Protein Alignment Cyp6a18 and cyp3c4

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001071016.1
• Gene: cyp3c4 / 558541
• ZFINID: ZDB-GENE-060929-96
• Length: 507
• Species: Danio rerio
• Alignment Length: 515
• Identity: 159/515 - (30%)
• Similarity: 267/515 - (51%)
• Gaps: 46/515 - (8%)

  Fly     1 MQLTYFLFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIHQEYYNK 65
            :.:|:.|..:.:.||.|.....||   :|.:.|||..:|.|..|.:..|.|  .:.....|...|
Zfish     7 LSVTWTLVVLVITLLFIYGVWPHR---FFIKLGIPGPRPWPFVGTLLSYAK--GLCNFDMECAKK 66

  Fly    66 YRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKN-FSNFTDKGIYYNEKDDPMSAHLFNLDGPQW 129
            |    ....|.|..:.|...|.|||:.|.:|:|. :|||.::.........|.|..:..:...:|
Zfish    67 Y----GKVWGIYDGRLPILMVADLEVIKVVLVKECYSNFINRRKRTTGLAGPFSDGIIMVKDERW 127

  Fly   130 RLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDVIGTCAFGI 194
            :.:||.||..||||::|.::|..::.|:.|:..|.:|..|..: .::::||.:::|||.:.:|.:
Zfish   128 KRMRSTLSPYFTSGRLKEIFPIAMTHADRFIKNMQKKDPEQPV-KIKEVVAPYSLDVITSSSFSV 191

  Fly   195 KCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLA---RRLGLCRNTAQIQEFYQRIVKE 256
            ..:|:.:.:..|: ...:..:.....|.:..|:..:|:||   :::|:...:....:|:..::|:
Zfish   192 DIDSINNPEDPFV-INVKKFIQFNMFNPLLLLILLFPSLAIPLKKMGVTLFSKSAMDFFYSVLKK 255

  Fly   257 TVTLREKENIKRNDFMDMLIGLKN-------QKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDT 314
            ......||:..|.||:.::  |:|       |.:.|.|  :..||||..||::|:.||.:.|::|
Zfish   256 IKDDHNKESEGRVDFLKLM--LQNQIPDDQIQDSDTSE--QPAKGLTDHEILSQSLVFILGGYET 316

  Fly   315 SSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKF------TYECIKDLKYLDQVINETLRHY 373
            :|:|:.|.||.||.||...:|       ::|:.|:.|      ||:.:..:.||:..|||::|..
Zfish   317 TSTTLTFLLYNLATNPDCLEK-------LVEEIDKNFPLDTPITYDALMRMDYLEMAINESMRLL 374

  Fly   374 TIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPS 438
            ...|.::|.|.|..|:.|   ..|..|..|.||:..:.|||.|:..|.||||||||||..::...
Zfish   375 PTAPRLERSAKKTVVING---LTIPEGTLVGIPTYVLSHDPDIWESPGEFRPERFSPENKSEFLQ 436

  Fly   439 VAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPL----TFDPHSAILL 494
            .|::|||.|||||||:|:..|..::.:..|::||:...|..|..||    ||.|...|.|
Zfish   437 YAFIPFGLGPRNCIGMRYAVMIMKLFVVKLLQNFSVETCKETQIPLEMNVTFQPKVPITL 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	140/446 (31%)
cyp3c4	NP_001071016.1	cytochrome_P450	66..497	CDD:477761	142/451 (31%)