Protein Alignment Cyp6a18 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001025122.2
• Gene: cyp26c1 / 554036
• ZFINID: ZDB-GENE-050714-2
• Length: 554
• Species: Danio rerio
• Alignment Length: 526
• Identity: 113/526 - (21%)
• Similarity: 187/526 - (35%)
• Gaps: 126/526 - (23%)

  Fly     7 LFQVAVALLAIVTYILHRKLTYFKRRGIPYDK----PHPLRGNMEGYKKTRTVHEIHQ--EYYNK 65
            |..||.|:|..|..:...:|.:..|..|..|:    |.| :|:|.......|.|.:.|  .::..
Zfish    12 LLSVADAVLPTVLLLAVSRLLWEFRWSITRDRTCKLPLP-QGSMGWPLVGETFHWLFQGSSFHIS 75

  Fly    66 YRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAH-------LFN 123
            .|.........:|..||...|...|..::||:...:....:.        |.|..       |.|
Zfish    76 RREKHGKVFKTHLLGKPLIRVTGAENIRKILLGEHTVVCTQW--------PQSTRIILGPNTLVN 132

  Fly   124 LDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDV----RDLVARFTV 184
            ..|...:..|..|:..|:.|.::.....:..|.:..:|   :..:|...::|    :.|..|..|
Zfish   133 SVGDLHKRKRKVLAKVFSRGALEAYLTRLQDVVKSEIA---KWCTETGSVEVYTAAKSLTFRIAV 194

  Fly   185 DVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNL--------VSGLMRSYPNLARRLGLCR 241
            .|:    .|:   .|.:::..:|......|::    ||        ||||         |.|: |
Zfish   195 RVL----LGL---HLEEQQITYLSKTFEQLMN----NLFSLPIDTPVSGL---------RKGI-R 238

  Fly   242 NTAQIQEFYQRIVKETVTLREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFV 306
            ....:....::|::|  .|::::.....|..|.::....:.:..         |||.|:...|..
Zfish   239 AREILHSAMEKIIEE--KLKKQQASDYCDAFDYMLSSARENDYE---------LTMQELKETAVE 292

  Fly   307 FFIAGFDTSSSTMGFALYELAKNPSIQDKVRAEL---GQVLEQHD-------------------- 348
            ...|...|::|.....:.:|.::|.:.::.||||   |.:.:.|.
Zfish   293 LIFAAHSTTASASTSLIMQLLRHPDVSERARAELESEGLITDGHGHCRSRCNGNAISEEGEAAEK 357

  Fly   349 ---------QKFTY---------------------ECIKDLKYLDQVINETLRHYTIVPNVDRVA 383
                     .|.||                     |.:..|.|||.|:.|.||....|....|..
Zfish   358 STSDRRSAINKATYFEAGDKEEGRRSRTHVPYLSLEKLSQLSYLDCVVKEVLRFLPPVSGGYRTV 422

  Fly   384 AKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFS-PEESAKRPSVAWLPFGEG 447
            .:.|.:.|   :.|..|.||:......|.....|..|..|.|:||. ..|.:|....:::|||.|
Zfish   423 LQTFELNG---YQIPKGWSVMYSIRDTHETAEAYQNPELFDPDRFCVGREESKSERFSYVPFGGG 484

  Fly   448 PRNCIG 453
            .|.|||
Zfish   485 VRRCIG 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	95/457 (21%)
cyp26c1	NP_001025122.2	cytochrome_P450	59..537	CDD:477761	99/478 (21%)