Protein Alignment CG12885 and LOC11175571

DIOPT Version :10

• Sequence 1: NP_001263012.2
• Gene: CG12885 / 43308
• FlyBaseID: FBgn0039523
• Length: 864
• Species: Drosophila melanogaster
• Sequence 2: XP_061505810.1
• Gene: LOC11175571 / 11175571
• VectorBaseID: AGAMI1_000604
• Length: 882
• Species: Anopheles gambiae
• Alignment Length: 1014
• Identity: 238/1014 - (23%)
• Similarity: 375/1014 - (36%)
• Gaps: 322/1014 - (31%)

  Fly    10 YKLQVELLQEKLQRSEDNRQQLEHKLDKILQKRTELDKSVRHKSRQKYQEFLEEQAKRNERNKKL 74
            |:.:.:.::.::::.|..|.:||.:.::::::|||.:|:.....:|:.:...|.:.:|.|||:.:
Mosquito    25 YRREFDEMEARIRKCERQRAELERQFEELMRERTECEKATVRAMKQRQRRQQEAERQRAERNESI 89

  Fly    75 VHMLERIDEQTAAMSQRSERLKMMKLQYQMYFAKLVQNQTLRCIQQTTTSTSA----PSAGGVIP 135
            :.||.:||:|.|:::.:::||||:|.||:||..:             |.|||:    |:|.|| |
Mosquito    90 LRMLNKIDQQAASLAAKTDRLKMLKTQYEMYLMR-------------TWSTSSGPALPAAYGV-P 140

  Fly   136 VLVQPQPQVTVTNPQSTPQNWTFAMATPTQAGMLLT----PQFAAASPAGPPMQPPTMPAGHPVY 196
            ::..| |.:....|||..::     :|.::....|:    .|.|:.:|..|||......|.....
Mosquito   141 MITAP-PAMLTPLPQSPAKS-----STKSEFVQYLSDLTHQQTASINPIPPPMALSNYLASQQKP 199

  Fly   197 YPELFAGTTAPLGTSNLFDLRATLRAFDN----ENADLPERMQPHLTGDYQAELGGRSQPSASAA 257
            |     |..:..|||.   .|...||:.:    ||..|                      ..::.
Mosquito   200 Y-----GMASTYGTSL---ERPYSRAYTSSAPIENDCL----------------------MVNSG 234

  Fly   258 AGPAAATPTSTLS------SQEKGAQQLSS--------TSSTLATSSLTFDKLPKTSSPSL---T 305
            ||.:.:|....:.      |.|...:.:.|        |.|.:|.|.:..||:.::....|   |
Mosquito   235 AGTSQSTTVGGIQAKKFAMSNEDFIRYIDSEVLKEPIPTVSIVAPSPVESDKVKQSGGAYLEDAT 299

  Fly   306 LTELPTAGVATPGHDVGGQPQRDAADLDGWTNSRVTKVEYEKSPTVVGHNEPGQEKQTLREQQHH 370
            ::|              .:|.|:.|:          |:| |.|..|    :|...|....|
Mosquito   300 MSE--------------DEPVREVAN----------KLE-EFSILV----DPDIRKDVTEE---- 331

  Fly   371 EPQQQHQQPSHDFEAYFGELKIDESSWQSGQ--PTPTPAPSGHEDKRPLNVRSSESGSGVGAGSA 433
            .|::..:..:...|:....:|..|:..|..:  ..||...|..:|.. .||             .
Mosquito   332 HPKEDIKVVAEMIESDHQNMKTPETIQQEKRSIELPTLVESVKDDNE-TNV-------------D 382

  Fly   434 VSGNVGISNDLLDEVKASRAALERAAAAVDEQLARGNQ--LSPPSSQDPKTGVSIENIENAIYGE 496
            :..|.|  |..||::...|...:......|.....||.  ::..:::|....:..|......||.
Mosquito   383 IDFNAG--NKTLDDMPDDRTHNDIQEILQDSTAPPGNDAVVNETANEDYHQTIHQEEYNETNYGV 445

  Fly   497 RLTGAAGAGAGLPA-----------AAVAGVASPEAMAAAPTKGFFDNLAANPS------PEEHQ 544
            ..         :||           |....:.:.|.....|    :|||....|      ||:..
Mosquito   446 EF---------VPANTNVDYDETTPATDQHLYTTEQTEHEP----YDNLQYGASIEPILNPEDTP 497

  Fly   545 EVEQQQ-----QQQQS-------------------------------TQQVEPELSGYGQYDASS 573
            |::.||     ||.:|                               |..|.|:|
Mosquito   498 EMDSQQLPQPVQQYESRNQHWNTARQALRSKALPVSSSKPPSPETGVTDHVAPDL---------- 552

  Fly   574 YGDASEPIYASIDSANQQPMQSAKVEPLY--------SEIGNP-ADYQHQSYATDAGAVAADVPA 629
                 :...|:.:||....|..|.|:|.|        ::|..| |.|      ::.|..|:|  |
Mosquito   553 -----QQGMATTESAETWRMDQADVQPPYENTQPNTVTQIDEPNATY------SEYGGEASD--A 604

  Fly   630 AVAVDGAATTLDASGAGEVLP----QEYSNIDYG---NYEAD--------QYAAGYDPNAYP--G 677
            ....:.||||....| ||:.|    |.|.|...|   .|:.|        ||....||.||.  .
Mosquito   605 YYQTEPAATTAVQDG-GELNPSSTDQAYINGAMGQPVEYQQDDGQQSAAYQYGNSQDPVAYQEGQ 668

  Fly   678 YIYDEATG----QYI--ADPNATQYATDGSYAGQD------YDASA-----VQNYDYSAYEQQPD 725
            |:..|..|    ||.  .|.....|||...|  ||      ||.:|     .|.||...|.|.|.
Mosquito   669 YVEGETAGESQYQYQEGVDQTGNVYATQEQY--QDPNQQYQYDQNAQYYSDQQAYDAQYYNQDPQ 731

  Fly   726 QQQQQEQQEMPVQEQLMQQEQQQQQEAYPETE--------ATPEVEESP-----------AAAAE 771
            ||:||:||    |:|....|..|||....:.|        .:||..:.|           |..||
Mosquito   732 QQEQQQQQ----QQQYYMDESNQQQMDQNQAEQLKPMDQFVSPEQNDQPYYPSDGQYEPNAKNAE 792

  Fly   772 P-------------PA----PLATSKPLKPTSILSTTDKQAAPNDAQQQQLKKKKRVNFVDSSET 819
            |             |:    |||.::.::..:::..|    .|.|.|:    ||.....|..:..
Mosquito   793 PTLPNPPEGGDVTVPSSLEPPLANAQTIETPAVIDAT----LPKDKQE----KKASDAIVQQATL 849

  Fly   820 DDSSSAKPTQAANPGPSAAPSPATPPAAGGSESDFDFST 858
            :...|.|  :.|:| .|.||:.:|.    ..|||||||:
Mosquito   850 EQKPSRK--EGADP-ESDAPTLSTV----NDESDFDFSS 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12885	NP_001263012.2	COG1340	4..>108	CDD:440951	30/97 (31%)
LOC11175571	XP_061505810.1	None