Protein Alignment Cyp6a18 and Cyp6a17

DIOPT Version :9

• Sequence 1: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001286433.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 504
• Identity: 250/504 - (49%)
• Similarity: 351/504 - (69%)
• Gaps: 10/504 - (1%)

  Fly     7 LFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIHQEYYNKYRNSKA 71
            |..:.|.:|:::.:...|:..|::|||||:|:.|||.||::.:...|.:.||.::||.||:||..
  Fly     3 LLALIVVILSLLVFAARRRHGYWQRRGIPHDEVHPLFGNIKDWPNKRHIAEIFRDYYFKYKNSDY 67

  Fly    72 PFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFNLDGPQWRLLRSKL 136
            ||.||:.|....|.|.|:||.|::|||:|::|.::|::|||.|||:||.||:::|.:||.||.||
  Fly    68 PFAGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRGVFYNEIDDPLSATLFSIEGQKWRHLRHKL 132

  Fly   137 SSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVS--ENSILDVRDLVARFTVDVIGTCAFGIKCNSL 199
            :.||||||||.|:|.||.|.||...|...|.:  ...:|:|.|||||:|.||||.||||:.||||
  Fly   133 TPTFTSGKMKNMFPIVVKVGEEMDKVFRSKTAADRGQVLEVVDLVARYTADVIGNCAFGLNCNSL 197

  Fly   200 RDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGLCRNTAQIQEFYQRIVKETVTLREKE 264
            .|.||||:..|:||:.:.|:||::...:..:|.|:|||.|..|..:.::||.:||:||:..|.:.
  Fly   198 YDPKAEFVSIGKRAITEHRYGNMLDIFLFGFPKLSRRLRLKLNIQEAEDFYTKIVRETIDYRLRT 262

  Fly   265 NIKRNDFMDMLIGL-KNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAK 328
            ..|||||||.||.: ||:     ::|....|||.:|::||||:||:|||:|||:||||||||||:
  Fly   263 KEKRNDFMDSLIEMYKNE-----QSGNSEDGLTFNELLAQAFIFFVAGFETSSTTMGFALYELAR 322

  Fly   329 NPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNP 393
            |..:|||:|.|:|.|..:|:::||||.||::|||:||:.||||.|.::.::.|:....| .|.:|
  Fly   323 NQDVQDKLREEIGNVFGKHNKEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDF-SPEDP 386

  Fly   394 KFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQ 458
            |:.|..|..|:||:..||:||.|||||..|:||||:.||.|.|||..|||||||||||||||||.
  Fly   387 KYFIAKGTIVVIPALGIHYDPDIYPEPEIFKPERFTDEEIAARPSCTWLPFGEGPRNCIGLRFGM 451

  Fly   459 MQARIGLAMLIKNFTFSPCSATPDPLTFDPHSAILLGIKGGIQLKVEAI 507
            ||..:|||.||:.:.||....|..|:.....: ||:..:.||.||||.:
  Fly   452 MQTCVGLAYLIRGYKFSVSPETQIPMKIVVKN-ILISAENGIHLKVEKL 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	236/468 (50%)
Cyp6a17	NP_001286433.1	p450	36..478	CDD:278495	231/447 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471827
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	1	1.000	-	-		H130979
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	12	11.800