Protein Alignment Klp98A and kif1a

DIOPT Version :9

• Sequence 1: NP_524532.2
• Gene: Klp98A / 43310
• FlyBaseID: FBgn0004387
• Length: 1265
• Species: Drosophila melanogaster
• Sequence 2: XP_031758411.1
• Gene: kif1a / 100127546
• XenbaseID: XB-GENE-960470
• Length: 1830
• Species: Xenopus tropicalis
• Alignment Length: 1556
• Identity: 430/1556 - (27%)
• Similarity: 666/1556 - (42%)
• Gaps: 444/1556 - (28%)

  Fly     2 SSLKVAVRVRPFNSREIDMDAQLIMEMENKKTRLLKPRLQSIRDAGRDNHHDFTFDYSYWSFDA- 65
            :|:||||||||||||||..|::.|::|....|.::.|:      ..::....|:|||||||..:
 Frog     4 ASVKVAVRVRPFNSREIGKDSKCIIQMSGNTTTIVNPK------QPKETPKSFSFDYSYWSHTSE 62

  Fly    66 EDPHFATQEQVYSDLGNDVVDCAYEGYNACVFAYGQTGSGKTFTMMG--TPNNPGLIPRICEELF 128
            ||..:|.|.|||.|:|.:::..|:||||.|:|||||||:||::||||  .|...|:||::||:||
 Frog    63 EDSQYAGQRQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPTQQGIIPQLCEDLF 127

  Fly   129 ARMRVGQESGTGYRTHASYLEIYNERVKDLLAAQSTGHGLRVREHRSLGPYVENLSQHAVSDFDE 193
            :|:.........|....||:|||.|||:|||..::.|: ||||||..||||||:||:.||:.:.:
 Frog   128 SRISDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGN-LRVREHPLLGPYVEDLSKLAVTSYQD 191

  Fly   194 IQECIARGNAQRTTASTNMNDTSSRSHAIFTITFVQAVFMNDMPSET----VSKIHLVDLAGSER 254
            ||:.:..||..||.|:||||:|||||||:|.|.|.|.  .:|..::|    ||||.|||||||||
 Frog   192 IQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQR--RHDADAQTTTEKVSKISLVDLAGSER 254

  Fly   255 ANATGATGQRLKEGAHINKSLVTLGSVISALAEQTGGGHNSSSSALATTPNGASKRVLYIPYRDS 319
            |::|||.|.||||||:|||||.|||.|||||||...|          |..|...|:..:||||||
 Frog   255 ADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSG----------TNKNKKKKKNDFIPYRDS 309

  Fly   320 ILTWLLKDSLGGNSKTIMIAALSPADCNYSETLSTLRYANRAKNIINKPTVNEDTNVKLIRELRE 384
            :|||||:::|||||:|.|:|||||||.||.|||||||||:|||.|.....:|||.|.:|||||::
 Frog   310 VLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAVINEDPNNRLIRELKD 374

  Fly   385 EINKLKSML----------------------------------------------------AGDI 397
            |:.:|:.:|                                                    |..:
 Frog   375 EVARLRDLLGAQGLSDIIDNVCPVDNGNVLHKRHAADNLFTAVNALTGMSPSSSMSGLSSRAASV 439

  Fly   398 HSLQPSLKVLAD----LQKKEAQEKV---LTEEWTEKWKVAQSILQEQKSL------GLRKSG-- 447
            .||...|.....    :::.:..||:   |.|.|.||.:..::|..::::|      .:|:.|
 Frog   440 TSLHERLAFTPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMDREALLAEMGVAMREDGGT 504

  Fly   448 VGVVLDSEMPHLIGIHND-VTTGVTLYSLKEGETRIGSEDADVAQDIELAGDGIRAQHC---SIF 508
            :||....:.|||:.::.| :.:...||.:|:|.||:|.|||.:.|||.|:|..||.:||   |..
 Frog   505 LGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGREDATMRQDIVLSGHFIRDEHCIFRSDV 569

  Fly   509 LKGG--VVTLHPWPLAQCWVNAHLIDEPKQISQGDIILLGRTNIFRFNNPAEAAKLRKDLSRSQL 571
            |..|  ||||.|...|..:||...:.:|..:..|:.|::|::::||||:|.:|.:.|:....::.
 Frog   570 LACGSVVVTLEPCDGADTYVNGKKLTDPCILRSGNRIIMGKSHVFRFNHPEQARQERERTPCAET 634

  Fly   572 DMSRLSLITSSKENLLTCSIYSDEDGASPYKRPERQYYPQRPMSRDDPELQDENRKILDTIENAL 636
            ....:....:.:|.|       ::.|..     .:|...||..     ||:|:.||..:.....|
 Frog   635 PSEPVDWAFAQRELL-------EKQGID-----MKQEMDQRLQ-----ELEDQYRKEREEANYLL 682

  Fly   637 KQ--------LNVERVQMHDQYKTKVRKLTEELIRLEQEEMDGLQLLNCREQELIARKDMLLWEK 693
            :|        |...:.||..:|.|:|   .||    |:|..|.:|   ..|||.    |:.||..
 Frog   683 EQQRLDYESRLEALQRQMDSRYFTEV---NEE----EEEPEDEVQ---WTEQEY----DLALWAF 733

  Fly   694 NNEKVQIDIVCRQISAFQTQLDSKKRDFSE--YVAKELQELQDCGKLDEMGMKIEEG--TPLNDE 754
            ...|      ..|.::.:.||........|  .::.||::     |:....:.:.:.  :||..:
 Frog   734 RKWK------WYQFTSLRDQLWGNAIFLKEANAISVELKK-----KVQFQFVLLTDTLYSPLPPD 787

  Fly   755 LL-------------------LQVSDSLDLFAAQFIKDTVRRNNEEIRKLDEQIAEKE------- 793
            ||                   ::|.|..:.....:..:.:|:..:.:|::.::.||..
 Frog   788 LLPPDAHTEREKRPFPRTIVAVEVQDQKNGATHYWTLEKLRQRLDMMREMYDRAAELPSGLTEDC 852

  Fly   794 -----------------RILNASTTKIAKVDETMLEIQAQLERLRLERAESEAESQAMRAKKQNM 841
                             |::.:|......:.|:|.||...   ..|....||....|.:.:::::
 Frog   853 DNVVTGGDPFYDRFPWFRLVGSSPLFTTCMSESMAEITPS---PTLSSPGSEGPEPASQLEEEDI 914

  Fly   842 KLQLGNKSMSTSTSTNEADDVSKSD---TYETC----DTFHTAQ-------------SNLSLVSS 886
                            ..||..:.|   .:..|    |.||...             ||| |.|.
 Frog   915 ----------------FQDDEEEDDGPQEHPCCAVRSDPFHDRSPLFSVVGRAFVYLSNL-LYSV 962

  Fly   887 PTI-------TEGQQSPLSNC---SCDAEDEAED----TRKDDLSGSSEET----------SRTC 927
            |.:       .:|:.......   :..|::||.|    .|:   ||:::.:          :.||
 Frog   963 PLVHRVAIVSEKGEVKGFLRVAVQAISADEEAPDYGSGVRQ---SGTAKISFDDQHFQKFQAETC 1024

  Fly   928 TAGPSSGSGSGSVGI--GGSGSAPSCTPSSQAIMSDSGVCLDSRNQAILQN------------GH 978
            .....||:....:.|  ||.|..|...||:..:  ::..|..|...::|.:            ||
 Frog  1025 PGMTRSGTSQEELRIVEGGQGQNPDSCPSADEV--NNNTCAASLQSSLLDSPTKPPFDLSDTMGH 1087

  Fly   979 ---------------------------------LNNYKQAVRTSD-EDTG--------------- 994
                                             ::.:.:|..|.. ::||
 Frog  1088 PLKLGSIFTFRVTVLQASSIPPEYADIFCQFNFIHRHDEAFSTEPLKNTGRGPPLGFYHVQNIAV 1152

  Fly   995 --SCSSCELGRHSDVA------------RPYC-----PLHSLRRKIAAQKALIMKNLETDLNKAQ 1040
              :.|..|..:...:.            .|.|     ||.|.||.:.....|......|.|::
 Frog  1153 EVTQSFVEYVKSQPIVFEVFGHYQQHPFPPLCKDVLSPLRSSRRLLPRVMPLSKPVPATKLSR-- 1215

  Fly  1041 LDEHIADLQDLQRRYIQMEQEMLQSVQDLEAHAQCCADERSG--------------MERQYELAS 1091
              :.:..:.....:|            ||.|:.|.|..|.:|              ....:.|..
 Frog  1216 --QRVPSVGPCHCKY------------DLMAYFQICELEANGDYIPVSVDHGVGLPCHGTFLLHQ 1266

  Fly  1092 SIMRSSVMSPTSMEESTSQI-YSPSMTRSCPSMREFPEGEHFITIPSFV---------------- 1139
            .|.|.  :|.|.:.|:.::: :..........:|..||.:..:..|:.:
 Frog  1267 GIQRR--ISVTLVHEAGAELKWLEVRELVVGRIRNTPEADESLIDPNILSLNILSAGYRPPEGGD 1329

  Fly  1140 -----------MRGAGKQTHYEYEVRIALPDGKLN---ILRRYSRFRE-------LHLCMKHCYG 1183
                       ..|.|.:|.|.:||..   |..::   :|.|.:.:||       .::.|::|
 Frog  1330 RQFLDSDTPSCQSGRGTRTFYHFEVAW---DSSMHNSLLLNRVTPYREKIYMTLSAYVEMENC-- 1389

  Fly  1184 AKISALPFPRRELFASNSEPVAKHRRRLLELYLRRLFVVCSKIPQCPIYEGPGGTGLTRAS 1244
                             ::|....:...:..|.|.     :|:|.|.......|||..|||
 Frog  1390 -----------------TQPAVITKDFCMVFYSRD-----AKLPACRSIRNLFGTGSLRAS 1428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp98A	NP_524532.2	KISc_KIF1A_KIF1B	2..371	CDD:276816	201/375 (54%)
		KISc	3..371	CDD:214526	201/374 (54%)
		Kinesin_assoc	370..478	CDD:292801	36/175 (21%)
		FHA	456..555	CDD:238017	41/104 (39%)
		PX_KIF16B_SNX23	1131..1259	CDD:132784	26/151 (17%)
kif1a	XP_031758411.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D76316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010