DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a18 and CYP705A23

DIOPT Version :9

Sequence 1:	NP_001287562.1	Gene:	Cyp6a18 / 43304	FlyBaseID:	FBgn0039519	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_188649.1	Gene:	CYP705A23 / 821557	AraportID:	AT3G20140	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	517	Identity:	117/517 - (22%)
Similarity:	200/517 - (38%)	Gaps:	109/517 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LFQVAVALLAIVTYILHRKLTYFKRRGIPYD----KPHPLRGNMEGYKK---TRTVHEIHQEYYN 64
            |..:.:.:|.::.|.|     :||:..:..|    .|.||...:.|:..   :...|:..|:..:
plant    13 LIFILLCILLLLCYPL-----FFKKPKVSQDGFGLPPSPLSLPIIGHLHLLFSNLTHKSLQKLSS 72

  Fly    65 KYRNSKAPFVGFYLFQKPAAFVIDLELAKQI--------------------LIKNFSNFT-DKGI 108
            ||    .|.:...:|..|..||....:|.:|                    |:.:|..|| ..|.
plant    73 KY----GPLLYLRIFNVPIIFVSSASVAYEIFRGHDVNISFRGNPPIEESLLVGSFGFFTAPYGD 133

  Fly   109 YYNEKDDPMSAHLFNLDGPQWRLLRSK------LSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKV 167
            |:......|...|.   ||| .|.||:      |...:.:...|.|....|.:.:|.|.::::.:
plant   134 YWKFMKKVMVTKLL---GPQ-ALQRSRGIRADALERFYMNLLDKAMKKESVEIGKETMKLIYDSI 194

  Fly   168 ----------SENSILD-VRDLVARFTVDVIGTCAFGIKCNSLRDE--KAEFLHFGRRALLDSRH 219
                      .||...: ||.||...|              :|..:  .|..||...:.|..|..
plant   195 CKMIMGRNFSEENGEAERVRGLVTEST--------------ALTKKIFMANVLHKPLKKLGISLF 245

  Fly   220 GNLVSGLMRSYPNLARRLGLCRNTAQIQEFYQRIVKETVTLREKENIKRNDFMDMLIGLKNQKNM 284
            ...:..:..|:..|..|.               :|:....|.|.:::   |.|.:|:.....||.
plant   246 KKEIMDVSNSFDELLERF---------------LVEHEEKLNEDQDM---DMMGVLLAACRDKNA 292

  Fly   285 TLE-NGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHD 348
            ..: ....:|.|.:|.:|        ||.|||.....:.:.|:...|.:.:|||.|:..|:.:
plant   293 ECKITRNHIKSLFVDLVV--------AGTDTSRHATQWTMAEIINKPKVLEKVREEIYSVVGR-- 347

  Fly   349 QKFTYEC-IKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHH 412
            .:...|. :..|.||...:.|.||.:...|...|.|.:.|.|.|   |.:.....:::.:.|:..
plant   348 TRLVQETDLPSLPYLQATVKEGLRLHPPGPLFARTAREGFSVGG---FYVPENTPLVVNAYAMMR 409

  Fly   413 DPSIYPEPNEFRPERF--SPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNF 472
            ||..:.:||||:||||  |.:|..:...:.::|||.|.|.|.|:....:.....:.::::.|
plant   410 DPGSWEDPNEFKPERFLGSGKEDEREHGLKYIPFGSGRRGCPGINLAYILVGTAIGVMVQCF 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	110/482 (23%)
CYP705A23	NP_188649.1	p450	26..504	CDD:386267	115/504 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010