Protein Alignment Cyp6a18 and Cyp4f40

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001102830.1
• Gene: Cyp4f40 / 503122
• RGDID: 1559596
• Length: 523
• Species: Rattus norvegicus
• Alignment Length: 459
• Identity: 119/459 - (25%)
• Similarity: 210/459 - (45%)
• Gaps: 52/459 - (11%)

  Fly    75 GFYLFQKPAAFVIDL---ELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFNLDGPQWRLLRSKL 136
            ||..:..|...:|.|   ::.:.:|..:.:.....||:|:.....:...|......:|...||.|
  Rat    87 GFMTWLGPIVPLITLCHPDIIRSVLSASAAVAPKDGIFYSFLKPWLGDGLLVSASDKWSRHRSML 151

  Fly   137 SSTFTSGKMKFMYPTVVSVAEEFMAVMHEK----VSENSI-LDVRDLVARFTVDVIGTCAFGIKC 196
            :..|....:|    ..|.:..:...:||.|    .|..|. ||:.:.::..|:|.:..|.|....
  Rat   152 TPAFHFNILK----PYVKIFNDSTNIMHAKWLRLASGGSAHLDMFENISLMTLDTLQKCVFSFNS 212

  Fly   197 NSLRDEKAEFLH--FGRRALLDSRHGNL---VSGLMRSYPNLARRLGLCRNTAQIQEFYQRIVKE 256
            | .:::.:|::.  ....||:..|:..|   :..|.|..|:..|....|.   .:.:|...:::|
  Rat   213 N-CQEKPSEYIAAILELSALVVKRNEQLLLHMDLLYRLTPDGRRFYKACH---LVHDFTYAVIQE 273

  Fly   257 ---TV-------TLREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAG 311
               |:       .::.|...|..||:|:|:..|:      |:|   |.|:.::|.|:|..|...|
  Rat   274 RRRTLPKHGGDDVIKAKAKSKTLDFIDVLLLSKD------EDG---KELSDEDIRAEADTFMFEG 329

  Fly   312 FDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHD-QKFTYECIKDLKYLDQVINETLRHYTI 375
            .||::|.:.:.||.|||:|..|::.|.|:.::|...| ::..::.:..|.:|...|.|:||.:..
  Rat   330 HDTTASGLSWILYNLAKHPEYQERCRQEVQELLRDRDSEEIEWDDLAQLPFLTMCIKESLRLHPP 394

  Fly   376 VPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVA 440
            |..|.|...:...:|...  ||..|...||...|.||:|:::.:|..:.|.||.||....|..:|
  Rat   395 VTMVSRCCTQDISLPDGR--VIPKGIICIINIFATHHNPTVWQDPEVYDPFRFDPENIQARSPLA 457

  Fly   441 WLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATP--DPLTFDPHSAILLGIKGGIQLK 503
            ::||..|||||||..|...:.::.:|:.:..|...|....|  .|       .::|..:.|:.|:
  Rat   458 FIPFSAGPRNCIGQTFAMNEMKVAVALTLLRFRVLPDDKEPRRKP-------ELILRAEDGLWLR 515

  Fly   504 VEAI 507
            ||.:
  Rat   516 VEPL 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	115/450 (26%)
Cyp4f40	NP_001102830.1	CYP4F	74..515	CDD:410772	116/453 (26%)