Protein Alignment Klp98A and klp5

DIOPT Version :10

• Sequence 1: NP_524532.2
• Gene: Klp98A / 43310
• FlyBaseID: FBgn0004387
• Length: 1265
• Species: Drosophila melanogaster
• Sequence 2: NP_595703.1
• Gene: klp5 / 2540361
• PomBaseID: SPBC2F12.13
• Length: 883
• Species: Schizosaccharomyces pombe
• Alignment Length: 1009
• Identity: 254/1009 - (25%)
• Similarity: 401/1009 - (39%)
• Gaps: 313/1009 - (31%)

  Fly     2 SSLKVAVRVRPFNSREIDMDAQLIMEME------------------------------------- 29
            ||:.|.||||||::.|   .|.||...:
pombe     5 SSITVTVRVRPFSTAE---SANLIASSDRLSFGTSSSLRNPGSGRQIRRVVKVLDGRVLVFDPPD 66

  Fly    30 ------NKKTRLLKPRLQSIRDAGR--DNHHDFTFDYSYWSFDAEDPHFATQEQVYSDLGNDVVD 86
                  :...|.|....||:....|  :|...|..|..| :||......|||:|||......::|
pombe    67 ETTATLSATNRRLSTSQQSLARLSRKSNNSAGFGRDLRY-AFDRVFDETATQQQVYERTARPLLD 130

  Fly    87 CAYEGYNACVFAYGQTGSGKTFTMMGTPNNPGLIPRICEELFARMRVGQESGTGYRTHASYLEIY 151
            ...:|:||.:||||.||.|||.|:.||..:||||....:|||.||...::... :....||||||
pombe   131 NILDGFNATIFAYGATGCGKTHTISGTMQDPGLIYLTLKELFERMDHLRDEKI-FDLRLSYLEIY 194

  Fly   152 NERVKDLLAAQSTGHG--LRVREHRSLGPYVENLSQHAVSDFDEIQECIARGNAQRTTASTNMND 214
            ||.::|||.:.:....  |.:||.......|..|:..:....:||.:.|.:|||.||.:.|..|.
pombe   195 NETIRDLLVSPTPNQAKPLNLREDADRRITVPGLTSLSPESLEEIIDIIMKGNANRTMSPTEANA 259

  Fly   215 TSSRSHAIFTITFVQ---AVFMNDMPSETVSKIHLVDLAGSERANATGATGQRLKEGAHINKSLV 276
            .||||||:..:|.:|   ...:|:  ..|::.:.::||||||||.||...|.||.|||:|||||:
pombe   260 ASSRSHAVLQVTLIQKPRTAGINE--DHTLATLSIIDLAGSERATATKLRGSRLFEGANINKSLL 322

  Fly   277 TLGSVISALAEQTGGGHNSSSSALATTPNGASKRVLYIPYRDSILTWLLKDSLGGNSKTIMIAAL 341
            .||:.|:||.:                |:    |..::|||||.||.|||.|||||.:|:||..:
pombe   323 ALGNCINALCD----------------PH----RRAHVPYRDSKLTRLLKFSLGGNCRTVMIVCV 367

  Fly   342 SPADCNYSETLSTLRYANRAKNI---INKPTVNEDTN----VKLIRELREEINKLKSMLAG-DIH 398
            ||:..:|.||.:||:||||||||   :.:..::.|.:    ||.|.||||:|::|::.||. |:.
pombe   368 SPSSVHYEETHNTLKYANRAKNIKTEVLRNMISVDRHVSQYVKAIVELREQISELENRLAQIDLS 432

  Fly   399 SLQPSLKVLADLQKKEAQEKVLTEEWTEKWKVAQS------------------------------ 433
            |           |...:.:..:|:.:..:.|:|::
pombe   433 S-----------QSNGSDQDAVTQSFAHESKLAEARNLLRMTFEETLPLQNDTINKVEKVKHFDD 486

  Fly   434 --------------------------ILQEQKSLGLRKSGVGVVLDSEM---------PHLIGIH 463
                                      :..:.:||..|::.:...:|.|:         .|:|..:
pombe   487 SIRVLKYWLSCYERILPNSADERVFLVRSKLESLLTRRAEIIADIDPELVYQKFQRSVSHIINTY 551

  Fly   464 NDVTTGVTLYSLKEGETRIGSEDADVAQD-IELAGDGIRAQ------------------------ 503
            ..  .|.|:|             |||.|| ::|....|..|
pombe   552 KQ--EGATMY-------------ADVLQDEVDLLKSIIENQVLDAQNKVDEFTPVLESLLRSSFK 601

  Fly   504 HCSIFLKGGVVTLHPWPLAQCWVNAHLIDEPKQISQGDIILLGRTNIFRFNNPAEAAK-LRKDLS 567
            ..|:..:||:..|  :.:.:.|:....:.|...||    :|   :..::.|:.::.:: :.:|..
pombe   602 ASSLLKEGGMQEL--FSILEKWLLGIGLGEKPNIS----VL---SESYKLNSTSDDSRTINRDRV 657

  Fly   568 RS-------QLDMSRLSLITSSKENLLTC------------SIYSDEDGASPYKRP--------- 604
            .|       ..::.|:..:.|.|:.::..            |:.:.:.|||.|..|
pombe   658 HSFPTQPLLNNNLPRMFFVKSPKKPVVFSKRSPKKRVRFDDSMSTSDSGASAYNSPIQTSKLKNM 722

  Fly   605 ---ERQYYPQRPMSRDDPELQDENRKILDTIENALKQLNVERVQMHDQYKTKVRKLTEELIRLEQ 666
               ...:.|..|..:     :.||:..:|...|....::.                     .||.
pombe   723 NFFNTMHMPSTPAHK-----RPENKNQIDVEINLTSPVSP---------------------MLED 761

  Fly   667 EEMDGLQLLNCREQELIARKDMLLWEKNNEKVQIDIVCRQISAFQTQLDSKKRDFSEYVAKELQE 731
            :...||.:.:..|::         .|.|:|..|:|.:..:        ||...|.|
pombe   762 KPEPGLLIKSPLEKK---------QEVNSESTQLDQLLAE--------DSSTDDVS--------- 800

  Fly   732 LQDCGKLDEMGMKIEEGTPLNDELLLQVSDSLDLFAAQFIKDTVRRNNEEIRKLDEQIAEKERIL 796
               ...||.:.:   :|:|:.     :|.| |:...|.....|...|||.|...|....:..:.|
pombe   801 ---LPHLDTIDL---DGSPVP-----KVPD-LNFSRANMDSPTFILNNEAIHNFDFSKPKTRQSL 853

  Fly   797 NASTTKIAKVDETMLEIQAQLERLRLERAESEAE 830
            ::.||       ..|...|.:.|..|..||:|.|
pombe   854 SSLTT-------LHLSNPANIIRKSLSMAENEEE 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp98A	NP_524532.2	KISc_KIF1A_KIF1B	2..371	CDD:276816	152/421 (36%)
		Kinesin_assoc	370..478	CDD:465047	28/177 (16%)
		FHA_KIF16	449..556	CDD:438760	25/140 (18%)
		SMC_N	624..>864	CDD:481474	43/207 (21%)
		PX_KIF16B_SNX23	1131..1259	CDD:132784
klp5	NP_595703.1	KISc_KIP3_like	6..390	CDD:276821	149/410 (36%)