Protein Alignment Cyp6a18 and Cyp3a41a

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_059092.2
• Gene: Cyp3a41a / 53973
• MGIID: 1858451
• Length: 504
• Species: Mus musculus
• Alignment Length: 504
• Identity: 164/504 - (32%)
• Similarity: 260/504 - (51%)
• Gaps: 44/504 - (8%)

  Fly    14 LLAIVTYILHRKLT----YFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIHQEYYNKYRNSKAPFV 74
            ||||:..:|:|..|    .||::|||..||.|..|.:..|.|  .:.:...|.|.||..:...|.
Mouse    14 LLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYK--GLWKFDMECYEKYGKTWGLFD 76

  Fly    75 GFYLFQKPAAFVIDLELAKQILIKN-FSNFTDK------GIYYNEKDDPMSAHLFNLDGPQWRLL 132
            |    |.|...:.|.|:.|.:|:|. ||.||::      ||        ||..:......:|:..
Mouse    77 G----QMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGI--------MSKAISISKDEEWKRY 129

  Fly   133 RSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDVIGTCAFGIKCN 197
            |:.||.||||||:|.|:|.:....:..:..:.::..:...:.::|::..:::|||.:.:||:..:
Mouse   130 RALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYSIDVITSTSFGVNVD 194

  Fly   198 SLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLA---RRLGLCRNTAQIQEFYQRIVKETVT 259
            ||.:.:..|:...:..|.......||..:: .:|.|.   ..|.:|.......||:::.|.....
Mouse   195 SLNNPEDPFVEKAKGILRVDFFDPLVFSVV-LFPFLTPVYEMLNICMFPKDSIEFFKKFVNRMKE 258

  Fly   260 LR-EKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFAL 323
            .| :.:...|.||:.:::...|..    ::.:..|.|:..||.||:.||..||::|:|||:.|.|
Mouse   259 SRLDSKQKHRVDFLQLMMNAHNNS----KDKDSHKALSDMEITAQSIVFIFAGYETTSSTLSFTL 319

  Fly   324 YELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFV 388
            |.||.:|.||.|::.|:.:.|...... ||:.:.:::|||.|:|||||.|.|...::|...|...
Mouse   320 YCLATHPDIQKKLQEEIDETLPNKAPP-TYDTVMEMEYLDMVLNETLRLYPIGNRLERFCKKDVE 383

  Fly   389 VPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIG 453
            :.|   ..|..|.:|:|||.|:||||..:|||.||:|||||.|.........::|||.|||||||
Mouse   384 LNG---VYIPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGSIDPYLYMPFGIGPRNCIG 445

  Fly   454 LRFGQMQARIGLAMLIKNFTFSPCSATPDPL------TFDPHSAILLGI 496
            :||..|..::.|..:::||:|.||..|..||      ...|...|:|.:
Mouse   446 MRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSRQGLLQPEKPIVLKV 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	142/444 (32%)
Cyp3a41a	NP_059092.2	CYP3A	67..493	CDD:410743	143/446 (32%)