Protein Alignment Cyp6a18 and cyp26b1

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001072655.1
• Gene: cyp26b1 / 780112
• XenbaseID: XB-GENE-991500
• Length: 511
• Species: Xenopus tropicalis
• Alignment Length: 475
• Identity: 115/475 - (24%)
• Similarity: 192/475 - (40%)
• Gaps: 63/475 - (13%)

  Fly    10 VAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIHQ--EYYNKYRNSKAP 72
            |:||||..|:..|. :|.:...|......|.| :|:|.......|.|.|.|  ::.:..|.....
 Frog    20 VSVALLLAVSQQLW-QLRWAATRDKSCKLPIP-KGSMGFPLVGETFHWILQGSDFQSSRREKYGN 82

  Fly    73 FVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDD-PMSAH-------LFNLDGPQW 129
            ....:|..:|...|...|..::||:         |.::....: |.|..       |.|..|...
 Frog    83 VFKTHLLGRPLIRVTGAENVRKILM---------GEHHLVSTEWPRSTRMLLGPNSLANSIGDIH 138

  Fly   130 RLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEK-VSENSILDVRDLVARFTVDVIGTCAFG 193
            |..|...|..|:...::...|.:..|.::.:.|.... .|.|...:.:.|..|..:.|:    .|
 Frog   139 RHKRKVFSKIFSHEALESYLPKIQLVIQDTLRVWSSNPESINVYCEAQKLTFRMAIRVL----LG 199

  Fly   194 IKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGLCRNTAQIQEFYQRIVKETV 258
            .:   |.||:...|....:..:::     |..|....|....|.|: |....:.:..::.::|.:
 Frog   200 FR---LSDEELSQLFQVFQQFVEN-----VFSLPVDVPFSGYRRGI-RAREMLLKSLEKAIQEKL 255

  Fly   259 TLREKENIKRNDFMDMLIGLKNQKNMTLENG-EVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFA 322
                 :|.:..|:.|.|       ::.:|:| |..|.|||.|:.........|.:.|::|.....
 Frog   256 -----QNTQGKDYADAL-------DILIESGKEHGKELTMQELKDGTLELIFAAYATTASASTSL 308

  Fly   323 LYELAKNPSIQDKVRAEL--------GQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNV 379
            :.:|.|:||:.:|:|.||        |.|.|   .....|.|..|.|||.||.|.||.::.|...
 Frog   309 IMQLLKHPSVLEKLREELRGNSILHNGCVCE---GALRVETISSLHYLDCVIKEILRLFSPVSGG 370

  Fly   380 DRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESA-KRPSVAWLP 443
            .|...:.|.:.|   |.|..|.||:......|....::.:.:.|.|:||..:.:. |.....:||
 Frog   371 YRTVLQTFELDG---FQIPKGWSVLYSIRDTHDTAPVFKDVDVFDPDRFGQDRTEDKDGRFHYLP 432

  Fly   444 FGEGPRNCIGLRFGQMQARI 463
            ||.|.|||:|....::..::
 Frog   433 FGGGVRNCLGKHLAKLFLKV 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	97/413 (23%)
cyp26b1	NP_001072655.1	CYP26B1	60..489	CDD:410730	102/433 (24%)