Protein Alignment Cyp6a18 and LOC4577450

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_001230595.3
• Gene: LOC4577450 / 4577450
• VectorBaseID: AGAMI1_004862
• Length: 505
• Species: Anopheles gambiae
• Alignment Length: 544
• Identity: 128/544 - (23%)
• Similarity: 231/544 - (42%)
• Gaps: 101/544 - (18%)

  Fly     6 FLFQVAVALLAIVTY--ILHRKLT-YFKRRGIPYDKPHPLRGNMEGY--KKTRT---VHEIHQEY 62
            |.....:.||.:|.|  .|.||.: ....:.||..:.:||.|:...:  ...||   ::|:.::|
Mosquito     2 FFIPALILLLGLVLYWSKLSRKTSAQLFGKDIPGPRSYPLIGSAHLFLGSDERTFSVINELFRKY 66

  Fly    63 YNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYN--EKDDPMSAHLFNLD 125
            .:.::.|..|        |....:.|.:|.:|.|..  |...||..:|.  |.|..:.:..:.
Mosquito    67 GSFFKLSLGP--------KTFLCLSDPDLIQQALTS--SACQDKAFFYRFMELDYGLVSSRYT-- 119

  Fly   126 GPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFM-AVMHEKVSENSILDVRDLVARFTVDVIGT 189
              .|:|.|..|:..|.. ::...:.::.:...|.| |.|.::.......|.....|:.|.:::
Mosquito   120 --DWKLYRKSLNPAFNQ-RILISFISIFNRCSEVMVARMAKEADRRQPFDALHYTAQCTFEMV-- 179

  Fly   190 CAFGIKCNSLRDEKAEFLHFGRR---------ALLDSR------HGNLVSGLMRSYPNLARRLGL 239
            ||..:|.:...|.:|      |.         |::.||      :.:|:..|.:.|
Mosquito   180 CASSLKSDITHDPQA------REACGAIEKMCAIMSSRLFNVLLYSDLLFTLTQRY--------- 229

  Fly   240 CRNTAQIQEFYQRIV-------KETVTLREKENIKRND---------FMDMLIGLKNQKNMTLEN 288
             |...:::....|:|       :|.::.:..||....|         |:|.|:       .|...
Mosquito   230 -REMQKVRATLGRVVNPILYGRREKLSKQRLENAHSEDEEHYRKPMVFLDQLL-------HTQRG 286

  Fly   289 GEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTY 353
            |   :.|.:.||.........||.:|:::.:.|.|..||.:|.:|::|..|:..:........:|
Mosquito   287 G---RDLEIQEIENHLNTIIGAGSETTANQVAFILLMLAMHPEVQERVYEEIVSIYGSAASDLSY 348

  Fly   354 ECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYP 418
            |.|....||:|||.||:|.|.:.|.:.|...:. |..|:  .::..|.:::|....:|.:..::.
Mosquito   349 ETISAQTYLEQVIKETMRVYPVAPLIGRETIET-VKLGD--VIVPPGVTLLINILTVHRNKELWG 410

  Fly   419 E-PNEFRPERFSPE--ESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSAT 480
            | .:.|.|:||.|.  ::.|:...:::|||.|||||||.|:|....:|.:..:::.:..|
Mosquito   411 ERAHVFDPDRFDPAQYDAKKQHPFSYIPFGGGPRNCIGYRYGMFAMKIMVTQVLRKYQLS----- 470

  Fly   481 PDPLTFDPHSAILLGIKGGIQLKV 504
             .|||  |..::.|..  .:.|||
Mosquito   471 -TPLT--PTDSLRLSF--AVTLKV 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	107/466 (23%)
LOC4577450	XP_001230595.3	None