DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a18 and CYP97B3

DIOPT Version :9

Sequence 1:	NP_001287562.1	Gene:	Cyp6a18 / 43304	FlyBaseID:	FBgn0039519	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_193247.2	Gene:	CYP97B3 / 827177	AraportID:	AT4G15110	Length:	580	Species:	Arabidopsis thaliana

Alignment Length:	490	Identity:	122/490 - (24%)
Similarity:	203/490 - (41%)	Gaps:	99/490 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 PAAFVI--DLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFNLDGPQWRLLRSKLSSTFTSGK 144
            |.|||:  |..:|:.:|.:|..:: |||:.....:..|...|...|...|:|.|..::..|....
plant   120 PKAFVVISDPIIARHVLRENAFSY-DKGVLAEILEPIMGKGLIPADLDTWKLRRRAITPAFHKLY 183

  Fly   145 MKFMYPTVVSVAEEFMAVMHEKV--------SENSI-LDVRDLVARFTVDVIGTCAFGIKCNSLR 200
            ::.|. .|.|...|.|.:..||:        .|::| ||:....:...:|:||...|.....|:.
plant   184 LEAMV-KVFSDCSEKMILKSEKLIREKETSSGEDTIELDLEAEFSSLALDIIGLSVFNYDFGSVT 247

  Fly   201 DEKAEFLHFGRRALLDSRHGNLVSGLMRS-----YPNL--ARRL-------------------GL 239
            .|.         .::.:.:|.|.....||     |.|.  ||.:                   ||
plant   248 KES---------PVIKAVYGTLFEAEHRSTFYFPYWNFPPARWIVPRQRKFQSDLKIINDCLDGL 303

  Fly   240 CRNTAQIQEFYQRIVKETVTLREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMD--EIVA 302
            .:|.   :|..|....|.:..|:..|:|....:..|:.:              :|:.:|  ::..
plant   304 IQNA---KETRQETDVEKLQERDYTNLKDASLLRFLVDM--------------RGVDIDDRQLRD 351

  Fly   303 QAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVIN 367
            ......|||.:|:::.:.:|::.|::||....|.:||:..||.|...  |||.:|.|:|:..::.
plant   352 DLMTMLIAGHETTAAVLTWAVFLLSQNPEKIRKAQAEIDAVLGQGPP--TYESMKKLEYIRLIVV 414

  Fly   368 ETLRHYTIVPNVDRVAAKRFVVPGNPK-----FVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPER 427
            |.||.:...|.:.|...|...:||..|     ..:..|..:.|....:|..|..:..|::|.|||
plant   415 EVLRLFPQPPLLIRRTLKPETLPGGHKGEKEGHKVPKGTDIFISVYNLHRSPYFWDNPHDFEPER 479

  Fly   428 ---------------FSPEES--AKRPS-----VAWLPFGEGPRNCIGLRFGQMQARIGLAMLIK 470
                           |.|..|  |..|:     .|:||||.|||.|||.:|..|::.:.||||.:
plant   480 FLRTKESNGIEGWAGFDPSRSPGALYPNEIIADFAFLPFGGGPRKCIGDQFALMESTVALAMLFQ 544

  Fly   471 NFTFSPCSATPDPLTFDPHSAILLGIKGGIQLKVE 505
            .|... ...||:  :.:..|...:..|.|:..|::
plant   545 KFDVE-LRGTPE--SVELVSGATIHAKNGMWCKLK 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	121/487 (25%)
CYP97B3	NP_193247.2	PLN02738	45..580	CDD:215393	122/490 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810