Protein Alignment Cyp6a18 and cyp11a1.1

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_694485.2
• Gene: cyp11a1.1 / 80374
• ZFINID: ZDB-GENE-010306-1
• Length: 509
• Species: Danio rerio
• Alignment Length: 513
• Identity: 120/513 - (23%)
• Similarity: 203/513 - (39%)
• Gaps: 128/513 - (24%)

  Fly    63 YNK----YRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEK---------- 113
            :||    :|||   .:....|.|...    |....:|::.||..|   |..|.||
Zfish    41 FNKIPGRWRNS---LLSVLAFTKMGG----LRNVHRIMVHNFKTF---GPIYREKVGIYDSVYII 95

  Fly   114 --DDPMSAHLF----------NLD-------------------GPQWR---------LLRSKLSS 138
              :|  .|.||          |:|                   |..|:         ||..||..
Zfish    96 KPED--GAILFKAEGHHPNRINVDAWTAYRDYRNQKYGVLLKEGKAWKTDRMILNKELLLPKLQG 158

  Fly   139 TFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENS----ILDVRDLVARFTVDVIGTCAFGIKCNSL 199
            ||.        |.:..|.::|:|.:::::..:.    ..|:...:.:|:::.:....:|.:...|
Zfish   159 TFV--------PLLEEVGQDFVARVNKQIERSGQKQWTTDLTHDLFKFSLESVSAVLYGERLGLL 215

  Fly   200 RDE-KAEFLHFGRRALLD--SRHGNLVSGLMRSYPNLARRLG--LCRNTA--------QIQEFYQ 251
            .|. ..||.||     :|  |......|.::...|.|.|.:|  :.:|..        |...:.|
Zfish   216 LDNIDPEFQHF-----IDCVSVMFKTTSPMLYLPPGLLRSIGSNIWKNHVEAWDGIFNQADRYIQ 275

  Fly   252 RIVKETVTLREKENIKRN-DFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTS 315
            .|.|:.     |||.:.| .:..:|..|..|..:::|           :|.|........|.|:.
Zfish   276 NIFKQW-----KENPEGNGKYPGVLAILLMQDKLSIE-----------DIKASVTELMAGGVDSV 324

  Fly   316 SSTMGFALYELAKNPSIQDKVRAEL--GQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPN 378
            :.|:.:.|||||:.|.:||::|||:  .::..:.|.   .:.:|.:..|...:.||||.:.:..:
Zfish   325 TFTLLWTLYELARQPDLQDELRAEISAARIAFKGDM---VQMVKMIPLLKAALKETLRLHPVAMS 386

  Fly   379 VDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLP 443
            :.|...:..|:   ..:.|.||..|.:...|:..|...:|:|.::.|.|:.   |:||.....|.
Zfish   387 LPRFITEDTVI---QNYHIPAGTLVQLGVYAMGRDHQFFPKPEQYCPSRWI---SSKRQYFKSLG 445

  Fly   444 FGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFD----PHSAILLGIK 497
            ||.|||.|:|.|..:.:.:|.|..:::||.............|:    |...|:|.||
Zfish   446 FGFGPRQCLGRRIAETEMQIFLIHMLENFRIEKQKQIEVRSKFELLLMPEKPIMLTIK 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	115/502 (23%)
cyp11a1.1	NP_694485.2	cytochrome_P450	75..498	CDD:477761	106/465 (23%)