Protein Alignment Cyp6a18 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_956773.1
• Gene: cyp46a1.4 / 393451
• ZFINID: ZDB-GENE-040426-1224
• Length: 444
• Species: Danio rerio
• Alignment Length: 486
• Identity: 119/486 - (24%)
• Similarity: 201/486 - (41%)
• Gaps: 83/486 - (17%)

  Fly    49 YKKTRTVHEIHQEYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEK 113
            |.....:|::..::..||    .|..........|..|...|..|.||:.  ..:|        |
Zfish     2 YADDSLIHDLFLQWAEKY----GPVYRINSLHYIAIVVHCPEATKTILMS--PKYT--------K 52

  Fly   114 DDPMSAHLFNLDGPQ--------------WRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMH 164
            |..:...||||.|.:              |...|..:...|:|..::.:..|...::|..|..:.
Zfish    53 DPFVYRRLFNLFGKRFLGYGLITAVDHDIWYRQRRIMDPAFSSSYLRSLISTFDEMSERLMDKLE 117

  Fly   165 EKVSENSILDVRDLVARFTVDVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRS 229
            |..:..:...:.|||...|:|||...|||:..|.|..:.:.|.: .....|:....:|.....|.
Zfish   118 EMANNKTPAVMHDLVNCVTLDVICKVAFGVDLNFLTQKDSPFQN-AVELCLNGMTVDLRDPFFRL 181

  Fly   230 YPNLARRLGLCRNTAQI-------------------QEFYQRIVKETVTLREKENIKRNDFMDML 275
            :|...:.:...|:.|::                   ::..:.|:.:.:...|:||:...|.::.:
Zfish   182 FPKNWKLIKQIRDAAELLRKTGEKWIQNRKTAVKNGEDVPKDILTQILKSAEEENVNNTDDLEQM 246

  Fly   276 IGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAEL 340
                                 :|..|    .|||||.:|:::.:.||:..|.:||.|..:.:||:
Zfish   247 ---------------------LDNFV----TFFIAGQETTANQLSFAIMALGRNPEIYKRAKAEV 286

  Fly   341 GQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVII 405
            .:||.. .::.:.|.:....||.||:.||||.|...|..:|...:..::.|   ..|..|.||:.
Zfish   287 DEVLGT-KREISNEDLGKFTYLSQVLKETLRLYPTAPGTNRWLHEDMIIDG---IKIPGGCSVMF 347

  Fly   406 PSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIK 470
            .|.........:.:|.:|.||||  :.:|.:|...:.||..|||.|:|..|.||:|::.||.|::
Zfish   348 SSYVSQRLEKFFKDPLKFDPERF--DVNAPKPYYCYFPFALGPRTCLGQVFSQMEAKVVLAKLLQ 410

  Fly   471 NFTFS--PCSA--TPDPLTFDPHSAILLGIK 497
            .|.||  |..:  ..|..|..|.|.::..||
Zfish   411 RFEFSLVPGQSFDIKDTGTLRPKSGVICNIK 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	115/465 (25%)
cyp46a1.4	NP_956773.1	CYP46A1-like	9..438	CDD:410706	116/474 (24%)