:::          :...:..:.|
  Fly   499 ---------VGLVYSLGPDFP-------AYEMDSPEAQIKIRELM----------HYLEQRIEKR 537

  Fly   564 KDLSRSQLDMSRLSLITSSKENLLTCSIYSDEDGASPYKRPERQYYPQRPMSRDDPELQDENRKI 628
            |.| |:.||              :.|                                 |..|::
  Fly   538 KKL-RANLD--------------IKC---------------------------------DSFRQM 554

  Fly   629 LDTIENALKQLNVERVQMHDQYKTKVRK--LTEELIRLEQEEMDGL-QLLNCREQEL------IA 684
            |..::....||..|...:...||.:..:  ..|:.:|:.:..:|.| ..|:.:|:::      :.
  Fly   555 LMNLDRDNLQLRTELASLKAVYKQERDRSAALEKKVRIHESSIDVLNNTLSKQERQIEELTFKLN 619

  Fly   685 RKDMLLWEKNNEKVQIDIVCRQISAFQTQL----DSKKRDFSEYVAKELQELQDCGKLDEMGMKI 745
            .|:.:|.:|.:||.      :|...|.::|    |..||:|         ||    ||.|..:|:
  Fly   620 EKENMLTQKEHEKE------KQKKKFSSKLAVESDKNKREF---------EL----KLREQRVKL 665

  Fly   746 EEGTPLNDELLLQVSDSLDLFAAQFIKDTVRRNNEEIRKL------DEQIAEKERILNASTTKIA 804
            :|...:.||.|..||:.|              .:|::..|      :..:.||:|....:.|:.:
  Fly   666 QERMRIKDEKLRLVSNIL--------------QSEDLPSLPRSQSSENILNEKDRGAYTARTEES 716

  Fly   805 KVDETMLEI--------QAQLERLRLERAESE--AESQAMRAKKQNMKLQLGNKSMSTSTSTNEA 859
            .|..|..:|        .|...|.|..|:..:  .|.:|.........:|...|:..:.|...:.
  Fly   717 SVPATRTDIYATPRHGAAAANNRHRRSRSAGDKWLEHRAANPVPLGTIMQPYLKNRKSVTKLTDL 781

  Fly   860 DDVSKSDTYETC------DTFHTAQSNL---SLVSSPTITEGQQSPLSNCSCDAEDEA--EDTRK 913
            .:::...|.:.|      ||....::.|   :::  ||...|.|...::..|..:...  ..|||
  Fly   782 KELTAHGTTKYCLVSQDADTDGDVETKLYKGNVI--PTCGGGAQVVFNDVECLKQKSPVHSPTRK 844

  Fly   914 DDLSGSSEETSRTCTAGPSSGSGSGSVGIGGSGSAPSCTPSSQAIMS 960
                            .||:|:.|   .:|| |:.||...|:|.:.|
  Fly   845 ----------------RPSNGNIS---ALGG-GAVPSTVTSAQDVAS 871

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp98A	NP_524532.2	KISc_KIF1A_KIF1B	2..371	CDD:276816	122/454 (27%)
		KISc	3..371	CDD:214526	122/454 (27%)
		Kinesin_assoc	370..478	CDD:292801	11/107 (10%)
		FHA	456..555	CDD:238017	13/100 (13%)
		PX_KIF16B_SNX23	1131..1259	CDD:132784
pav	NP_477025.1	KISc_KIF23_like	35..450	CDD:276819	120/443 (27%)
		Kinesin	42..452	CDD:278646	119/440 (27%)
		MKLP1_Arf_bdg	735..837	CDD:293148	19/103 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437730
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030