Protein Alignment Klp98A and kif28

DIOPT Version :10

• Sequence 1: NP_524532.2
• Gene: Klp98A / 43310
• FlyBaseID: FBgn0004387
• Length: 1265
• Species: Drosophila melanogaster
• Sequence 2: XP_031758561.1
• Gene: kif28 / 101732886
• XenbaseID: XB-GENE-22065598
• Length: 913
• Species: Xenopus tropicalis
• Alignment Length: 846
• Identity: 277/846 - (32%)
• Similarity: 417/846 - (49%)
• Gaps: 150/846 - (17%)

  Fly     3 SLKVAVRVRPFNSREIDMDAQLIMEMENKKTRLLKPRLQSIRDAGRDNHHDFTFDYSYWSF---- 63
            |:|||||||||:.||.|..::.::.|:...|.:..|     ::.|  |...|.||.:|||.
 Frog    43 SVKVAVRVRPFSKREKDASSKCVISMKTNCTTICDP-----KNVG--NEKTFKFDLAYWSHSEYL 100

  Fly    64 ---------DAEDPHFATQEQVYSDLGNDVVDCAYEGYNACVFAYGQTGSGKTFTMMGTPNNPGL 119
                     |.....:|.|:.|:.|||..::|.|::||||.:.|||||||||:::|:|...|.|:
 Frog   101 KNTESTLVPDGSYSRYADQKTVFQDLGQGILDNAWQGYNATLLAYGQTGSGKSYSMIGYGTNRGI 165

  Fly   120 IPRICEELFARMRVGQESGTGYRTHASYLEIYNERVKDLLAAQSTGHGLRVREHRSLGPYVENLS 184
            ||.:|||||..:...||....|:...|.||||||:|.|||:......||:|||.:..|.||:.|.
 Frog   166 IPLVCEELFRAIENNQEKNKQYQVTFSMLEIYNEQVTDLLSKTKKSGGLKVREDQHQGFYVDGLK 230

  Fly   185 QHAVSDFDEIQECIARGNAQRTTASTNMNDTSSRSHAIFTITFVQAVFMNDMPSETVSKIHLVDL 249
            ......:.:|:..|.:|...||||||:||.:|||||.:.||.|.|.:...|:..:  |.|:||||
 Frog   231 LVPCESYAQIERLIEQGKKIRTTASTSMNASSSRSHMVITIQFKQILLKEDITKQ--SSINLVDL 293

  Fly   250 AGSERANATGATGQRLKEGAHINKSLVTLGSVISALAEQTGGGHNSSSSALATTPNGASKRVLYI 314
            |||||..::.:.|.||:||..:|.||.|||:|||||||...|                 |:||:|
 Frog   294 AGSERQKSSASEGDRLREGTCVNLSLTTLGNVISALAEAAMG-----------------KKVLHI 341

  Fly   315 PYRDSILTWLLKDSLGGNSKTIMIAALSPADCNYSETLSTLRYANRAKNIINKPTVNEDTNVKLI 379
            |||||:||.||:.:|||||:|:||||:||||..|.|||||||||.|||.|.||..:|.....:||
 Frog   342 PYRDSVLTKLLQSALGGNSRTVMIAAISPADICYEETLSTLRYAERAKKIKNKAIINAGPTERLI 406

  Fly   380 RELREEINKLKSMLAGDIHS--------------LQPSLKVLADLQKKEAQEKVLTEEWTEKWKV 430
            :||:.|.|||.|.|||..:|              :| ::::..:.|.:||:     :||.:::
 Frog   407 KELKAENNKLLSRLAGLGNSGKRQLSGCYENELRIQ-TMQITWEHQLQEAR-----KEWEQQY-- 463

  Fly   431 AQSILQEQKSLGLRKSGVGVVLDSEMPHLIGIHND-VTTGVTLYSLKEGETRIGSEDADVAQDIE 494
             .:|.||::.:.|            .|:|:.|:.| ..:||..:.::||.:.:|.:.::|   |.
 Frog   464 -AAITQERRMMQL------------YPYLLNINEDPQLSGVLKHFIQEGASDVGQDPSNV---IT 512

  Fly   495 LAGDGIRAQHCSIFLKGGVVTLHPWPLAQCWVNAHLIDEPKQISQGDIILLGRTNIFRF-NNPAE 558
            |.|.||..||.:.......|.:.|....:..||...|....::...|.|:||..:.:.: ..|||
 Frog   513 LRGLGILPQHATFINSESKVFVKPHGKGKVIVNGVPIVLNTKLQHLDRIILGSNSAYLYIGFPAE 577

  Fly   559 AAKLRKDLSRSQLDMSRLSLITSSKENLLTCSIYSDEDGASPYKRPE-------RQYYPQRPMSR 616
            ...  .||.|...|..:..|..:...::.|.....:::|     :|:       ..:....|:..
 Frog   578 RGP--DDLCRFDYDFFQSELAAAEGFSVDTLGPVHNKEG-----KPDPSVLAVFHDFIKLMPLVA 635

  Fly   617 DDPELQDENRKILDTIENALKQLNVERVQMHDQYKTKVRKLTEELIRLEQEEMDGLQLLNCREQE 681
            :..::.:|..|.| ..|..:|.|.:...:.:|..|    :::.::|.         |:.|
 Frog   636 EANQMSEELSKDL-KFELKVKNLALTDSRGYDLQK----EISVKVIN---------QITN----- 681

  Fly   682 LIARKDMLLWEK----NNEKVQIDIVCRQISAFQTQLDSKKRDFSEYVAK--------ELQELQD 734
                 .:.:|.|    |.:.:..::..|.:......||.:...|.:.|..        .||.|..
 Frog   682 -----QVWIWSKSKFINRKFLMEELYQRYLDGGDISLDRESDPFWDPVEVIHLGSAHIWLQSLAY 741

  Fly   735 CGKLDEMGMKIEEGTP-LNDELLLQVSDSLDLFAAQFIKDTVRRNNEEI----------RKLDEQ 788
            |       ||:||.|. ||.|   .|.:::.:.......||.|...||.          ||::.|
 Frog   742 C-------MKLEEQTELLNSE---GVEEAILVINITPCSDTERPFGEEDIVIDPLELLGRKIEFQ 796

  Fly   789 I 789
            |
 Frog   797 I 797

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp98A	NP_524532.2	KISc_KIF1A_KIF1B	2..371	CDD:276816	174/380 (46%)
		Kinesin_assoc	370..478	CDD:465047	30/122 (25%)
		FHA_KIF16	449..556	CDD:438760	26/108 (24%)
		SMC_N	624..>864	CDD:481474	41/189 (22%)
		PX_KIF16B_SNX23	1131..1259	CDD:132784
kif28	XP_031758561.1	Motor_domain	42..398	CDD:473979	174/380 (46%)
		FHA_KIF28P	477..574	CDD:438761	26/99 (26%)
		KIF1B	691..725	CDD:463574	5/33 (15%)