Protein Alignment Klp98A and kif28

DIOPT Version :9

• Sequence 1: NP_524532.2
• Gene: Klp98A / 43310
• FlyBaseID: FBgn0004387
• Length: 1265
• Species: Drosophila melanogaster
• Sequence 2: XP_021322979.1
• Gene: kif28 / 100537112
• ZFINID: ZDB-GENE-130530-1027
• Length: 1037
• Species: Danio rerio
• Alignment Length: 1166
• Identity: 325/1166 - (27%)
• Similarity: 505/1166 - (43%)
• Gaps: 275/1166 - (23%)

  Fly     4 LKVAVRVRPFNSREIDMDAQLIMEMENKKTRLLKPRLQSIRDAGRDNHHDFTFDYSYWS------ 62
            :||||||||||.||.|..::.|:.|.:....:..||       ...|...|||||:|||
Zfish    14 VKVAVRVRPFNKRERDAGSRCIISMTSNSISIQDPR-------NSQNSRTFTFDYTYWSHSGFSR 71

  Fly    63 -----FDAEDP--HFATQEQVYSDLGNDVVDCAYEGYNACVFAYGQTGSGKTFTMMGTPNNPGLI 120
                 |..|:.  .:|.|..|:.|||..::|.|.:||||.:.|||||||||:::|:|...|.|||
Zfish    72 NKDGLFVPEETGGRYADQASVFLDLGQGILDNALQGYNATLLAYGQTGSGKSYSMVGYGPNKGLI 136

  Fly   121 PRICEELFARMRVGQESGTGYRTHASYLEIYNERVKDLLAAQS-TGHGLRVREHRSLGPYVENLS 184
            |.:|:.||..:|..|:| ...:...|.||||||:|.|||:..| :..||||||.:..|.|||.|.
Zfish   137 PTLCQRLFQSIRSMQDS-RQCQVFFSMLEIYNEQVVDLLSKSSRSAGGLRVREDQQTGFYVEGLR 200

  Fly   185 QHAVSDFDEIQECIARGNAQRTTASTNMNDTSSRSHAIFTITFVQAVFMNDMPSETVSKIHLVDL 249
            :.......::::.:.:|...||||:|::|::|||||.:..:...| :|..:..::. |.|:||||
Zfish   201 RVPCDSALQVEQLMEQGTRTRTTAATHINNSSSRSHMLIIVQLKQ-IFSKECITKQ-SNIYLVDL 263

  Fly   250 AGSERANATGATGQRLKEGAHINKSLVTLGSVISALAEQTGGGHNSSSSALATTPNGASKRVLYI 314
            |||||..::|:.|.|||||..||.||.|||:||||||:...|                  :.:||
Zfish   264 AGSERQRSSGSEGDRLKEGTAINLSLTTLGNVISALADMALG------------------KKIYI 310

  Fly   315 PYRDSILTWLLKDSLGGNSKTIMIAALSPADCNYSETLSTLRYANRAKNIINKPTVNEDTNVKLI 379
            |||||:||.||:.:|||||:|:|||.|||||..|.|:|||||||.|||.|.||..|||....:|:
Zfish   311 PYRDSVLTKLLQSALGGNSRTVMIATLSPADICYEESLSTLRYAERAKKIQNKAVVNESPTERLV 375

  Fly   380 RELREEINKL---KSMLAGDIHSLQPSLKVLAD-LQKKEAQEKVLTEEWTE-------KWKVA-Q 432
            :||:.|..||   .|.|..:....:...|.|.. |...|.|.:.:...|.:       .|:.. .
Zfish   376 KELKAENAKLLLRLSRLGQEGRKAEDESKELRRLLTHNELQIRAIQTLWEQHLQEALKDWETQYA 440

  Fly   433 SILQEQKSLGLRKSGVGVVLDSEMPHLIGIHND--VTTGVTLYSLKEGETRIGSEDADVAQDIEL 495
            :|.||::.:.:            .|:::.::.|  :::.|.|: ::|||..||..| :..:.:.:
Zfish   441 TITQERRMMQM------------YPYIMNVNEDAQLSSVVKLF-IQEGEWDIGLAD-NSPRALSI 491

  Fly   496 AGDGIRAQHCSIFLKGGVVTLHPWPLAQCWVNAHLIDEPKQISQGDIILLGRTNIFRF-NNPAEA 559
            .|.||:.:|.....:...|::.|...|:..||...:.:..::...|.::||..:.:.| ..|:|
Zfish   492 RGLGIQEKHAVFSNQQRRVSITPVSGAKVIVNGLQVSKRTELQHLDRLVLGSNSTYLFIGFPSE- 555

  Fly   560 AKLRKDLSRSQLDMSRLSLITSSKENLLT-CSIYSDEDGASPYKRPE-------RQYYPQRPMSR 616
             :..:|.||...|..:..|..:...::.: |    |:.|..|: :|:       ..|....||..
Zfish   556 -RSAEDWSRYDYDYFQSELAAAEGFHIQSLC----DDQGHRPH-QPDPSLLAVFYDYIKLMPMVT 614

  Fly   617 DDPELQDENRKILDTIENALKQLNVERVQMHDQYKTKVRKLTEELIRLEQEEMDGLQLLNCREQE 681
            :..::..|.:|.:: .:..:|.|.:...:.||..|....|:|.
Zfish   615 EANQMSAELKKGVE-FKLEIKNLAMSDSKGHDLEKDIAVKVTS---------------------- 656

  Fly   682 LIARKDMLLWEKN---NEKVQIDIVCRQISAFQTQLD----SKKRDFSEYVAKELQELQDCGKLD 739
             :..|.:.:|.|.   |.|..::.|.:|..|.....|    .:.||
Zfish   657 -VESKQVWMWSKAKFINRKFLMEEVYQQQVAGGEGADRAPLPRDRD------------------- 701

  Fly   740 EMGMKIEEGTPLNDELLLQVSDSLDLFAAQ-FIKDTVRRNNEEIRKLDEQI------AEKERILN 797
                      |..|.|     :.|.|.:|. :::....|     ..|:||:      ..:|.||.
Zfish   702 ----------PFWDPL-----EPLHLGSAHLWLQSLAFR-----IPLEEQVEMVGPEGTEEAILQ 746

  Fly   798 A-----STTKIAKVDETMLEIQAQLERLRLE-----------RAESEAESQAMR----------- 835
            |     |...:|..::.:|...::|...||:           |...||.::.::
Zfish   747 AQLVPCSPAGLALGEDDILIDPSELLGKRLDFQLVLDQCCGLRWVKEARNRGVQIGFQVFDCPQP 811

  Fly   836 ----AKKQNMKLQLGNKSMSTSTSTNEADDVSKSDTYETCDTFHTAQSNLSLVSSPTITEGQQSP 896
                |...|:...|.::...|:..|::             |..:..|||..::....:.||....
Zfish   812 LYTPAVWHNVNPLLDHRVQFTALRTSQ-------------DLLNYLQSNALVLELWGLQEGCSEL 863

  Fly   897 LSNCSCDAEDEAEDTRKDDLSGSSEETSRTCTAGPSSGSGSGSVGIGGSGSAPSCTPSSQAI--M 959
            |||.......:.:....|.:|.|...|:.|                |.|..:.|.....|.:  :
Zfish   864 LSNMDGMKMTQEDSVIIDKISASEHLTAET----------------GSSDLSSSLRALHQDLDKL 912

  Fly   960 SDSGVCLDSRNQAILQNGHLNNYKQAV---RTSDEDTGSCSSCELGRHSDVARPYC--------- 1012
            .::...|...|.|:.:  .||:.:..|   |...|..||            .||.|
Zfish   913 RNANAALKKENSALRE--QLNSSRNGVENNRGRQERRGS------------LRPSCDAEFAKALK 963

  Fly  1013 -----------PLHSLRRKIAAQKALIMKNLETDLNKAQL--DEHIADLQDLQRRYIQMEQ 1060
                       .|..|||...::        |.||...:|  |||...|:|...   |:||
Zfish   964 VFYHSMTSVRGQLQRLRRHKPSE--------EEDLLGLRLFVDEHTFLLKDFSE---QLEQ 1013

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp98A	NP_524532.2	KISc_KIF1A_KIF1B	2..371	CDD:276816	171/380 (45%)
		KISc	3..371	CDD:214526	171/380 (45%)
		Kinesin_assoc	370..478	CDD:292801	25/121 (21%)
		FHA	456..555	CDD:238017	23/101 (23%)
		PX_KIF16B_SNX23	1131..1259	CDD:132784
kif28	XP_021322979.1	Motor_domain	14..367	CDD:328930	171/380 (45%)
		FHA	453..551	CDD:238017	23/99 (23%)
		KIF1B	670..708	CDD:315155	11/71 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123768at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920