DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a18 and CYP97A3

DIOPT Version :9

Sequence 1:	NP_001287562.1	Gene:	Cyp6a18 / 43304	FlyBaseID:	FBgn0039519	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_564384.1	Gene:	CYP97A3 / 840067	AraportID:	AT1G31800	Length:	595	Species:	Arabidopsis thaliana

Alignment Length:	499	Identity:	111/499 - (22%)
Similarity:	191/499 - (38%)	Gaps:	115/499 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 YDKPHPLRGNMEGYKKTR---TVHEIHQEYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILI 97
            |.|....:|:::..:...   .::|:...|...:|.:..|        |....|.|..:||.||.
plant   110 YPKVPEAKGSIQAVRNEAFFIPLYELFLTYGGIFRLTFGP--------KSFLIVSDPSIAKHILK 166

  Fly    98 KNFSNFTDKGIYYNEKDDPMSAHLFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAV 162
            .|...:: |||.....|..|...|...||..||..|..:               |.::.::::|.
plant   167 DNAKAYS-KGILAEILDFVMGKGLIPADGEIWRRRRRAI---------------VPALHQKYVAA 215

  Fly   163 MHEKVSENS---------------ILDVRDLVARFTVDVIGTCAFGIKCNSLRDEKA--EFLHFG 210
            |.....|.|               .:::..|.:|.|:|:||...|....:||.::..  |.::..
plant   216 MISLFGEASDRLCQKLDAAALKGEEVEMESLFSRLTLDIIGKAVFNYDFDSLTNDTGVIEAVYTV 280

  Fly   211 RRALLD------------------SRHGNLVSGLMRSYPNLARRLGLCRNTAQIQE--FYQRIVK 255
            .|...|                  .|...:.:.|......|...:..|:...:.:|  |::..:.
plant   281 LREAEDRSVSPIPVWDIPIWKDISPRQRKVATSLKLINDTLDDLIATCKRMVEEEELQFHEEYMN 345

  Fly   256 ET------VTLREKENIK----RNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIA 310
            |.      ..|...:::.    |:|.|.||                                 ||
plant   346 ERDPSILHFLLASGDDVSSKQLRDDLMTML---------------------------------IA 377

  Fly   311 GFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTI 375
            |.:||::.:.:..|.|...||:..|::.|:..|:  .|:..|.:.:|.|||..:|:||:||.|..
plant   378 GHETSAAVLTWTFYLLTTEPSVVAKLQEEVDSVI--GDRFPTIQDMKKLKYTTRVMNESLRLYPQ 440

  Fly   376 VPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERF---SPEESAKRP 437
            .|.:.|.:....::...|   |:.|:.:.|....:|..|..:.:..:|.|||:   .|..:....
plant   441 PPVLIRRSIDNDILGEYP---IKRGEDIFISVWNLHRSPLHWDDAEKFNPERWPLDGPNPNETNQ 502

  Fly   438 SVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATP 481
            :.::||||.|||.|||..|...:..:.:||||:.|.|......|
plant   503 NFSYLPFGGGPRKCIGDMFASFENVVAIAMLIRRFNFQIAPGAP 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	110/497 (22%)
CYP97A3	NP_564384.1	PLN02738	1..595	CDD:215393	111/499 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810