Protein Alignment Cyp6a18 and cyp3a65

DIOPT Version :9

• Sequence 1: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001032515.1
• Gene: cyp3a65 / 553969
• ZFINID: ZDB-GENE-050604-1
• Length: 517
• Species: Danio rerio
• Alignment Length: 530
• Identity: 153/530 - (28%)
• Similarity: 255/530 - (48%)
• Gaps: 64/530 - (12%)

  Fly     4 TYFLFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIHQEYYNKYRN 68
            |:.|.....|||.|.....||   |||:.|||..|..|..|.|..||.  ..|....:.:.||
Zfish     7 TWTLLAFLAALLVIYGSWPHR---YFKKLGIPGPKAIPFFGTMLRYKD--GFHVFDMDCFEKY-- 64

  Fly    69 SKAPFVGFYLFQKPAAFVIDLELAKQILIK-------NFSNFTDKGIYYN-----EKDDPMSAHL 121
              ....|.|..::|...::|..:.|.:|||       |..||...|..|:     |.||
Zfish    65 --GRIWGIYDGRQPVLCIMDQTIIKTVLIKECYSLFTNRRNFRLNGALYDAVSIAEDDD------ 121

  Fly   122 FNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDV 186
                   ||.:||.||.:||||::|.|:..:...:...:..|.:........|:::....:::||
Zfish   122 -------WRRIRSVLSPSFTSGRLKEMFGIMKKHSHILVDSMGKTAKRGESADIKEFFGAYSMDV 179

  Fly   187 IGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLA---RRLGLCRNTAQIQE 248
            :.:.||.:..:||.:.|..|: ...:.:|.....|.:..|:..:|.:|   .::........:.:
Zfish   180 VTSTAFSVDIDSLNNPKDPFV-TNIKKMLKFDLLNPLFLLIAFFPFMAPVLEKMDFALFPTSVTD 243

  Fly   249 FY----QRIV--KETVTLREKENIKRNDFMDMLI----GLKNQKNMTLENGE-VVKGLTMDEIVA 302
            |:    |:|.  ::|.|:.:....||.||:.:::    |:|::     .:|| ..|||:..||::
Zfish   244 FFYAALQKIKSDRDTKTVAKDNTKKRVDFLQLMVDSQTGVKHK-----SDGEHTEKGLSDHEILS 303

  Fly   303 QAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVIN 367
            |:.:|..||::|||||:.|..|.||.||....|::.|:.:.. .:.....||.:..:.|||..::
Zfish   304 QSMIFIFAGYETSSSTLSFLFYNLATNPETMKKLQEEIDETF-PNQAPVDYETLMSMDYLDAALS 367

  Fly   368 ETLRHYTIVPNVDRVAAKRFVVPG--NPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSP 430
            |:||.:.:...::||..|...:.|  .||.::     |::|:.|:|.||..:.||..|:||||:.
Zfish   368 ESLRLFPVAARLERVCKKTVEINGLLIPKDLV-----VMVPTYALHRDPDYWSEPESFKPERFTK 427

  Fly   431 EESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHSAILLG 495
            ..........::|||.|||||||:||.|:..::.:..:::.|..|.|..|..||....:.  ||.
Zfish   428 GNKESIDPYMYMPFGLGPRNCIGMRFAQVTMKLAIVEILQRFDVSVCDETQVPLELGFNG--LLS 490

  Fly   496 IKGGIQLKVE 505
            .|..|:||::
Zfish   491 PKDPIKLKLQ 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	138/493 (28%)
cyp3a65	NP_001032515.1	p450	35..499	CDD:278495	139/496 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	226	1.000	Domainoid score	I2453
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8426
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.820