Protein Alignment Cyp6a18 and Cyp4f14

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_071879.1
• Gene: Cyp4f14 / 64385
• MGIID: 1927669
• Length: 524
• Species: Mus musculus
• Alignment Length: 534
• Identity: 137/534 - (25%)
• Similarity: 237/534 - (44%)
• Gaps: 83/534 - (15%)

  Fly    12 VALLAIVTYILHRKLTYFKRRGIPY-DKPHPLRGNM-------EGYKK-TRTVHEIHQEYYNKYR 67
            :|.:.|..|..:|  .|....|.|. .|.:.|.|::       :|.|: ||.|....|
Mouse    31 LARILIQIYAAYR--NYRHLHGFPQPPKRNWLMGHVGMVTPTEQGLKELTRLVGTYPQ------- 86

  Fly    68 NSKAPFVGFYLFQKPAAFVIDL---ELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFNLDGPQW 129
                   ||.::..|...||.|   ::.:.||..:.:......|:|:.....:...|....|.:|
Mouse    87 -------GFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYSILKPWLGDGLLVSAGDKW 144

  Fly   130 RLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEK----VSENSI-LDVRDLVARFTVDVIGT 189
            ...|..|:..|....:|    ..|.:..:...:||.|    :|:.|. ||:.:.|:..|:|.:..
Mouse   145 SRHRRMLTPAFHFNILK----PYVKIFNDSTNIMHAKWQRLISDGSARLDMFEHVSLMTLDSLQK 205

  Fly   190 CAFGIKCNSLRDEKAEFLH--FGRRALLDSRHGN---LVSGLMRSYPNLARRLGLCRNTAQIQEF 249
            |.|....| .:::.:|::.  ....||:..||..   .:..|....|:..|....|.   .:.||
Mouse   206 CVFSFDSN-CQEKSSEYIAAILELSALVAKRHQQPLMFMDLLYNLTPDGMRFRKACN---VVHEF 266

  Fly   250 YQRIVKE---TVT-------LREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQA 304
            ...:::|   |:.       |:.|...|..||:|:|:..|:      |:|   |.|:.::|.|:|
Mouse   267 TDAVIRERHRTLPDQGLDDFLKSKAKSKTLDFIDVLLLSKD------EDG---KELSDEDIRAEA 322

  Fly   305 FVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLE-QHDQKFTYECIKDLKYLDQVINE 368
            ..|...|.||::|.:.:.||.||::|..|::.|.|:.::|. :..::..::.:..|.:|...|.|
Mouse   323 DTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVQELLRGREPEEIEWDDLAQLPFLTMCIKE 387

  Fly   369 TLRHYTIVPNVDRVAAKRFVVPGN---PKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSP 430
            :||.:..|..:.|...:..::|..   ||.:|     .:|....|||:||::|:|..:.|.||.|
Mouse   388 SLRLHPPVTVISRCCTQDILLPDGRTIPKGII-----CLISIFGIHHNPSVWPDPEVYDPFRFDP 447

  Fly   431 EESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATP--DPLTFDPHSAIL 493
            |.......:|::||..|||||||..|...:.::.||:.:..|...|....|  .|       .::
Mouse   448 ENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRLLPDDKEPRRQP-------ELI 505

  Fly   494 LGIKGGIQLKVEAI 507
            |..:||:.|:||.:
Mouse   506 LRAEGGLWLRVEPL 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	117/458 (26%)
Cyp4f14	NP_071879.1	CYP4F	74..515	CDD:410772	123/483 (25%)