Protein Alignment Cyp6a18 and Cyp4f37

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001093657.1
• Gene: Cyp4f37 / 677156
• MGIID: 3780112
• Length: 546
• Species: Mus musculus
• Alignment Length: 548
• Identity: 146/548 - (26%)
• Similarity: 243/548 - (44%)
• Gaps: 105/548 - (19%)

  Fly    14 LLAIVTYILHRKL--TY------FKRRGIPYDKPHPLRG-----------NMEGYKKTRTVHEIH 59
            ||...::||.|.|  ||      .:.|..|  :| |.|.           |.||   .:.:.|..
Mouse    23 LLGAASWILARILAWTYSFCENCSRLRCFP--QP-PKRNWFLGHLGMIEHNEEG---MQLMTEAG 81

  Fly    60 QEYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNF-------TDKGIYYNEKDDPM 117
            |.|.:.:.....|.:.......| |||..|.||..::....:.|       ...|::.|
Mouse    82 QTYRDVHLCWLGPVIPVLRIVDP-AFVAPLLLASALVAPKDTTFHTFVKPWLGDGLFLN------ 139

  Fly   118 SAHLFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEK----VSENSI-LDVRD 177
                   .|.:|...|..|:..|....:|    ..|.:..:.:.:||.|    .||.|. |::.:
Mouse   140 -------SGDKWSRHRRLLTPAFHFDILK----PYVKIFNQSVNIMHAKWKHLSSEGSARLEMFE 193

  Fly   178 LVARFTVDVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGLCRN 242
            .::..|:|.:..|.||...| .::..:|::    .|:|:.  .:||  :.||:........|..:
Mouse   194 HISLMTLDSLQKCLFGFDSN-CQESPSEYI----SAILEL--SSLV--IKRSHQLFLFVDFLYYH 249

  Fly   243 TAQ----------IQEFYQRIVKE---TVT-------LREKENIKRNDFMDMLIGLKNQKNMTLE 287
            ||.          :..|...:::|   |::       |:.|...|..||:|:|:..|:      |
Mouse   250 TADGRRFRKACDLVHNFTDAVIRERRHTLSSQNHDEFLKSKTKSKTLDFIDVLLLAKD------E 308

  Fly   288 NGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLE-QHDQKF 351
            :|   |.|:.::|.|:|..|...|.||::|.:.:.||.||::|..|::.|.|:.::|. :..|:.
Mouse   309 HG---KELSDEDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVQELLRGREPQEI 370

  Fly   352 TYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSI 416
            .::.:..|.:|...|.|:||.:..|.::.|...:..|:|...  ||..|...:|....|||:||:
Mouse   371 EWDDLAQLPFLTMCIKESLRLHPPVIDLLRRCTRDIVLPDGR--VIPKGNICVISIFGIHHNPSV 433

  Fly   417 YPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATP 481
            :|:|..:.|.||.||.:.|||.:|::||..|||||||..|...:..:.||:.:..|...|....|
Mouse   434 WPDPEVYDPFRFDPENAHKRPPLAFIPFSAGPRNCIGQTFAMNEMMVALALTLLRFRILPDDKEP 498

  Fly   482 --DPLTFDPHSAILLGIKGGIQLKVEAI 507
              .|       .|:|..:||:.|:||.:
Mouse   499 RRKP-------EIILRAEGGLWLRVEPL 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	123/464 (27%)
Cyp4f37	NP_001093657.1	CYP4F	74..515	CDD:410772	127/485 (26%)