DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cyp6a18 and CYP72A8

DIOPT Version :9

Sequence 1:NP_001287562.1 Gene:Cyp6a18 / 43304 FlyBaseID:FBgn0039519 Length:507 Species:Drosophila melanogaster
Sequence 2:NP_188080.1 Gene:CYP72A8 / 820690 AraportID:AT3G14620 Length:515 Species:Arabidopsis thaliana


Alignment Length:558 Identity:135/558 - (24%)
Similarity:238/558 - (42%) Gaps:123/558 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 VAVALLAIVTYIL-------------HRKLTYFKRRGI---PY----------------DKPHPL 42
            ||.|::.:.|..:             .:...|.||:|:   |:                :|..|:
plant    11 VAAAVVVVTTVTVWIWKGLNVAWLRPKKNEAYLKRQGLSGTPFTFLVGDIKREASMVEQEKSRPI 75

  Fly    43 RGNMEGYKKTRTVHEIHQEYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKG 107
              |:......|.:..|.|...:..:.|       |::..|.|.||   :.|...||:..|..   
plant    76 --NLTDDYTHRVMPLIQQTVKDHGKTS-------YMWMGPIASVI---VTKPEHIKDVLNRV--- 125

  Fly   108 IYYNEKDDPMS--AHLFN-----LDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHE 165
              |:....|:.  ..||.     .:|.:|...|..::.:|...|:|.|.|.......|.::...:
plant   126 --YDFPKPPVHPIVELFATGVALYEGEKWSKHRKIINPSFHLEKLKIMIPAFYESCSEMISKWEK 188

  Fly   166 KVSE---NSILDVRDLVARFTVDVIGTCAFGI------KCNSLRDEKAEFLHFGRRALLDSRHGN 221
            .|:|   ::.:||...:...|.|||...|||.      :...|::|:      ||| :|.:....
plant   189 LVTEQGSSNEIDVWPYLGDLTSDVISRTAFGSSYEEGKRIFELQEEQ------GRR-VLKALELA 246

  Fly   222 LVSGLMRSYP---NLARRLGLCRNTAQIQEFYQRIVKETVTLREK----ENIKRNDFMDMLIGLK 279
            .:.| ||..|   ||..|        ||.:..:..::|.:..|::    ....:||.:.:|    
plant   247 FIPG-MRFLPTKNNLRMR--------QINKEVKSRLREIIMKRQRGMDTGEAPKNDLLGIL---- 298

  Fly   280 NQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVL 344
                  ||:.....|::::::|.:..:|..||.:|::..:.:.:..|:.:...||:.|.|:.:|:
plant   299 ------LESNSGDHGMSIEDVVEECRLFHFAGQETTAVLLVWTMIMLSHHQKWQDQAREEILKVI 357

  Fly   345 EQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKR------FVVPGNPKFVIEAGQSV 403
            .::: |..::.:..||.:..::||.||.|.....:.|...|.      ..:||        |..|
plant   358 GKNN-KPNFDALSRLKTMSMILNEVLRLYPPGILLGRTVEKETKLGEDMTLPG--------GAQV 413

  Fly   404 IIPSSAIHHDPSIYPEP-NEFRPERFSPEES-AKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLA 466
            :||...:|.||.::.|. :||.||||:...| |.:..|::||||.|||.|.|..|..|:|::.|.
plant   414 VIPVLMVHRDPELWGEDVHEFNPERFADGISKATKNQVSFLPFGWGPRFCPGQNFALMEAKMALV 478

  Fly   467 MLIKNFTF--SPCSATPDPLTFDPHSAILLGIKGGIQL 502
            ::::.|:|  ||      ..|..||:.:.|..:.|..|
plant   479 LILQRFSFELSP------SYTHAPHTVLTLHPQFGAPL 510

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cyp6a18NP_001287562.1 p450 38..504 CDD:278495 126/498 (25%)
CYP72A8NP_188080.1 p450 26..515 CDD:299894 131/543 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm3438
orthoMCL 1 0.900 - - OOG6_100014
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.900

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