DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a18 and CYP86B1

DIOPT Version :9

Sequence 1:	NP_001287562.1	Gene:	Cyp6a18 / 43304	FlyBaseID:	FBgn0039519	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_197710.1	Gene:	CYP86B1 / 832383	AraportID:	AT5G23190	Length:	559	Species:	Arabidopsis thaliana

Alignment Length:	539	Identity:	129/539 - (23%)
Similarity:	227/539 - (42%)	Gaps:	81/539 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 QVAVALLAIVTYILHRKLTYFKRRGIPY--------DKPHPLRGNMEGYKKTRTVHEIHQEYYNK 65
            |:...|:||..::....|...|.:|:|.        .....||||:             .|:.:.
plant    37 QILELLIAIFVFVAIHALRQKKYQGLPVWPFLGMLPSLAFGLRGNI-------------YEWLSD 88

  Fly    66 ---YRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEK-DDPMSAHLFNLDG 126
               .:|....|.|.:.....:....|....:.:|...||.| .||.|:.:. .|.:...:||.|.
plant    89 VLCLQNGTFQFRGPWFSSLNSTITCDPRNVEHLLKNRFSVF-PKGSYFRDNLRDLLGDGIFNADD 152

  Fly   127 PQWRLLRSKLSSTFTSGKMKFMYPTVVSVAE----EFMAVMHEKVSENSILDVRDLVARFTVDVI 187
            ..|:..|...|..|.|.  ||...|..|:.|    ..:.|:...|..:|.:|::|::.|.|.|.:
plant   153 ETWQRQRKTASIEFHSA--KFRQLTTQSLFELVHKRLLPVLETSVKSSSPIDLQDVLLRLTFDNV 215

  Fly   188 GTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRS-------YPNLARRLGLCRNTAQ 245
            ...|||:....|..:: ..:.|. :|..|:....:|..:|.:       |.::.....|..:...
plant   216 CMIAFGVDPGCLGPDQ-PVIPFA-KAFEDATEAAVVRFVMPTCVWKFMRYLDIGTEKKLKESIKG 278

  Fly   246 IQEFYQRIV---KETVTLREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVF 307
            :.:|...::   |:.::| |.|..||:|.:.:.:||:::|      ||......:.:|...   |
plant   279 VDDFADEVIRTRKKELSL-EGETTKRSDLLTVFMGLRDEK------GESFSDKFLRDICVN---F 333

  Fly   308 FIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHD-----QKFTYEC------IKDLKY 361
            .:||.||||..:.:..:.|.|||.:::|:..|:.::|.|.|     :|..||.      ||.:.|
plant   334 ILAGRDTSSVALSWFFWLLEKNPEVEEKIMVEMCKILRQRDDHGNAEKSDYEPVFGPEEIKKMDY 398

  Fly   362 LDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIY-PEPNEFRP 425
            |...::|.||.|..||...:...:..|.|...  :::.|..||....|:....:|: .:..||||
plant   399 LQAALSEALRLYPSVPVDHKEVQEDDVFPDGT--MLKKGDKVIYAIYAMGRMEAIWGKDCLEFRP 461

  Fly   426 ERFSPE-----ESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLT 485
            ||:..:     |||.:    :..|..|||.|:|..|...|.:...|.::..:.....:..    .
plant   462 ERWLRDGRFMSESAYK----FTAFNGGPRLCLGKDFAYYQMKSTAAAIVYRYKVKVVNGH----K 518

  Fly   486 FDPHSAILLGIKGGIQLKV 504
            .:|..|:.:.:|.|:.:.:
plant   519 VEPKLALTMYMKHGLMVNL 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	121/500 (24%)
CYP86B1	NP_197710.1	PLN03195	38..541	CDD:215627	128/538 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910