Protein Alignment Cyp6a18 and cyp46a1.5

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001417768.2
• Gene: cyp46a1.5 / 641477
• ZFINID: ZDB-GENE-051120-33
• Length: 501
• Species: Danio rerio
• Alignment Length: 548
• Identity: 144/548 - (26%)
• Similarity: 227/548 - (41%)
• Gaps: 112/548 - (20%)

  Fly     3 LTYFLFQVAVALLAIVTYI--LHRKLTYFKRRGIPYDK-PHPLRGN-MEGYKKTRT--------- 54
            :.|.|..|..|..|...|:  :|:|          ||. |.|.|.| :.|:..:.|
Zfish    10 ILYLLAAVFTAFFAYCLYVHHIHQK----------YDHIPGPPRDNFLLGHSPSLTKALYSDDSL 64

  Fly    55 VHEIHQEYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSA 119
            ::::..::..||    .|.............|...|..|.|::.  ..:|        ||..:..
Zfish    65 IYDLFLQWAEKY----GPVYRINTLHYVTIVVYCPEATKTIMMS--PKYT--------KDPFVYR 115

  Fly   120 HLFNLDGPQ--------------WRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSEN 170
            .:|||.|.:              |...|..:...|:|..::.:..|...::|..|..:.|..:..
Zfish   116 RVFNLFGKRFLGYGLITAVDHDIWYRQRRIMDPAFSSSYLRSLISTFDEMSERLMDKLEEIANNK 180

  Fly   171 SILDVRDLVARFTVDVIGTCAFGIKCNSLRDEKAEFLHFGRRAL----LDSRHGNLVSGLMRSYP 231
            :...:.|||...|:|||...|||:..|.|..:.:.|.:.....|    .|.|     ..|.|..|
Zfish   181 TPAVMHDLVNCVTLDVICKVAFGVDLNFLTQKDSPFQNAVELCLKGMTFDVR-----DPLFRIIP 240

  Fly   232 NLARRLGLCRNTAQIQEFYQRIVKETVTLREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLT 296
                     :|...||:     |:|...|..|...|         .::|:|. .::|||.|....
Zfish   241 ---------KNWKLIQQ-----VREATELLRKTGEK---------WIQNRKT-AVKNGEDVPKDI 281

  Fly   297 MDEIVAQA-----------------FV-FFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQV 343
            :.:|:..|                 || ||:||.:|:::.:.||:.||.:||.|..:.:||:.:|
Zfish   282 LTQILKSAEEQNVTSTEDFEQMLDNFVTFFMAGQETTANQLSFAIMELGRNPEIYKRAKAEVDEV 346

  Fly   344 LEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSS 408
            |.. .::.:.|.:..|.||.||:.||||.|...|..:|...:..|:.|   ..|..|.||:..|.
Zfish   347 LGT-KREISNEDLGKLTYLSQVLKETLRLYPTAPGTNRWLHEDMVING---IKIPGGCSVMFNSF 407

  Fly   409 AIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFT 473
            ........:.:|.:|.|:||  :|:|.:|...:.||..|||.|||..|.||:|::.||.|::.|.
Zfish   408 VSQRLEKFFKDPLKFDPKRF--DENAPKPYYTYYPFALGPRTCIGQVFSQMEAKVVLAKLLQRFE 470

  Fly   474 FS--PCSA--TPDPLTFDPHSAILLGIK 497
            ||  |..:  ..|..|..|.|.::..||
Zfish   471 FSLVPGQSFDIKDTGTLRPKSGVICYIK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	126/468 (27%)
cyp46a1.5	NP_001417768.2	None