Protein Alignment Cyp6a18 and Cyp4x1

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001003947.1
• Gene: Cyp4x1 / 81906
• MGIID: 1932403
• Length: 507
• Species: Mus musculus
• Alignment Length: 537
• Identity: 140/537 - (26%)
• Similarity: 253/537 - (47%)
• Gaps: 87/537 - (16%)

  Fly     7 LFQVAVALL-AIVTYILHRKLTYFKRRGIPYDKP--HPLRG--------NMEGYKKTRTVHEIHQ 60
            :|.:|:.|: |:..|:..::|.   |...|:..|  |.|.|        |||      |:.||.:
Mouse    19 VFCLALVLMQAMKLYLRRQRLL---RDLSPFPGPPAHWLLGHQKFLQEDNME------TLDEIVK 74

  Fly    61 EYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTD-KGIYYNEKDDP-MSAHLFN 123
            ::...:.....||..|:       ::.|.:.||..|.:     || |..|.::...| :...|.|
Mouse    75 KHPCAFPCWVGPFQAFF-------YIYDPDYAKIFLSR-----TDPKMQYLHQLLTPCIGRGLLN 127

  Fly   124 LDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEK-----VSENSILDVRDLVARFT 183
            ||||:|...|..|:..|....:|   |.|.::|.. :.||.:|     .::.:.::|.:.:...|
Mouse   128 LDGPRWFQHRCLLTPAFHQDILK---PCVDTMAHS-VKVMLDKWEKMWTTQETTIEVFEHINLMT 188

  Fly   184 VDVIGTCAFGIKCNSLRD------EKAEFLHFGRRALLDSR------HGNLVSGLMRSYPNLARR 236
            :|:|..||||.:.|...:      .||.| ..|.  ::.||      |.:::..|... .:..:.
Mouse   189 LDIIMKCAFGQETNCQINGTYESYVKATF-ELGE--IISSRLYNFWHHHDIIFKLSPK-GHCFQE 249

  Fly   237 LGLCRNTAQIQEFYQRIVKETVTLREKENIKRND------FMDMLIGLKNQKNMTLENGEVVKGL 295
            ||     ..|.::.::|:::...:. |..:|::|      |:|:::..:.:......:.
Mouse   250 LG-----KVIHQYTEKIIQDRKKIL-KNQVKQDDTQTSQIFLDIVLSAQAEDERAFSDA------ 302

  Fly   296 TMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLK 360
               ::.|:...|..||.|.|::::.:.||.||.||..||:.|.|:..:|.. ....|:|.:.::.
Mouse   303 ---DLRAEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTEIRSILGD-GSSITWEQLDEMS 363

  Fly   361 YLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRP 425
            |....|.||||....||::.|..:|...:|....  :.||.:|::....:||:|:::.:|..|.|
Mouse   364 YTTMCIKETLRLIPPVPSISRELSKPLTLPDGHS--LPAGMTVVLSIWGLHHNPAVWNDPKVFDP 426

  Fly   426 ERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHS 490
            .||:.|.|.:|...|:|||..|||||||.:|..::.::.:|:::.:|..:|....|.  .|..|:
Mouse   427 LRFTKENSDQRHPCAFLPFSSGPRNCIGQQFAMLELKVAIALILLHFQVAPDLTRPP--AFSSHT 489

  Fly   491 AILLGIKGGIQLKVEAI 507
              :|..|.||.|.::.:
Mouse   490 --VLRPKHGIYLHLKKL 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	119/454 (26%)
Cyp4x1	NP_001003947.1	CYP4B-like	66..500	CDD:410771	126/481 (26%)