Protein Alignment Cyp6a18 and LOC4577431

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_001237417.1
• Gene: LOC4577431 / 4577431
• VectorBaseID: AGAMI1_011574
• Length: 462
• Species: Anopheles gambiae
• Alignment Length: 515
• Identity: 124/515 - (24%)
• Similarity: 200/515 - (38%)
• Gaps: 103/515 - (20%)

  Fly     8 FQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKT-----------RTVHEIH-- 59
            |.:|:....::|......|...|||.:..|:..|..|      :|           ||.|.|:
Mosquito     6 FWIALGTTVLLTGAFGLCLILDKRRSLWVDRRFPSTG------RTCVLYGDYGAAGRTEHRIYTT 64

  Fly    60 QEYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFNL 124
            |..|.::::.|.|..|..::..|.....|..|.:.:|.:.|..        |:|.....:.:|.
Mosquito    65 QRLYREFKSKKWPIGGALMYLTPCVIPTDPHLIEFLLNEEFGK--------NKKSSIAGSSIFR- 120

  Fly   125 DGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVA-EEFMAVMHEKVSENSILDVRDLVARFTVDVIG 188
              .:|        |:|....    |.::|:|| ||...|:....:....:||:.:...:.|.:|.
Mosquito   121 --KRW--------SSFEDEH----YNSLVNVATEESEKVVEMLCTSKQPVDVKVIAELYAVRMIA 171

  Fly   189 TCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLM-RSYPNLARRLGLCRNTAQIQEFYQR 252
            .|.||.:|..      |...|.....|.|:.|.:|..:. .::|:..       .||.:::....
Mosquito   172 RCVFGKRCTE------ESHTFPITEKLASQPGGIVWDVFSTAFPSTT-------FTATLRKLLDH 223

  Fly   253 IVKETVTLREKEN---IKRNDFMDMLIGLKNQKNMTLENGEVVKGLT---MDEIVAQAFVFFIAG 311
            ..|....|.|..:   .:|...::.|..||..:.....|..:..|.|   |.|:|..  |||:|
Mosquito   224 FQKHPALLDELVSSFLTERTADVNFLQHLKRTEQRAKANERIAFGDTRALMLELVQN--VFFVA- 285

  Fly   312 FDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIV 376
                |.|:...|:|:..|..||..:...|     |....|..:.      |:.||:||||.|..|
Mosquito   286 ----SGTIIACLFEMGHNGDIQKGLHETL-----QRSNPFAVDT------LENVISETLRKYPPV 335

  Fly   377 PNV-------DRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPER--FSPEE 432
            ..:       :|:.:...|||.|.:        |::|..|:.||...||:|..|.|:|  ||..|
Mosquito   336 GEISFVTVANNRLPSGELVVPKNTR--------VVVPIYALQHDAEHYPDPERFNPKRSIFSSSE 392

  Fly   433 SAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHSAI 492
            .    ||.:.|.|..|.. ||.....:..|:.|:.::...|......:|..|...|:.|:
Mosquito   393 Q----SVLYRPLGVQPLP-IGSSLALLMVRVALSNILGRCTVRLTPESPATLKISPNQAM 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	107/440 (24%)
LOC4577431	XP_001237417.1	cytochrome_P450	74..454	CDD:477761	107/441 (24%)